An Insight Into The Physicochemical, Drug-Likeness, Pharmacokinetics And Toxicity Profile Of Kigelia Africana (Lam) Bioactive Compounds, 2023 Department of Industrial Chemistry, Faculty of Physical Sciences, University of Ilorin, Ilorin, Nigeria
An Insight Into The Physicochemical, Drug-Likeness, Pharmacokinetics And Toxicity Profile Of Kigelia Africana (Lam) Bioactive Compounds, Sulyman Olalekan Ibrahim, Halimat Yusuf Lukman, Marili Funmilayo Zubair, Oluwagbemiga Tayo Amusan, Fatimah Ronke Abdulkadri, Bashir Lawal, Lateefat Bello Abdulfatah, Olubunmi Atolani
Al-Bahir Journal for Engineering and Pure Sciences
Kigelia africana plant is multipurpose plant whose therapeutic potential has been thoroughly investigated. The physicochemical, solubilities, ADMET, pharmacological, and drug-like properties of this plant have not been reported in details. This study makes use of the information that is currently known on the chemical make-up of the plant to forecast its overall toxicity as well as the potential for the phytochemicals it contains to be employed in medication discovery. The study also employed free web servers for the lipophilicity, water solubility, drug-likness, bioavailability score, medicinal chemistry and toxicological profiling of the compounds of K. africana. Artemether, a known antimalaria …
Promoter Effect On Carbon Nanosphere-Encapsulated Fe-Co Catalysts For Converting Co2 To Light Olefins, 2023 Rowan University
Promoter Effect On Carbon Nanosphere-Encapsulated Fe-Co Catalysts For Converting Co2 To Light Olefins, Daniel Weber, Akash Gandotra, John Schossig, Heng Zhang, Michael Wildy, Wanying Wei, Kevin Arizapana, Jin Zhong Zhang, Ping Lu, Cheng Zhang
Faculty Scholarship for the College of Science & Mathematics
For this work, we investigated the promotor effect (M = Na+, K+, Ce3+, Zn2+, Mn2+) on carbon nanosphere-encapsulated bimetallic Fe-Co core–shell catalysts for CO2 hydrogenation, promising selectivity for converting CO2 to light olefins. The fresh and spent catalysts were characterized using a combination of experimental techniques such as scanning electron microscopy (SEM), X-ray diffraction (XRD), thermogravimetric analysis and differential scanning calorimetry (TGA–DSC), and Raman spectroscopy, and our results reveal that the addition of the promotor M enhanced the formation of graphitic carbon and metal carbides in the promoted catalysts when compared with the unpromoted catalysts. The metal carbides were determined …
Coupling Chemical And Genomic Data Of Marine Sediment-Associated Bacteria For Metabolite Profiling, 2023 University of South Florida
Coupling Chemical And Genomic Data Of Marine Sediment-Associated Bacteria For Metabolite Profiling, Stephanie P. Suarez
USF Tampa Graduate Theses and Dissertations
Marine sediment-associated bacteria house many new and exciting novel secondary metabolites. These metabolites can be tested for bioactivity against various types of cancer and fungal, bacterial, and viral infections. In this thesis, we investigated the combination of biosynthetic gene cluster information with mass spectra to perform a chemical profiling of sediment- associated bacteria. Furthermore, we utilized a scoring technique to provide an identification and confidence score to each annotated compound. The sediment was collected from east Arthur Harbor, Palmer Station, Antarctica, at depths of 20 ft and 60 ft. After plating on agar, 52 unique bacterial strains were isolated, with …
Biomimetic Modifications On The Bridging Cys Residue Ligand Of An Feni Hydrogenase, 2023 Illinois State University
Biomimetic Modifications On The Bridging Cys Residue Ligand Of An Feni Hydrogenase, Madeline Kesner
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Green Synthesized Silver Nanoparticles-Based Sensing For Monitoring Water Pollution: An Updated Review, 2023 Analytical Chemistry Research Group, Chemistry Department, Institut Teknologi Bandung, Bandung, Indonesia
Green Synthesized Silver Nanoparticles-Based Sensing For Monitoring Water Pollution: An Updated Review, Muhamad Allan Serunting, Muhammad Ali Zulfikar, Henry Setiyanto, Dian Ayu Setyorini, Vienna Saraswaty
Karbala International Journal of Modern Science
Water is a basic human need and has been heavily contaminated. Therefore, it becomes a concern to remove the pollutant and monitor its quality. The removal methods include precipitation, filtration, adsorption, and photodegradation. Meanwhile, the monitoring can be done by measuring and analyzing the contaminant using spectrophotometry and chromatography. Nevertheless, those methods usually need a complicated preparation, and are expensive. Thus, a simple method is necessary to overcome these drawbacks by developing a sensor. In recent years, the sensor performance has been enhanced by using nanomaterials, such as silver nanoparticles (AgNPs). AgNPs can be synthesized using plant extracts through a …
Synthesis And Characterization Of Zirconium Oxide Nanoparticles Using Z. Officinale And S. Aromaticum Plant Extracts For Antibacterial Application, 2023 Physics Department, College of Science, University of Baghdad, Jadariya, Baghdad, Iraq
Synthesis And Characterization Of Zirconium Oxide Nanoparticles Using Z. Officinale And S. Aromaticum Plant Extracts For Antibacterial Application, M. J. Tuama, M. F. A. Alias
Karbala International Journal of Modern Science
Abstract The dramatic rise in bacterial infections and increased resistance to conventional antibiotics has led to the exploration of biologically derived nanomaterials to counteract bacterial activity. Nanotechnology, which deals with materials at the atomic or molecular level, is a promising way to achieve this goal. Zirconium oxide nanoparticles (ZrO2NPs) have shown strong antibacterial effects due to the increased surface-to-volume ratio at the nanoscale. This study focused on the production of ZrO2NPs in an environmentally friendly manner, which included extracts from Zingiber officinale (ginger), where G-ZrO2NPs were produced, and Syzygium aromaticum (clove), which produced S-ZrO2NPs. Various techniques were used, such as …
Volcanic Diffuse Volatile Emissions Tracked By Plant Responses Detectable From Space, 2023 McGill University
Volcanic Diffuse Volatile Emissions Tracked By Plant Responses Detectable From Space, Robert R. Bogue, Peter M. J. Douglas, Joshua B. Fisher, John Stix
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Volcanic volatile emissions provide information about volcanic unrest but are difficult to detect with satellites. Volcanic degassing affects plants by elevating local CO2 and H2O concentrations, which may increase photosynthesis. Satellites can detect plant health, or a reaction to photosynthesis, through a Normalized Difference Vegetation Index (NDVI). This can act as a potential proxy for detecting changes in volcanic volatile emissions from space. We tested this method by analyzing 185 Landsat 5 and 8 images of the Tern Lake thermal area (TLTA) in northeast Yellowstone caldera from 1984 to 2022. We compared the NDVI values of the thermal area with …
University Of Arkansas, Chemistry And Biochemistry Department Graduate Student Publications, 2018- November 2023. 39p., 2023 University of Arkansas, Fayetteville
University Of Arkansas, Chemistry And Biochemistry Department Graduate Student Publications, 2018- November 2023. 39p., Jeremy Smith, Lutishoor Salisbury
University Libraries Faculty Publications and Presentations
This report provides a compilation of the research publications by the Chemistry and Biochemistry (CHBC) Graduate students for the period: 2018-November 2023. It includes publications by the CHBC graduates and those where a CHBC faculty was the main advisor. It includes a summary of the research. The listing is organized according to type of publications within specific years.
University Of Arkansas, Chemistry And Biochemistry Department Research Publications, 2014- November 2023. 107p., 2023 University of Arkansas, Fayetteville
University Of Arkansas, Chemistry And Biochemistry Department Research Publications, 2014- November 2023. 107p., Jeremy Smith, Lutishoor Salisbury
University Libraries Faculty Publications and Presentations
This report provides a compilation of the research publications by the Chemistry and Biochemistry faculty for the period: 2014 - November 2023. The information was gathered from major databases in science and technology including Web of Science, SciFinder, Reaxys, PubMed, IEEE Explore and Engineering Index. At least one author in each of the publications has the CHBC department as its affiliation. It includes a table summarizing the research. The listing is organized according to type of publications within specific years.
Chapter 4.1: Visualizing The Solubility Of Salts Via 3-D Topo Surfaces: Pyramids With Ridges And Plateaus, 2023 University of Montana, Missoula
Chapter 4.1: Visualizing The Solubility Of Salts Via 3-D Topo Surfaces: Pyramids With Ridges And Plateaus, Garon C. Smith, Md Mainul Hossain
Water Topos: A 3-D Trend Surface Approach to Viewing and Teaching Aqueous Equilibrium Chemistry
A new 3-D graphical representation for the solubility of sparingly soluble salts in aqueous solutions has been developed utilizing a new composition grid. In this case, the x-axis carries the concentration of the salt’s cation (usually a metal) and the y-axis holds the concentration of the salt’s anion. Plotted above the grid are a salt’s solubility, individual species concentrations or distribution coefficients. Three levels of sophistication in the descriptive chemistry are discussed. In Case 1, the only dissolved species included are the cation and anion present in the salt’s solubility product expression, the Ksp. Case 2 …
Calorimetric Analysis Using Dna Thermal Stability To Determine Protein Concentration, 2023 Portland State University
Calorimetric Analysis Using Dna Thermal Stability To Determine Protein Concentration, Matthew W. Eskew, Patrick Reardon, Albert S. Benight
Chemistry Faculty Publications and Presentations
It was recently reported for two globular proteins and a short DNA hairpin in NaCl buffer that values of the transition heat capacities, Cp,DNA and Cp,PRO for equal concentrations (mg/mL) of DNA and proteins, are essentially equivalent (differ by less than 1%). Additional evidence for this equivalence is presented that reveals this phenomenon does not depend on DNA sequence, buffer salt, or Tm. Sequences of two DNA hairpins were designed to confer a near 20°C difference in their Tm’s. For the molecules, in NaCl and CsCl buffer the evaluated Cp,PRO and C …
Fabrication Process Independent And Robust Aggregation Of Detonation Nanodiamonds In Aqueous Media, 2023 Missouri University of Science and Technology
Fabrication Process Independent And Robust Aggregation Of Detonation Nanodiamonds In Aqueous Media, Inga C. Kuschnerus, Haotian Wen, Xinrui Zeng, Yee Yee Khine, Juanfang Ruan, Chun Jen Su, U. Ser Jeng, Hugues A. Girard, Jean Charles Arnault, Eiji Ōsawa, Olga Shenderova, Vadym Mochalin, Ming Liu, Masahiro Nishikawa
Chemistry Faculty Research & Creative Works
In the past detonation nanodiamonds (DNDs), sized 3–5 nm, have been praised for their colloidal stability in aqueous media, thereby attracting vast interest in a wide range of applications including nanomedicine. More recent studies have challenged the consensus that DNDs are monodispersed after their fabrication process, with their aggregate formation dynamics poorly understood. Here we reveal that DNDs in aqueous solution, regardless of their post-synthesis de-agglomeration and purification methods, exhibit hierarchical aggregation structures consisting of chain-like and cluster aggregate morphologies. With a novel characterization approach combining machine learning with direct cryo-transmission electron microscopy and with X-ray scattering and vibrational spectroscopy, …
Hydroxyapatite-Based Coatings On Silicon Wafers And Printed Zirconia, 2023 University of Nebraska-Lincoln
Hydroxyapatite-Based Coatings On Silicon Wafers And Printed Zirconia, Antoine Chauvin
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Dental surgery needs a naturally attract implant design that can ensure both osseointegration and soft tissue integration. Hydroxyapatite (HAp), the main mineral constituent of dentine and tooth enamel, is commonly used as a coating component, notably for overlaying titanium– or ceramics–based implants. This thesis aims to investigate the behavior of a HAp-based coating, specifically designed to be compatible with a porous substrate. Coating layers are made by sol–gel dip coating by immersion of porous substrates made by additive manufacturing into solutions of HAp, having been mixed with polyethyleneimine (PEI), to improve the adhesion of HAp on the substrate. First, the …
Cfa-Treated Mice Induce Hyperalgesia In Healthy Mice Via An Olfactory Mechanism, 2023 Oregon Health & Science University
Cfa-Treated Mice Induce Hyperalgesia In Healthy Mice Via An Olfactory Mechanism, Yangmiao Zhang, Wentai Luo, Maryt M. Heinricher, Andrey E. Ryabinin
Chemistry Faculty Publications and Presentations
Background
Social interactions with subjects experiencing pain can increase nociceptive sensitivity in observers, even without direct physical contact. In previous experiments, extended indirect exposure to soiled bedding from mice with alcohol withdrawal-related hyperalgesia enhanced nociception in their conspecifics. This finding suggested that olfactory cues could be sufficient for nociceptive hypersensitivity in otherwise untreated animals (also known as “bystanders”).
Aim
The current study addressed this possibility using an inflammation-based hyperalgesia model and long- and short-term exposure paradigms in C57BL/6J mice.
Materials & Method
Adult male and female mice received intraplantar injection of complete Freund's adjuvant (CFA) and were used as stimulus …
Oxidative Stress In Health And Disease, 2023 Missouri University of Science and Technology
Oxidative Stress In Health And Disease, V. Prakash Reddy
Chemistry Faculty Research & Creative Works
Oxidative stress, resulting from the excessive intracellular accumulation of reactive oxygen species (ROS), reactive nitrogen species (RNS), and other free radical species, contributes to the onset and progression of various diseases, including diabetes, obesity, diabetic nephropathy, diabetic neuropathy, and neurological diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). Oxidative stress is also implicated in cardiovascular disease and cancer. Exacerbated oxidative stress leads to the accelerated formation of advanced glycation end products (AGEs), a complex mixture of crosslinked proteins and protein modifications. Relatively high levels of AGEs are generated in diabetes, obesity, AD, and other …
Synthesis, Characterization, And Photophysical And Fluorescence Sensor Behaviors Of A New Water-Soluble Double-Bridged Naphthalene Diimide Appended Cyclotriphosphazene, Süreyya Oğuz Tümay, Serkan Yeşi̇lot
Turkish Journal of Chemistry
A new water-soluble template of double-bridged naphthalene diimide appended cyclotriphosphazene was prepared, and its photophysical and sensor behaviors were evaluated. The characterization of novel double-bridged naphthalene diimide appended cyclotriphosphazene (6) was carried out by NMR (1 H, 13C, 31P) and mass spectroscopies. The photophysical behaviors of compound 6 were evaluated by UV-Vis absorption and fluorescence spectroscopies in various solvent systems and different concentrations. As an application for usability of the obtained water-soluble template in different applications, the fluorescence sensor property of compound 6 was investigated in the presence of many different competing species (organic acids, saccharides, nitroaromatic compounds, anions, and …
Heterocyclic Molecules With Esipt Emission: Synthetic Approaches, Molecular Diversities, And Application Strategies, 2023 TÜBİTAK
Heterocyclic Molecules With Esipt Emission: Synthetic Approaches, Molecular Diversities, And Application Strategies, Nuretti̇n Mengeş
Turkish Journal of Chemistry
Excited-state intramolecular proton transfer (ESIPT) is one of the most essential emission processes in most circumstances because of its dual emission band in most cases and its high Stokes shifts. These distinguishing properties make ESIPT-based probes more suitable for a variety of applications, including analyte sensors, solid-state sensing mechanisms, optical technologies, and biomarkers for endogenous or exogenous compounds in various settings. As a result, researchers around the world are working on ESIPT emissions and developing different scaffolds for various applications or industry demands. This field of study is rapidly expanding and there is a need for an up-to-date review of …
Developing New Strategy Toward Ruthenium And Gold Redox Catalysis, 2023 University of South Florida
Developing New Strategy Toward Ruthenium And Gold Redox Catalysis, Chenhuan Wang
USF Tampa Graduate Theses and Dissertations
This dissertation mainly contains three parts: 1) The discovery of triazole-modified Ru carbene catalysts for alkene metathesis and dynamic covalent chemistry; 2) The study of ligand assisted gold oxidative addition toward aryl iodide to achieve the alkene difunctionalization; 3) Gold redox catalysis via chiral P,N-chelating ligands. In the first part, the 1,2,3-triazole coordinated ruthenium carbene complexes (TA-Ru) were reported for the first time as a new class of modified Grubbs catalyst to achieve challenging olefin metathesis at higher temperatures without catalyst decomposition. With this new TA-Ru catalyst, cross-metathesis (CM), ring-closing metathesis (RCM) and dynamic covalent chemistry (DCvC) were achieved. The …
Cryogelation Reactions And Cryogels: Principles And Challenges, 2023 TÜBİTAK
Cryogelation Reactions And Cryogels: Principles And Challenges, Oğuz Okay
Turkish Journal of Chemistry
Cryogelation is a powerful technique for producing macroporous hydrogels called cryogels. Although cryogelation reactions and cryogels were discovered more than 70 years ago, they attracted significant interest only in the last 20 years mainly due to their extraordinary properties compared to the classical hydrogels such as a high toughness, almost complete squeezability, a mechanically stable porous structure with honeycomb arrangement, poroelasticity, and fast responsivity against external stimuli. In this mini review, general properties of cryogelation systems including the cryoconcentration phenomenon responsible for the unique properties of the cryogels are discussed. The squeezability and poroelasticity of cryogels comparable to those seen …
Arsenic Speciation By Using Emerging Sample Preparation Techniques: A Review, 2023 TÜBİTAK
Arsenic Speciation By Using Emerging Sample Preparation Techniques: A Review, Muhammad Saqaf Jagirani, Mustafa Soylak
Turkish Journal of Chemistry
Arsenic is a hazardous element that causes environmental pollution. Due to its toxicological effects, it is crucial to quantify and minimize the hazardous impact on the ecology. Despite the significant advances in analytical techniques, sample preparation is still crucial for determining target analytes in complex matrices. Several factors affect the direct analysis, such as trace-level analysis, advanced regulatory requirements, complexity of sample matrices, and incompatible with analytical instrumentation. Along with the development in the sample preparation process, microextraction methods play an essential role in the sample preparation process. Microextraction techniques (METs) are the newest green approach that replaces traditional sample …