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Chemistry

Western Michigan University

Dissertations

Theses/Dissertations

2012

Sensors; optical; fluorescein; nerve gas mimics; coumarin; electrochemical

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Optical And Electrochemical Sensors For The Detection Of Metal Ions And Nerve Gas Mimics Via Fluorescein And Coumarin Derivatives, Fasil Adefris Abebe Apr 2012

Optical And Electrochemical Sensors For The Detection Of Metal Ions And Nerve Gas Mimics Via Fluorescein And Coumarin Derivatives, Fasil Adefris Abebe

Dissertations

Trace element detection of metals, for example, iron, Copper and zinc, are important in biological systems and in the environment. Many of us are aware that our cells contain metal ions that are “tied” up in proteins. However, chelatable or “free” trace elements can also be found in small quantities, and can have a negative impact on our bodies. Despite the increasing surge in developing sensors for metals and nerve gas agents, efficient detection still remains a challenge. Among the various sensors developed so far, fluorescence sensors play an important role due to their simplicity. I design fluorescein-based chemosensors for …