Digital Commons Network^™

Effects Of Non-Equilibrium Plasma On Eukaryotic Cells (Final Report: Grant Fa9550-06-1-0004), Mounir Laroussi, Fred C. Dobbs, Old Dominion University

Electrical & Computer Engineering Faculty Publications

This document is our final report describing the research activities carried out under AFOSR Grant FA9550-06-1-0004. First, descriptions of our cold plasma generation systems are presented. Two systems, developed with past and present AFOSR support, are available in our laboratory. The first is a pulsed device capable of emitting a cold plasma plume in room air. The second is an air plasma generator the core of which is a dielectric barrier discharge excited by a high AC voltage. Following these brief descriptions we first present the effects of an atmospheric pressure air plasma on four different types of eukaryotic microalgae. …

Adding Escience Assets To The Data Web, Herbert H. Van De Sompel, Carl Lagoze, Michael L. Nelson, Simeon Warner, Robert Sanderson, Pete Johnston

Computer Science Faculty Publications

Aggregations of Web resources are increasingly important in scholarship as it adopts new methods that are data-centric, collaborative, and networked-based. The same notion of aggregations of resources is common to the mashed-up, socially networked information environment of Web 2.0. We present a mechanism to identify and describe aggregations of Web resources that has resulted from the Open Archives Initiative - Object Reuse and Exchange (OAI-ORE) project. The OAI-ORE specifications are based on the principles of the Architecture of the World Wide Web, the Semantic Web, and the Linked Data effort. Therefore, their incorporation into the cyberinfrastructure that supports eScholarship will …

Conceptual Requirements For Command And Control Languages, Andreas Tolk, Curtis L. Blais, Saikou Y. Diallo, Charles Turnitsa

Computational Modeling & Simulation Engineering Faculty Publications

The current Coalition Battle Management Language initiative (C-BML) will define a language to unambiguously exchange command and control information between systems. This paper introduces a categorization that may be used to guide the process of developing C-BML effectively by enumerating the conceptual requirements the authors have identified in model-based data engineering and process engineering based studies in various domains.

First, it is important to distinguish if application of the language will support the planning, execution, or observation phase of command and control. While C-BML already distinguishes between tasking and reporting, planning is a category with different requirements.

Second, the language …

Harmonizing Bml Approaches: Grammars And Data Models For A Bml Standard, Dietmar Kunde, Thomas Orichel, Andreas Tolk, Ulrich Schade, Michael R. Hieb

Computational Modeling & Simulation Engineering Faculty Publications

Battle Management Language (BML) is being developed as an open standard that unambiguously formalizes and specifies Command and Control information, including orders and reports built upon precise representations of tasks. BML is a language specification, based on doctrine and consistent with Coalition standards. The goal of BML is to enable and improve the interoperability in the C2 area, especially by enabling also the military communication with simulation systems and future robotic forces.

Although the need for BML is well documented, a SISO standard has still not been achieved. At present, there are two recommended approaches focusing on different aspects. In …

Utilizing Strategic Project Management Processes And The Nato Code Of Best Practice To Improve Management Of Experimentation Events, Andreas Tolk, Rafael E. Landaeta, Robert H. Kewley, Thomas T. Litwin

Computational Modeling & Simulation Engineering Faculty Publications

Systems engineering and project management are two core engineering management processes supported by core quantitative disciplines within engineering management problems. Traditional approaches to systems engineering focus on a single system being engineered and managed (i.e., project managed), while challenges addressing composition of systems of systems and the reuse of systems for new solutions require a strategic management approach that promote a process flow in which the outputs of one project (e.g., deliverables, knowledge, work documents) are captured for the benefit of other projects within and outside the project-based organization. Two other core processes of engineering management are therefore critical to …

Understanding Practical Limits To Heavy Truck Drag Reduction, Drew Landman, Richard Wood, Whitney Seay, John Bledsoe

Mechanical & Aerospace Engineering Faculty Publications

A heavy truck wind tunnel test program is currently underway at the Langley Full Scale Tunnel (LFST). Seven passive drag reducing device configurations have been evaluated on a heavy truck model with the objective of understanding the practical limits to drag reduction achievable on a modern tractor trailer through add-on devices. The configurations tested include side skirts of varying length, a full gap seal, and tapered rear panels. All configurations were evaluated over a nominal 15 degree yaw sweep to establish wind averaged drag coefficients over a broad speed range using SAE J1252. The tests were conducted by first quantifying …

International Service Learning Projects For Senior Capstone Projects, Steve Reichle, Avery Bang, Carol Considine

Engineering Technology Faculty Publications

Service learning is being adopted in many engineering programs at various course levels. International service learning experiences can provide senior level engineering students with opportunities to practice the required skills of engineering graduates as detailed by the ABET Criteria for Accrediting Engineering Programs. Bridges to Prosperity is a non-profit organization that builds footbridges in rural third world communities. These design build footbridge projects require a full year for fundraising, site visit, design and construction, and provide engineering students an opportunity to practice their knowledge of globalization, sustainability, engineering design, teamwork, and leadership. A team of students from the University of …

Dc Electrokinetic Transport Of Cylindrical Cells In Straight Microchannels, Ye Ai, Ali Beskok, David T. Gauthier, Sang W. Joo, Shizhi Qian

Biological Sciences Faculty Publications

Electrokinetic transport of cylindrical cells under dc electric fields in a straight microfluidic channel is experimentally and numerically investigated with emphasis on the dielectrophoretic (DEP) effect on their orientation variations. A two-dimensional multiphysics model, composed of the Navier-Stokes equations for the fluid flow and the Laplace equation for the electric potential defined in an arbitrary Lagrangian-Eulerian framework, is employed to capture the transient electrokinetic motion of cylindrical cells. The numerical predictions of the particle transport are in quantitative agreement with the obtained experimental results, suggesting that the DEP effect should be taken into account to study the electrokinetic transport of …

Cold Plasma Technology: Bactericidal Effects On Geobacillus Stearothermophilus And Bacillus Cereus Microorganisms, Angela D. Morris, Gayle B. Mccombs, Tamer Akan, Wayne L. Hynes, Mounir Laroussi, Susan L. Tolle

Dental Hygiene Faculty Publications

Introduction: Cold plasma, also known as Low Temperature Atmospheric Pressure Plasma (LTAPP) is a novel technology consisting of neutral and charged particles, including free radicals, which can be used to destroy or inactivate microorganisms. Research has been conducted regarding the effect of cold plasma on gram-positive bacteria; however, there is limited research regarding its ability to inactivate the spore-formers Geobacillus stearothermophilus and Bacillus cereus.

Purpose: The purpose of this study was to determine if cold plasma inactivates G. stearothermophilus and B. cereus vegetative cells and spores.

Methods: Nine hundred eighty-one samples were included in this study (762 experimental and …

Precise Measurement Of The Neutron Magnetic Form Factor Gnm In The Few-Gev² Region, Clas Collaboration, J. Lachniet, H. Bagdasaryan, S. Bültmann, N. Kalantarians, G. E. Dodge, T. A. Forest, G. Gavalian, C. E. Hyde-Wright, A. Klien, S. E. Kuhn, M. R. Niroula, R. A. Niyazov, L. M. Qin, L. B. Weinstein, J. Zhang

Physics Faculty Publications

The neutron elastic magnetic form factor was extracted from quasielastic electron scattering on deuterium over the range Q² = 1.0–4.8  GeV² with the CLAS detector at Jefferson Lab. High precision was achieved with a ratio technique and a simultaneous in situ calibration of the neutron detection efficiency. Neutrons were detected with electromagnetic calorimeters and time-of-flight scintillators at two beam energies. The dipole parametrization gives a good description of the data

Exploring Primitives Of Meaning In Support Of Interoperability, Charles D. Turnitsa, Andreas Tolk, Robert Kewley

Computational Modeling & Simulation Engineering Faculty Publications

Semantic mismatch between systems is due, in part, to the grouping together of terms who have defined meaning in different levels of granularity, and which are composed together into different groupings by distinct systems. It has been proposed that making use of elemental concepts (referred to here as primitives of meaning) can assist in interoperability, but seeking to define all terms at a level of granularity equal to or greater than that of all involved systems.

By decomposing a system’s groups of composed terms into primitives of meaning, the building blocks that can be reassembled into the compositions required by …

An Extended Interoperability Framework For Joint Composability, Andreas Tolk, Charles D. Turnitsa

Computational Modeling & Simulation Engineering Faculty Publications

Interoperation of systems is defined by the aspects of integratability, interoperability, and composability. It is therefore needed, to address all levels of interoperation - from conceptual models via implemented systems to the supported infrastructure - accordingly in an interoperation framework.

Several candidates are available and provide valuable part solution. This paper evaluates the Base Object Models (BOMs), Discrete Event Simulation Specifications (DEVS), Unified Language Model (UML) artifacts as used within the Test and Training Enabling Architecture (TENA), the Object-Process Methodology (OPM), and Conceptual Graphs (CG) regarding their contribution.

Using the Levels of Conceptual Interoperability Model (LCIM), an extended interoperability framework …

Applying Model-Based Data Engineering To Evaluate The Alignment Of Information Modeled Within Jc3iedm, Msdl, And Matrex-Fom, Anil Ustun, Andreas Tolk, Saikou Diallo

Computational Modeling & Simulation Engineering Faculty Publications

The need for a common representation of entities and their relations to support the easier composition and federation of independently developed solutions in support of the user has been identified and addressed in several papers presented during recent simulation interoperability workshop. One of the underlying assumptions is that standards derived from the same conceptual domain can easily be converted into each others, as they deal with the same concepts. In a project conducted for the U.S. Army’s Program Executive Office (PEO) Soldier, three of such solutions for military operations (with focus on the land forces) were utilized to capture the …

C2 Domain Ontology Within Our Lifetime, Leslie Winters, Andreas Tolk

Computational Modeling & Simulation Engineering Faculty Publications

Agile Command and Control (C2) requires agile information sharing with an increasingly wide variety of military and non-military partners. While current net-centric approaches may improve information sharing within a particular niche of C2, they do not support information sharing across the larger C2 domain. Although not a silver bullet, the development and application of a C2 domain ontology to improve C2 data and service integration appears to be increasingly realistic. In fact, there are several examples of successful ontology applications in domains such as medicine, biology, and engineering, and the new discipline of Applied Ontology is emerging. C2 data, architecture, …

Multicast Encryption Infrastructure For Security In Sensor Networks, Richard R. Brooks, Brijesh Pillai, Matthew Pirretti, Michele C. Weigle

Computer Science Faculty Publications

Designing secure sensor networks is difficult. We propose an approach that uses multicast communications and requires fewer encryptions than pairwise communications. The network is partitioned into multicast regions; each region is managed by a sensor node chosen to act as a keyserver. The keyservers solicit nodes in their neighborhood to join the local multicast tree. The keyserver generates a binary tree of keys to maintain communication within the multicast region using a shared key. Our approach supports a distributed key agreement protocol that identifies the compromised keys and supports membership changes with minimum system overhead. We evaluate the overhead of …

Analysis Of Possible Use Of Identification Technologies In Disassembly, Vukica Jovanović, Sreten Filipović, Gordana Ostojić, Stevan Stankovski, Milovan Lazarević

Engineering Technology Faculty Publications

The barcodes and Radio Frequency Identification tags that are being used during manufacturing, assembly, warehousing, and distribution could also be reused at the end of the product lifecycle for an identification of the correct disassembly process that would result in recycling of its components. The barcodes or RFID tags can be helpful in identifying objects in terms of sustainable development, regarding disassembly, recycling and reuse. In this paper, the analysis of the current applications of RFID Technology in the final phase of the product lifecycle will be presented. The simulation of the disassembly process supported by both barcode and RFID-enabled …

System Design And Integration For Repeated Impact Tests, Cheng Lin, Gene Hou, Sebastian Bawab, Timothy Coats, Hesham Nassar

Engineering Technology Faculty Publications

The design and integration of an impact-testing machine is particularly for the test of an object which is repeatedly dropped down from a specified height. Four linear actuators with two on each of the two magnetic rails are used to lift up an object weighing up to 70 lbs. Each actuator is powered and controlled by an industrial amplifier. A Programmable Logical Controller (PLC) is applied to activate these four actuators simultaneously and repeatedly. Accelerometers using an National Instruments (NI) data acquisition system are used to measure the impact force during the tests. Students gain design and implementation experiences from …

A Comparison Of Instructional Delivery Methods Based On Student Evaluation Data, John Hackworth, Carol Considine, Vernon Lewis

Engineering Technology Faculty Publications

Distance Education is an increasingly common educational delivery method. At Old Dominion University, all junior and senior level engineering technology courses are offered via distance education at least once every two years. A majority of courses in the distance education system at this university have three simultaneous delivery methods: on-campus, televised (receiving the course at an off-campus site via satellite video/audio), and internet-based video-streamed.

This paper explores the results of student course evaluation surveys for trends, in particular those trends which can be a result of the mode of delivery. Results of these surveys for 23 courses over a 4-year …

Pressure-Driven Transport Of Particles Through A Converging-Diverging Microchannel, Ye Ai, Sang W. Joo, Xiangchun Xuan, Shizhi Qian

Mechanical & Aerospace Engineering Faculty Publications

Pressure-driven transport of particles through a symmetric converging-diverging microchannel is studied by solving a coupled nonlinear system, which is composed of the Navier-Stokes and continuity equations using the arbitrary Lagrangian-Eulerian finite-element technique. The predicted particle translation is in good agreement with existing experimental observations. The effects of pressure gradient, particle size, channel geometry, and a particle's initial location on the particle transport are investigated. The pressure gradient has no effect on the ratio of the translational velocity of particles through a converging-diverging channel to that in the upstream straight channel. Particles are generally accelerated in the converging region and then …

Synthesis And Characterization Of Birnessite And Cryptomelane Nanostructures In Presence Of Hoffmeister Anions, Marcos A. Cheney, Robin Jose, Arghya Banerjee, Pradip K. Bhowmik, Shizhi Qian, Joseph M. Okoh

Mechanical & Aerospace Engineering Faculty Publications

The effect of Hoffmeister anions Cl(-), SO(4) (2-), and ClO(4) (-) on the structure and morphology of birnessite and cryptomelane-type manganese dioxide nanostructures, produced by the reduction reaction of KMnO(4) and MnSO(4) in aqueous acidic media, was studied. The syntheses were based on the decomposition of aqueous KMnO(4) in presence of HCl for birnessite-type and acidified MnSO4 for cryptomelane-type manganese dioxide under soft hydrothermal conditions. They were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and high-resolution transmission electron microscopy (HRTEM) techniques. XRD patterns show the formation of birnessite for the first synthesis and a mixture of cryptomelane and …

Volume Viscosity In Fluids With Multiple Dissipative Processes, Allan J. Zuckerwar, Robert L. Ash

Mechanical & Aerospace Engineering Faculty Publications

The variational principle of Hamilton is applied to derive the volume viscosity coefficients of a reacting fluid with multiple dissipative processes. The procedure, as in the case of a single dissipative process, yields two dissipative terms in the Navier-Stokes equation: The first is the traditional volume viscosity term, proportional to the dilatational component of the velocity; the second term is proportional to the material time derivative of the pressure gradient. Each dissipative process is assumed to be independent of the others. In a fluid comprising a single constituent with multiple relaxation processes, the relaxation times of the multiple processes are …

Regulation Of Intracellular Calcium Concentration By Nanosecond Pulsed Electric Fields, Shaka S. Scarlett, Jody A. White, Peter F. Blackmore, Karl H. Schoenbach, Juergen Kolb

Bioelectrics Publications

Changes in [Ca²⁺]_i response of individual Jurkat cells to nanosecond pulsed electric fields (nsPEFs) of 60 ns and field strengths of 25, 50, and 100 kV/cm were investigated. The magnitude of the nsPEF-induced rise in [Ca²⁺]_i was dependent on the electric field strength. With 25 and 50 kV/cm, the [Ca²⁺]_i response was due to the release of Ca²⁺ from intracellular stores and occurred in less than 18 ms. With 100 kV/cm, the increase in [Ca²⁺]_i was due to both internal release and to influx across the plasma …

Rapid Sensor Technology: A Risk And System Complexity Analyses Of Early Detection Of Influenza-Like-Illnesses, Cesar Ariel Pinto, Ipek Bozkurt

Engineering Management & Systems Engineering Faculty Publications

The development of effective and reliable methods to defend the nation against biological terrorism remains an urgent challenge to researchers in the areas of risk, bio-defense, public health, and emergency medicine. The emerging threat of the avian flu pandemic also highlights the unpreparedness of our nation's health care system to meet a highly contagious and infectious disease outbreak. The implementation of a rapid sensor technology for early detection of influenza-like-illness provides possible opportunities, as well as problems. Bounding and defining such a complex problem is one of the first challenges this research addresses. Approaching this problem from various perspectives such …

Embedding Simulation Education Into The Engineering Management Body Of Knowledge, Andreas Tolk, Ghaith Rabadi, Donald N. Merino

Computational Modeling & Simulation Engineering Faculty Publications

The American Society for Engineering Management (ASEM) established a Body of Knowledge (BoK). As simulation is of growing interest to engineers in general and to engineering managers in particular, simulation is part of this documentation of domains of interest that characterise the profession. The basis for the Body of Knowledge comprises of established and accredited curricula and additional input from practitioners of the field. As it is essential to cover the basic topics and core competences as well as application specific domain knowledge, the simulation education for engineers is categorised into topics on simulation theory and simulation application.

A Logistic Approximation To The Cumulative Normal Distribution, Shannon R. Bowling, Mohammad T. Khasawneh, Sittichai Kaewkuekool, Byung R. Cho

Engineering Management & Systems Engineering Faculty Publications

This paper develops a logistic approximation to the cumulative normal distribution. Although the literature contains a vast collection of approximate functions for the normal distribution, they are very complicated, not very accurate, or valid for only a limited range. This paper proposes an enhanced approximate function. When comparing the proposed function to other approximations studied in the literature, it can be observed that the proposed logistic approximation has a simpler functional form and that it gives higher accuracy, with the maximum error of less than 0.00014 for the entire range. This is, to the best of the authors’ knowledge, the …

Sensitivity Analysis Framework For Large And Complex Simulation Models, Ghaith Rabadi, Shannon Bowling, Charles Keating, Resit Unal

Engineering Management & Systems Engineering Faculty Publications

In this paper, a framework for conducting Sensitivity Analysis (SA) on large and complex simulation models is introduced. The framework consists of components that are designed to make the SA a systematic process that is easy to manage and follow by simulation analysts and practitioners. Unlike local SA (one-variable-at-a-time SA), the method presented here is variance-based and it is rooted in the field of Design of Experiments (DoE) where Input Variables are varied and Output Variables are measured. Based on the DoE results, a risk scoring system is developed to identify the sensitivity of the Input Variables, and as a …

Energy From The Skies: Empowering Future Generations, Petros J. Katsioloudis, Stella Bondi, Walter F. Deal

STEMPS Faculty Publications

The article discusses the development of photovoltaic technology. The first account of the use of solar power during war in western civilization was in the second century B.C. during the battle of Syracuse with Archimedes' famed Death Ray. In the late 1800s and early 1900s many advances occurred including the invention of solar-powered engines, the discovery of the photoconductivity of selenium and its ability to produce electricity when exposed to light, and the construction of the first solar cells from selenium wafers. Photovoltaic technology was born in the U.S. in 1954 when Daryl Chapin, Calvin Fuller, and Gerald Pearson developed …

Biomedical Technology: Supporting Movement, Petros Katsioloudis

STEMPS Faculty Publications

According to the National Institute on Disability and Rehabilitation Research, an estimated 8.5 million children 21 years and younger have a disability (Jans & Stoddard, 1999). After about a decade, with the development of new and sophisticated materials (aluminum alloys, titanium alloys, and carbon fibers) and the integration of electronics, it was then possible to significantly improve the performance of prostheses, built with the so-called endo skeletal (or skeletal-modular) method (Mora, Beratni & Pedrotti, 2006).

Parameter Optimization For Image Denoising Based On Block Matching And 3d Collaborative Filtering, Ramu Pedada, Emin Kugu, Jiang Li, Zhanfeng Yue, Yuzhong Shen, Josien P.W. Pluim (Ed.), Benoit M. Dawant (Ed.)

Electrical & Computer Engineering Faculty Publications

Clinical MRI images are generally corrupted by random noise during acquisition with blurred subtle structure features. Many denoising methods have been proposed to remove noise from corrupted images at the expense of distorted structure features. Therefore, there is always compromise between removing noise and preserving structure information for denoising methods. For a specific denoising method, it is crucial to tune it so that the best tradeoff can be obtained. In this paper, we define several cost functions to assess the quality of noise removal and that of structure information preserved in the denoised image. Strength Pareto Evolutionary Algorithm 2 (SPEA2) …

Automatic Diagnosis For Prostate Cancer Using Run-Length Matrix Method, Xiaoyan Sun, Shao-Hui Chuang, Jiang Li, Frederic Mckenzie, Nico Karssemeijer (Ed.), Maryellen L. Giger (Ed.)

Electrical & Computer Engineering Faculty Publications

Prostate cancer is the most common type of cancer and the second leading cause of cancer death among men in US¹. Quantitative assessment of prostate histology provides potential automatic classification of prostate lesions and prediction of response to therapy. Traditionally, prostate cancer diagnosis is made by the analysis of prostate-specific antigen (PSA) levels and histopathological images of biopsy samples under microscopes. In this application, we utilize a texture analysis method based on the run-length matrix for identifying tissue abnormalities in prostate histology. A tissue sample was collected from a radical prostatectomy, H&E fixed, and assessed by a pathologist …