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Articles 1 - 7 of 7
Full-Text Articles in Entire DC Network
Plant Litter Quality Affects The Accumulation Rate, Composition, And Stability Of Mineral-Associated Soil Organic Matter, S. Carolina Córdova, Dan C. Olk, Ranae N. Dietzel, Kevin E. Mueller, Sotirios V. Archontouilis, Michael J. Castellano
Plant Litter Quality Affects The Accumulation Rate, Composition, And Stability Of Mineral-Associated Soil Organic Matter, S. Carolina Córdova, Dan C. Olk, Ranae N. Dietzel, Kevin E. Mueller, Sotirios V. Archontouilis, Michael J. Castellano
Biological, Geological, and Environmental Faculty Publications
Mineral-associated organic matter (MAOM) is a relatively large and stable fraction of soil organic matter (SOM). Plant litters with high rates of mineralization (high quality litters) are hypothesized to promote the accumulation of MAOM with greater efficiency than plant litters with low rates of mineralization (low-quality litters) because litters with high rates of mineralization maximize the synthesis of microbial products and most MAOM is microbial-derived. However, the effect of litter quality on MAOM is inconsistent. We conducted four repeated short-term incubations (46-d each) of four plant litters (alfalfa, oats, maize and soybean) in two low-carbon subsoils (sandy loam and silty …
Caloric Restriction Effects On Liver Mtor Signaling Are Time‐Of‐Day Dependent, Richa Tulsian, Nikkhil Velingkaar, Roman Kondratov
Caloric Restriction Effects On Liver Mtor Signaling Are Time‐Of‐Day Dependent, Richa Tulsian, Nikkhil Velingkaar, Roman Kondratov
Biological, Geological, and Environmental Faculty Publications
The regulation of mechanistic target of rapamycin (mTOR) signaling contributes to the metabolic effects of a calorie restriction (CR) diet. We assayed the effect of CR on the activity of mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2) in the liver of mice at six different times across the day. CR effects on mTORC1 and mTORC2 activities were time-of-day dependent. CR induced mTORC1 activity at one time, reduced at two times and has no effect during other times. CR induced mTORC2 activity at one time of the day and has no effects at other times. Circadian clocks are implemented …
Modeling Habitat Of Freshwater Mussels (Bivalvia:Unionidae) In The Lower Great Lakes 25 Years After The Dreissena Invasion, Jonathan M. Bossenbroek, Lyubov E. Burlakova, Todd C. Crail, Alexander Y. Karatayev, Robert A. Krebs, David T. Zanatta
Modeling Habitat Of Freshwater Mussels (Bivalvia:Unionidae) In The Lower Great Lakes 25 Years After The Dreissena Invasion, Jonathan M. Bossenbroek, Lyubov E. Burlakova, Todd C. Crail, Alexander Y. Karatayev, Robert A. Krebs, David T. Zanatta
Biological, Geological, and Environmental Faculty Publications
Finding remnant populations of species that are of conservation concern can be difficult, particularly in aquatic habitats. Models of ecological niches can aid in the discovery of refuges. Remnant populations of native freshwater mussels (unionids) have been found in Lakes Erie and St Clair. Our goals were to predict undiscovered refuges in Lake Ontario based on habitat analysis from Lake Erie and to conduct surveys to test those predictions. We built a presence-only model on environmental data including attributes of the benthic zone and shoreline where mussels occurred in Lake Erie. We found a link between small- and large-scale variables …
Biomimetic Macromolecules For Macrophage Targeting And Modulation, Joshua Whited
Biomimetic Macromolecules For Macrophage Targeting And Modulation, Joshua Whited
ETD Archive
Carbohydrate recognition has come to the forefront of biological aiming to uncover the mechanisms of physiological and pathological processes. Cell surface glycans are involved in processes including cellular adhesion, cell signaling, and immune response. A new approach for profiling cell surface glycans has great potential for a wide range of biomedical applications. Lectins have been conventionally used to determine the structure and function of glycoproteins, however, their numbers are still restricted compared to the number of glycan structures. Boronic acid has proven a remarkable small molecule capable of binding diols in aqueous solution. This interaction indicates boronic acid derived molecules …
A Synthesis Platform For Temperature Responsive Star Polymers, Schmitt J. Richard Jr.
A Synthesis Platform For Temperature Responsive Star Polymers, Schmitt J. Richard Jr.
ETD Archive
Star polymers are a class of branched polymers comprised of several polymer chains extending from a central point. Star polymers have applications in biopharmaceuticals where they have been proposed to be suitable drug delivery vehicles. Star polymers have traditionally been synthesized through chemical synthesis with added functionality provided by grafting on the arms. This complex synthesis can be simplified by using a biosynthetic approach which enables precise control of molecular weight and composition. This approach is demonstrated using star polymers with arms composed of a temperature responsive protein-based polymer termed elastin-like polypeptide (ELP). Star polymers are characterized based on the …
The Naked Mole Rat Possesses A Differently Phased Core Clock System Along With A Different Glucose Handling And Mtor Systems Compared To The Common Lab Mouse, Soumyaditya Ghosh
The Naked Mole Rat Possesses A Differently Phased Core Clock System Along With A Different Glucose Handling And Mtor Systems Compared To The Common Lab Mouse, Soumyaditya Ghosh
ETD Archive
INTRODUCTION The Naked Mole Rat [ Heterocephalus glaber] is a type of rodent -with the highest average lifespan-30 years-among all the rodent species. It lives underground in sealed burrow systems with little to no exposure to day-night transitions on the surface. It shows polyphasic round the clock activity within its subterranean burrow system. The activity and physiology of most animals are governed by the biological circadian clock. The biological circadian clock is a system that oscillates with a rough periodicity of 24 hours. Environmental zeitgebers regulate the entrainment of the circadian clock to the 24-hour day-night cycle and light is …
Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag
Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag
ETD Archive
Kidney cyst expansion, stagnant fluid accumulation, and insufficient vascular supply can result in localized chronic ischemia-hypoxia in kidney cysts, as well as in normal renal epithelia adjacent to a cyst. We hypothesize that in normal epithelia near a cyst, the stabilization of Hypoxia Inducible Factor 1a (HIF1a), a major regulator of cellular response to hypoxia, can cause altered paracellular and transcellular transport, transforming a normal absorptive phenotype to a secretory and paracellularly leaky phenotype, leading to cyst expansion. Using 100 µmol/L cobalt chloride (CoCl2), HIF1a was stabilized in cellular nucleus of a mouse cortical collecting duct cell line (mCCD 1296 …