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Using Ega-Gc To Analyze Nicotine N-Oxide In Order To Explain Low Nicotine Concentrations In E-Cigarette Liquids, Cory Wuerch
Using Ega-Gc To Analyze Nicotine N-Oxide In Order To Explain Low Nicotine Concentrations In E-Cigarette Liquids, Cory Wuerch
Undergraduate Honors Thesis Collection
Evolved-gas analysis coupled with gas chromatography (EGA-GC) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration. A possible explanation for this phenomenon is that the nicotine in the liquids is being oxidized to nicotine N-oxide by exposure to air and thus reducing the concentration of nicotine. This study focused on analyzing samples of thermally-rearranged nicotine N-oxide. Using EGA-GC, a calibration curve was generated for nicotine N-oxide concentration, which could potentially be used to explain reduced nicotine concentrations in e-cigarette liquids.