Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Tissue engineering (3)
- Concrete (2)
- Elastin (2)
- Hydrogel (2)
- Iron oxide (2)
-
- Life cycle assessment (2)
- Magnetic nanoparticle (2)
- Mapping (2)
- Model based control (2)
- Modeling (2)
- Morphology (2)
- Nanocomposites (2)
- NitroDOPA (2)
- Optimization (2)
- Resilience (2)
- Supercritical Extraction (2)
- 3D model (1)
- Abdominal aortic aneurysms (1)
- Abrasion loss (1)
- Adaptive Transmission (1)
- Adsorption (1)
- Aerosol (1)
- Aggregate (1)
- Aggregate properties (1)
- Air Content (1)
- Alkali (1)
- Alternative Fuel Vehicles (1)
- Ammonia (1)
- Amphiphilic block copolymers (1)
- Animal models (1)
Articles 1 - 30 of 86
Full-Text Articles in Entire DC Network
Vascular Nanomedicine: Site Specific Delivery Of Elastin Stabilizing Therapeutics To Damaged Arteries, Aditi Sinha
Vascular Nanomedicine: Site Specific Delivery Of Elastin Stabilizing Therapeutics To Damaged Arteries, Aditi Sinha
All Dissertations
Elastin, a structural protein in the extra-cellular matrix, plays a critical role in the normal functioning of blood vessels. Apart from performing its primary function of providing resilience to arteries, it also plays major role in regulating cell-cell and cell-matrix interactions, response to injury, and morphogenesis. Medial arterial calcification (MAC) and abdominal aortic aneurysm (AAA) are two diseases where the structural and functional integrity of elastin is severely compromised. Although the clinical presentation of MAC and AAA differ, they have one common underlying causative mechanism--pathological degradation of elastin. Hence prevention of elastin degradation in the early stages of MAC and …
Uv-Assisted Stabilization Of Polyacrylonitrile-Based Carbon Fiber Precursors, Marlon Salvador Morales Sandoval
Uv-Assisted Stabilization Of Polyacrylonitrile-Based Carbon Fiber Precursors, Marlon Salvador Morales Sandoval
All Dissertations
Due to their high strength and stiffness coupled with low density, carbon fibers are the preferred reinforcing fibers used in high-performance polymer matrix composites. Consequently, the demand for carbon fibers is expected to grow from 40,000 metric tons to about 150,000 metric tons over the next decade. A large fraction of the increase is anticipated in the industrial sector that is cost-sensitive. Therefore, there is a need for the development of novel processes and precursors to reduce the carbon fiber production cost and expand the use of carbon fibers. This research focuses on the development of an alternative, rapid stabilization …
Synthesis And Characterization Of Multi-Component Enrichment Polymer Layers For Chemical Sensor Applications, James Giammarco
Synthesis And Characterization Of Multi-Component Enrichment Polymer Layers For Chemical Sensor Applications, James Giammarco
All Dissertations
This dissertation presents the building and study of a "universal" enrichment polymer layer system (EPLS). Thin polymer films have been utilized as enrichment layers for evanescent waveguide chemical sensors. The chemical nature of the polymer provides affinity which promotes the analyte to be absorbed. Having one highly sensitive polymer layer is suitable for a single target volatile organic compound (VOC). Here, the development of multi-layered and multi-component thin polymer films has been done to allow for more diverse affinity. Several parameters were identified to make the EPLSs suitable as enrichment layers for chemical sensor devices. The evanescent sensor devices used …
Synthesis And Characterization Of Polymer Layers For Control Of Fluid Transport, Fehime Vatansever
Synthesis And Characterization Of Polymer Layers For Control Of Fluid Transport, Fehime Vatansever
All Dissertations
The level of wetting of fiber surface with liquids is an important characteristic of fibrous materials. It is related to fiber surface energy and the structure of the material. Surface energy can be changed by surface modification via the grafting methodologies that have been reported for introducing new and stable functionality to fibrous substrates without changing bulk properties.
Present work is dedicated to synthesis and characterization of macromolecular layers grafted to fiber surface in order to achieve directional liquid transport for the modified fabric. Modification technique used here is based on formation of stable polymer layer on fabric surface using …
Offshore Wind Energy Study And Its Impact On South Carolina Transmission System, Tingting Wang
Offshore Wind Energy Study And Its Impact On South Carolina Transmission System, Tingting Wang
All Dissertations
As one of the renewable resources, wind energy is developing dramatically in last ten years. Offshore wind energy, with more stable speed and less environmental impact than onshore wind, will be the direction of large scale wind industry. Large scale wind farm penetration affects power system operation, planning and control. Studies concerning type III turbine based wind farm integration problems such as wind intermittency, harmonics, low voltage ride through capability have made great progress. However, there are few investigations concerning switching transient impacts of large scale type III turbine based offshore wind farm in transmission systems. This topic will gain …
Study On Electromagnetic Scattering Of Cylinders Buried In A Half Space With Random Rough Surfaces Of Finite/Infinite Length, Yueyang Dai
All Dissertations
Analysis of electromagnetic scattering of buried objects is a subject of great interest due to its practical importance in both military and civil applications, such as subsurface investigation and target detection. In reality, the earth is of layered structure of random rough interfaces, which leads to a greatly increased complexity of the analysis. However, it is necessary to incorporate the nature of random rough surface and the layered structure because they both have substantial impact on the scattered signature and hence affect the study of inverse scattering and detection of buried objects. In this dissertation, a Monte-Carlo multidomain pseudospectral time …
Assessing Potential Environmental Impacts According To Probable Patterns Of Switchgrass Adoption In The Southeastern Us, Benjamin Sharp
Assessing Potential Environmental Impacts According To Probable Patterns Of Switchgrass Adoption In The Southeastern Us, Benjamin Sharp
All Dissertations
To assess the overall net impact of an emerging technology, life cycle assessment (LCA) must be accompanied by projections of adoption. Diffusion of innovation research provides tools that incorporate economic and social variables to explain and forecast integration of technologies. A switchgrass-to-ethanol case study for the southeastern U.S. is used to demonstrate methods for gauging aggregate environmental effects of an emerging energy technology. Before applying diffusion concepts, breakeven capacities are calculated for land in row crops, hay, pasture and marginal land. Breakeven curves are generated to provide upper bounds to switchgrass adoption over a range of farm-gate prices. The amount …
Biological Scaffolds For Peripheral Vascular Surgery, George Fercana
Biological Scaffolds For Peripheral Vascular Surgery, George Fercana
All Dissertations
The gold standards for small diameter peripheral vascular graft replacement are autologous arteries or veins; however, one-third of patients lack such vessels due to previous vessel harvesting or advanced vascular disease. A promising approach for patients in this category is tissue engineering with off-the-shelf biological vascular grafts. Three small diameter acellular scaffolds were developed and evaluated as vascular grafts. Porcine renal arteries (2-3 mm diameter, 20 mm length) were decellularized by immersion and stabilized with penta-galloyl glucose (PGG) with and without subsequent heparinization via carbodiimide chemistry. Bovine mammary (4-6 mm ID, 250 mm length) and femoral arteries (6-8 mm ID, …
Engineering Beta-Cell Spheroids For Type 1 Diabetes Treatment, Xiaoyan Liu
Engineering Beta-Cell Spheroids For Type 1 Diabetes Treatment, Xiaoyan Liu
All Dissertations
Diabetes mellitus, the third most common disease in the world, is a chronic metabolic disorder caused by a failure of insulin production and/or an inability to respond to insulin. Specifically, type 1 diabetes is a disorder characterized by targeted autoimmune-directed destruction of a patient's beta-cell population within the pancreatic islets of Langerhans. The current primary treatment for type 1 diabetes is daily multiple insulin injections. However, this treatment cannot provide sustained physiological release, and the insulin amount is not finely tuned to glycemia. Pancreatic transplants or islet transplants would be the preferred treatment method but the lack of donor tissue …
Identification Of Novel Genes Regulating Elastic Fiber Formation Through Expression Profiling Analysis Of Elastogenic Models, Erin Sproul
All Dissertations
Background: Particularly important to the mechanical performance of native arterial blood vessels is elastin, an extracellular matrix (ECM) protein deposited by VSMCs in the form of elastic fibers, arranged in concentric lamellae in the media of the vessel wall. In addition to serving as major structural elements of arterial walls, providing extensibility and elastic recoil, elastic fibers also influence vascular cell behaviors. For these reasons tissue engineers are attempting to exploit elastic fiber biology to enhance vascular graft design and patency. Therefore, developing a greater understanding of the molecular mechanisms of elastogenesis may offer opportunities to control elastogenesis in tissue …
Assessment Of The Human Factors Analysis And Classification System (Hfacs): Intra-Rater And Inter-Rater Reliability, Awatef Ergai
Assessment Of The Human Factors Analysis And Classification System (Hfacs): Intra-Rater And Inter-Rater Reliability, Awatef Ergai
All Dissertations
Human error has been identified as the primary contributing cause for up to 80% of the accidents in complex, high risk systems such as aviation, oil and gas, mining and healthcare. Many models have been proposed to analyze these incidents and identify their causes, focusing on the human factor. One such safety model is the Human Factors Analysis and Classification System (HFACS), a comprehensive accident investigation and analysis tool which focuses not only on the act of the individual preceding the accident but on other contributing factors in the system as well. Since its development, HFACS has received substantial research …
Effect Of Graphitic Carbon Nanomodifiers On The Electromagnetic Shielding Effectiveness Of Linear Low Density Polyethylene Nanocomposites, Byron Villacorta Hernandez
Effect Of Graphitic Carbon Nanomodifiers On The Electromagnetic Shielding Effectiveness Of Linear Low Density Polyethylene Nanocomposites, Byron Villacorta Hernandez
All Dissertations
Conductive polymer composites have become alternative materials for providing electromagnetic and electrostatic shielding where metals are not suitable. In this study, the effect of crystallinity, morphology, concentration and orientation of carbon nanomodifiers on shielding provided by their polyethylene-based composites has been investigated relative to their transport properties.
First, the electrical properties and EM SE of composites consisting of heat-treated carbon nanofibers (Pyrograf® -III PR-19 CNF) in a linear low density polyethylene (LLDPE) matrix were assessed. Heat treatment (HT) of CNF at 2500°C significantly improved their graphitic crystallinity and intrinsic transport properties, thereby increasing the EM SE of the nanocomposites. …
In Vitro Simulation Of Pathological Bone Conditions To Predict Clinical Outcome Of Bone Tissue Engineered Materials, Duong Nguyen
In Vitro Simulation Of Pathological Bone Conditions To Predict Clinical Outcome Of Bone Tissue Engineered Materials, Duong Nguyen
All Dissertations
According to the Centers for Disease Control, the geriatric population of ≥65 years of age will increase to 51.5 million in 2020; 40% of white women and 13% of white men will be at risk for fragility fractures or fractures sustained under normal stress and loading conditions due to bone disease, leading to hospitalization and surgical treatment. Fracture management strategies can be divided into pharmaceutical therapy, surgical intervention, and tissue regeneration for fracture prevention, fracture stabilization, and fracture site regeneration, respectively. However, these strategies fail to accommodate the pathological nature of fragility fractures, leading to unwanted side effects, implant failures, …
Sulfonated Perfluorocyclobutyl (Pfcb) Aryl Ether Polymers: Synthesis, Reactivity, And Characterization For Polymer Electrolyte Applications, Jiyoung Park
All Dissertations
Perfluorocyclobutyl (PFCB) aryl ether copolymers are excellent candidates for proton exchange membrane (PEM) component in PEM fuel cells. Sulfonated PFCB copolymer membranes exhibit not only high chemical/thermal/mechanical stability but also high proton conductivity. In this regard, PFCB aryl ether copolymers were synthesized via thermal step-growth [2 + 2] cyclopolymerization from aryl bis-(trifluorovinyl ether) (TFVE) monomers and oligomers. Experimental and computational studies confirmed that copolymerization of relatively electron-rich and electron-poor TFVE monomers gave selective-segmented copolymers in an one-pot polymerization. After sulfonation, the PFCB copolymers comprising hydrophilic and hydrophobic segments gave membranes with high proton conductivity. Cross-linked membranes of the sulfonated PFCB …
Application Of Image Processing And Finite Element Analysis In Modeling Chloride Diffusion In Concrete, Arash Razmjoo
Application Of Image Processing And Finite Element Analysis In Modeling Chloride Diffusion In Concrete, Arash Razmjoo
All Dissertations
Utilizing numerical simulation models to predict the long-term mechanical and transport behavior of concrete structures is becoming increasingly popular. The majority of these models have been developed using laboratory test data that consider concrete as a homogeneous material with spherical aggregates. These models could not be a represented of real concrete because it has no primitive shaped aggregate besides that the porosity size and distribution varies from point to point. In this study a novel method for more accurate prediction of the chloride diffusion in concrete was developed. A general framework of the quantitative computed tomography (QCT) and finite element …
Encapsulated And Monolithic Resonant Structures For Laser Applications, Aaron Pung
Encapsulated And Monolithic Resonant Structures For Laser Applications, Aaron Pung
All Dissertations
Typically, the composition of a laser system includes a gain medium, a pump illumination source, and an external feedback cavity. This cavity consists of a highly reflective mirror and an outcoupler component. The geometry of the outcoupler can be engineered to tailor the reflected or transmitted beam's spatial and spectral distribution. Functionally, the transmitted beam profile is dependent on the laser application. Broadband reflection profiles can be obtained by utilizing a distributed Bragg reflector (DBR). A DBR device consists of multiple layers of alternating materials. Constructive interference of the reflected light off each interface between different materials produces the spectrally …
Predicting Surgical Flow Disruption Recovery In Cardiothoracic Operating Rooms, Gary Palmer Ii
Predicting Surgical Flow Disruption Recovery In Cardiothoracic Operating Rooms, Gary Palmer Ii
All Dissertations
Disruptions are common occurrences in a variety of healthcare settings and early research has shown that they are likely contributors to medical errors. For this reason, healthcare researchers have focused on studying and understanding the nature of Surgical Flow Disruptions (SFDs) to increase patient safety and quality of care within the operating room (OR). Many researchers have used simplistic taxonomies to collect and categorize the types of SFD that occur within the OR. Others have gone further to study SFD recovery and have link unrecovered and recovered SFD to minor and major adverse events experienced by patients. This dissertation, focused …
Design And Synthesis Of Polymer - Magnetic Nanoparticle Composites For Use In Biomedical Applications, Roland Stone
Design And Synthesis Of Polymer - Magnetic Nanoparticle Composites For Use In Biomedical Applications, Roland Stone
All Dissertations
The future of diagnostics and therapeutic drugs in biomedicine is nanoparticles. These nanoparticles come in many different shapes, sizes, and combination of materials. Magnetic nanoparticles have been studied for many years for use in biomedicine, not only for their high surface area, but also because of its unique magnetic properties. They can magnetically interact with their environment, be guided to a specific location, and manipulated to release energy in the form of heat. To ensure that these magnetic nanoparticles survive in the circulatory system, they must be modified with materials to make them colloidally stable in water and shield them …
Primary Resonance Behavior Of Expanded Polymer Cushion Material Under Low-Intensity Harmonic Excitations, Gregory Batt
Primary Resonance Behavior Of Expanded Polymer Cushion Material Under Low-Intensity Harmonic Excitations, Gregory Batt
All Dissertations
The demand to lower costs and reduce the amount of packaging materials utilized in a packaged-product system has placed increased importance on the development of tools to model the behavior of packaging systems. In this dissertation, the free and forced vibration response of a nonlinear, distributed-parameter model of a viscoelastic rod with an applied tip-mass is used to investigate the response of expanded polymer cushion materials to low-intensity harmonic excitations. The rod and tip-mass represent an idealized packaged product system. A nonlinear model is developed from constitutive relations. A classical Maxwell-Weichert model, represented via a Prony series, is used to …
Seismic Site Coefficient Model And Improved Design Response Spectra Based On Conditions In South Carolina, Shimelies Aboye
Seismic Site Coefficient Model And Improved Design Response Spectra Based On Conditions In South Carolina, Shimelies Aboye
All Dissertations
A new seismic site coefficient model is developed from the results of over 60,000 total stress, one-dimensional equivalent ground response simulations assuming conditions in South Carolina. Computed site coefficients ( F ) are plotted versus average shear wave velocity in the top 30 m (VS30 ) and grouped by location, spectral acceleration (Soutcrop ) and spectral period. Locations considered in the Coastal Plain include Aiken, Charleston, Columbia, Florence, Lake Marion, Myrtle Beach, and the South Carolina side of Savannah. Locations considered in the Piedmont include Columbia, Greenville, Greenwood, and Rock Hill. In all the plots of …
Adaptive Transmission Protocols For Wireless Communication Systems With Fountain Coding, Jason Ellis
Adaptive Transmission Protocols For Wireless Communication Systems With Fountain Coding, Jason Ellis
All Dissertations
We present low-complexity adaptive protocols for both unicast and multicast transmission in wireless communication systems that employ higher layer fountain codes. Our adaptive protocols respond to variations in channel conditions by adapting the modulation and channel coding of transmitted packets, and they provide efficient communication over wireless channels that experience fading, shadowing, and other time-varying propagation losses. The operation of our protocols is governed by simple receiver statistics that can be obtained during the demodulation of received packets. We present three adaptive protocols for fountain-coded unicast transmission, and compare the throughput performance of our protocols with that of fixed-rate systems, …
Predictive Maturity Of Inexact And Uncertain Strongly Coupled Numerical Models, Ismail Farajpour
Predictive Maturity Of Inexact And Uncertain Strongly Coupled Numerical Models, Ismail Farajpour
All Dissertations
The Computer simulations are commonly used to predict the response of complex systems in many branches of engineering and science. These computer simulations involve the theoretical foundation, numerical modeling and supporting experimental data, all of which contain their associated errors. Furthermore, real-world problems are generally complex in nature, in which each phenomenon is described by the respective constituent models representing different physics and/or scales. The interactions between such constituents are typically complex in nature, such that the outputs of a particular constituent may be the inputs for one or more constituents. Thus, the natural question then arises concerning the validity …
Understanding The Role Of Requirements In Engineering Design By Novices, Shraddha Joshi
Understanding The Role Of Requirements In Engineering Design By Novices, Shraddha Joshi
All Dissertations
Requirements play a critical role in the design process. The broader impact of this research is to develop a systematic understanding of the current use of requirements with an ultimate goal to develop guidelines and recommendations for more effective use of requirements throughout the design process. Thus, this research begins to answer the question about what is the role of requirements in design process and, specifically, its role in idea generation? The answer to this question is explored in three phases. The first phase is to understand how requirements are currently taught to students. To that end, two surveys were …
Pyrene Oligomers: Their Isolation, Molecular Characterization, And Phase Behavior, David Esguerra Taborda
Pyrene Oligomers: Their Isolation, Molecular Characterization, And Phase Behavior, David Esguerra Taborda
All Dissertations
Carbonaceous pitches can serve as attractive precursors for advanced carbon materials such as high thermal conductivity fibers or carbon-carbon composites. Yet the effects of composition and molecular structure on the bulk properties (e.g., mesophase content and melting point) of these precursors remain only partly known, mainly because of the difficulties associated with the isolation, identification, and quantification of the large (i.e., molecular weight (mol wt) > 350-400 Da) polycyclic aromatic hydrocarbon (PAH) oligomers comprising these pitches. In this study, oligomeric fractions were isolated via supercritical extraction (SCE) from two representative pitches: a petroleum pitch (M-50) produced by the thermal polymerization of …
Optimization Of Porous Pavement Mixtures Based On Aggregate Structure, Andrew Neptune
Optimization Of Porous Pavement Mixtures Based On Aggregate Structure, Andrew Neptune
All Dissertations
Porous pavements are sustainable features that are used to help manage the quantity and quality of stormwater runoff. These pavements may include porous asphalt, permeable interlocking concrete pavers and pervious concrete. Since pavements that are purposefully designed to drain water through their matrix are relatively new, contractors and engineers are faced with various challenges such as improper design and installation, poor workability, and excessive finishing which may lead to clogged pores. Therefore, this study on porous pavements examined pervious concrete mixtures to evaluate an optimization process for the preparation of porous pavement mixtures based on aggregate structure to meet desired …
Characteristics And Contributing Factors Of Emergency Vehicle Crashes, Naji Abdelwanis
Characteristics And Contributing Factors Of Emergency Vehicle Crashes, Naji Abdelwanis
All Dissertations
The purpose of this study is to determine the contributing factors and characteristics associated with emergency vehicle(EV) crashes in order to generate insights about the emergency crashes. This dissertation consists of three approaches to address the purpose. In the first analysis a binary logistic regression model was used to identify the critical factors associated with EV crashes that resulted in fatality compared to those that did not. In the second analysis, an ordered regression model was used to identify critical factors that contributed to the severity of injuries that EV occupants experience in crashes as well as the effect of …
Enhancing Energy Efficiency In Connected Vehicles Via Access To Traffic Signal Information, Grant Mahler
Enhancing Energy Efficiency In Connected Vehicles Via Access To Traffic Signal Information, Grant Mahler
All Dissertations
This dissertation expounds on algorithms that can deterministically or proba-bilistically predict the future Signal Phase and Timing (SPAT) of a traffic signal by relying on real-time information from numerous vehicles and traffic infrastructure, historical data, and the computational power of a back-end computing cluster. When made available on an open server, predictive information about traffic signals’ states can be extremely valuable in enabling new fuel efficiency and safety functionalities in connected vehicles: Predictive Cruise Control (PCC) can use the predicted timing plan to calculate globally optimal velocity trajectories that reduce idling time at red signals and therefore improve fuel efficiency …
Exploring Multiple Levels Of Performance Modeling For Heterogeneous Systems, Venkittaraman Vivek Pallipuram Krishnamani
Exploring Multiple Levels Of Performance Modeling For Heterogeneous Systems, Venkittaraman Vivek Pallipuram Krishnamani
All Dissertations
The current trend in High-Performance Computing (HPC) is to extract concurrency from clusters that include heterogeneous resources such as General Purpose Graphical Processing Units (GPGPUs) and Field Programmable Gate Array (FPGAs). Although these heterogeneous systems can provide substantial performance for massively parallel applications, much of the available computing resources are often under-utilized due to inefficient application mapping, load balancing, and tuning. While several performance prediction models exist to efficiently tune applications, they often require significant computing architecture knowledge for reliable prediction. In addition, they do not address multiple levels of design space abstraction and it is often difficult to choose …
A Hybrid Method Of Performing Electric Power System Fault Ride-Through Evaluations On Medium Voltage Multi-Megawatt Devices, John Fox
All Dissertations
This dissertation explores the design and analysis of a Hybrid Method of performing electrical power system fault ride-through evaluations on multi-megawatt, medium voltage power conversion equipment. Fault ride-through evaluations on such equipment are needed in order to verify and validate full scale designs prior to being implemented in the field. Ultimately, these evaluations will help in reducing the deployment risks associated with bringing new technologies into the marketplace. This is especially true for renewable energy and utility scale energy storage systems, where a significant amount of attention in recent years has focused on their ever increasing role in power system …
Large Scale 3d Mapping Of Indoor Environments Using A Handheld Rgbd Camera, Brian Peasley
Large Scale 3d Mapping Of Indoor Environments Using A Handheld Rgbd Camera, Brian Peasley
All Dissertations
The goal of this research is to investigate the problem of reconstructing a 3D representation of an environment, of arbitrary size, using a handheld color and depth (RGBD) sensor. The focus of this dissertation is to examine four of the underlying subproblems to this system: camera tracking, loop closure, data storage, and integration. First, a system for 3D reconstruction of large indoor planar environments with data captured from an RGBD sensor mounted on a mobile robotic platform is presented. An algorithm for constructing nearly drift-free 3D occupancy grids of large indoor environments in an online manner is also presented. This …