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Chemistry

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University of Texas Rio Grande Valley

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2019

Druggability

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Phytochemical Investigation Of Magnolia Grandiflora Green Seed Cones: Analytical And Phytoceutical Studies, Bo Garza, Alondra Echeverria, Felipe Gonzalez, Orlando Castillo, Thomas Eubanks, Debasish Bandyopadhyay Apr 2019

Phytochemical Investigation Of Magnolia Grandiflora Green Seed Cones: Analytical And Phytoceutical Studies, Bo Garza, Alondra Echeverria, Felipe Gonzalez, Orlando Castillo, Thomas Eubanks, Debasish Bandyopadhyay

Chemistry Faculty Publications and Presentations

Phytochemicals are inevitable part of human civilization. It is impossible to say exactly when menfolk started to take plant portions to cure various diseases. Phytochemical investigation of diethyl ether and ethanol extracts of Magnolia grandiflora green seed cones has been carried out. Extraction, isolation, and identification of the phytochemicals were carried out. Structures were determined by various analytical methods including extensive nuclear magnetic resonance, gas chromatography‐ mass spectroscopy, and X‐ray crystallographic analyses. Structures of the three compounds viz. 5,5′‐diallyl‐[1,1′‐biphenyl]‐2,2′‐diol (I), 3′,5‐diallyl‐[1,1′‐biphenyl]‐2,4′‐ diol (II), and (3S,3aS,8S,9aS,10aR,10bS,E)‐8‐hydroxy‐3,6,9a‐trimethyl‐3a,4,5,8,9,9a, 10a,10b‐octahydrooxireno[2′,3′:9,10]cyclodeca[1,2‐b]furan‐2(3H)‐one (III) were confirmed by X‐ray crystallographic analysis. GS‐MS studies of the isolated oil, eluted …