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Western Washington University

Salish Sea Ecosystem Conference

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Genetic And Phylogenetic Analysis Of Vibrio Parahaemolyticus Reveals Distinct Differences In Strains From The Pacific Northwest Of The U.S., Rohinee Paranjpye, Jeffery Turner, William Nilsson, Gladys Yanagida, Mark Strom May 2014

Genetic And Phylogenetic Analysis Of Vibrio Parahaemolyticus Reveals Distinct Differences In Strains From The Pacific Northwest Of The U.S., Rohinee Paranjpye, Jeffery Turner, William Nilsson, Gladys Yanagida, Mark Strom

Salish Sea Ecosystem Conference

Genetic and phylogenetic analyses of Vibrio parahaemolyticus (Vp) strains isolated from the U.S. Pacific Northwest demonstrate that clinical isolates are genetically distinct from the environmental isolates. Several environmental isolates are clonally related to strains that have been responsible for Vp-related illnesses world-wide (the pandemic complex) but have not been responsible for illnesses in the Pacific Northwest. While both clinical and a significant proportion of environmental isolates encode one of the putative virulence markers, the thermostable direct hemolysin (tdh), clinical isolates also encoded a second virulence marker, the tdh-related hemolysin (trh). Our findings suggest that V. parahaemolyticus isolates from the Pacific …