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Comparison Of Methods For Measuring Cation Exchange Capacity In Clays, Sarah Glaesemann 2021 Stephen F Austin State University

Comparison Of Methods For Measuring Cation Exchange Capacity In Clays, Sarah Glaesemann

Undergraduate Research Conference

No abstract provided.


Study Of Potential Drug For Alzheimer’S Disease: Small Organic Molecules, 1,5-Dhn And Tmpyp Inhibit Amyloid-Β Peptide Aggregation And Quench Hydroxyl Radicals, Matthew Murphy 2021 Stephen F Austin State University

Study Of Potential Drug For Alzheimer’S Disease: Small Organic Molecules, 1,5-Dhn And Tmpyp Inhibit Amyloid-Β Peptide Aggregation And Quench Hydroxyl Radicals, Matthew Murphy

Undergraduate Research Conference

Alzheimer disease (AD) is recognized as the six leading cause of the death in the United States. As of now, there is no cure for this fatal disease. The current treatment methods can only temporarily slow the worsening of symptoms. Research data suggested that an excess generation of hydroxyl radical in the brain causing the aggregation of Amyloid-β (Aβ) peptide which is considered to be responsible for Alzheimer's disease. Thus, there is a pressing need to find a suitable drug which can quench hydroxyl radicals effectively and stop or slow down the formation of aggregation of Aβ peptide. The ...


A Novel Molecular And Cellular Study On Curcumin, Khang Nguyen 2021 Stephen F Austin State University

A Novel Molecular And Cellular Study On Curcumin, Khang Nguyen

Undergraduate Research Conference

Since the discovery of G-quartet (G4)by M. Gellertin 1962, much attention has been given on G4and C4(also called i-motif) as important drug design targets for the treatment of various human disorders. G4 forming sequences are prevalent in human genome, which includes many important regions of the eukaryotic genome, such as telomere ends, regulatory regions of many oncogenes c-kit, proto-oncogene c-myc, Kirsten rat sarcoma viral oncogene homolog (KRas). Curcumin(diferuloylmethane), an antiinflammatory and antioxidant compound, is found in the rhizomes of the plant Curcuma longa. The phytopolyphenolic chemical curcumin has been in the prominence due to its diverse pharmacological ...


Biotransformation Of Hbe And Other Benzofuran Derivatives, Hannah Trauger 2021 Stephen F Austin State University

Biotransformation Of Hbe And Other Benzofuran Derivatives, Hannah Trauger

Undergraduate Research Conference

No abstract provided.


Synthesis Of Phosphindolizine, Tyler Bell 2021 Southern Adventist University

Synthesis Of Phosphindolizine, Tyler Bell

Campus Research Day

Synthesis of Phosphindolizine which hasn't been done before.


Chemical Leeching Of Wood Sealents, Chloe Rippey, Luke Autrey, Ellisa Gene Catahan, Stephen Hobson 2021 Liberty University

Chemical Leeching Of Wood Sealents, Chloe Rippey, Luke Autrey, Ellisa Gene Catahan, Stephen Hobson

Liberty University Research Week

Undergraduate

Basic


Greening Of Ferrocene Column Chromatography, Marissa Scilley, Anderson Hill, Michael R. Korn 2021 Liberty University

Greening Of Ferrocene Column Chromatography, Marissa Scilley, Anderson Hill, Michael R. Korn

Liberty University Research Week

Undergraduate

Basic


Synthesis Of Some Rhenium-Pyridazyl Complexes For Future Use In Semiconductive Materials, Zachariah Hutcheon, Jonathan Nelson, Philip Temple, Mark Villers, Chad Snyder 2021 Liberty University

Synthesis Of Some Rhenium-Pyridazyl Complexes For Future Use In Semiconductive Materials, Zachariah Hutcheon, Jonathan Nelson, Philip Temple, Mark Villers, Chad Snyder

Liberty University Research Week

Undergraduate

Basic


Deletion Of Ph Response Genes In Cryptococcus Neoformans, Hannah Finson, Michael S. Price 2021 Liberty University

Deletion Of Ph Response Genes In Cryptococcus Neoformans, Hannah Finson, Michael S. Price

Liberty University Research Week

Undergraduate

Basic


Design And Analysis Of A Novel Fluorescent Cell Stain, Simeon Standridge, Richard Sirard, Michael R. Korn 2021 Liberty University

Design And Analysis Of A Novel Fluorescent Cell Stain, Simeon Standridge, Richard Sirard, Michael R. Korn

Liberty University Research Week

Undergraduate

Basic


Incorporating The Origin Of Life Theme In Organic Chemistry Laboratories: Analyses Of Amino Acids, Emmalyn Sarver, Michael R. Korn 2021 Liberty University

Incorporating The Origin Of Life Theme In Organic Chemistry Laboratories: Analyses Of Amino Acids, Emmalyn Sarver, Michael R. Korn

Liberty University Research Week

Undergraduate

Basic


Nitro Group Reduction For Use In Organic, Cathodic Materials, Brock G. Goeden 2021 University of South Dakota

Nitro Group Reduction For Use In Organic, Cathodic Materials, Brock G. Goeden

Honors Thesis

The industrial demand for higher capacity, light-weight battery materials has skyrocketed in recent years due to heavy investments in portable electronics, electronic vehicles, and renewable energy sources. However, rechargeable battery technology has seen little improvement since the invention of the Lithium-Ion battery in the 1980s. The low energy density of the traditionally utilized LiCoO2 cathodic material (specific capacity: 272 mAh g-1), has limited its potential to meet these increasing demands. To solve this problem, our research group is investigating new types of lightweight, organic, polymeric materials with conductive backbones as a possible replacement for the cathodic materials in Lithium-Ion batteries ...


A Spectroscopic And Computational Study Of Diacetyl And Water Clusters, Margaret Baldwin 2021 University of Mississippi

A Spectroscopic And Computational Study Of Diacetyl And Water Clusters, Margaret Baldwin

Honors Theses

Diacetyl, otherwise known as 1,2-butadione or biacetyl, is a flavor additive used in microwave popcorn, and more importantly as of late, e-cigarettes. The compound is known to cause lung disease for those who have been exposed to a large quantity of the buttery smelling molecule. As such, the characterization of diacetyl’s vibrational modes when it interacts with water are pivotal to understanding the effects it has on human lung tissue. In this research, the intermolecular interactions between water and diacetyl and the effects they have on one another’s vibrational modes are explored. While some experimental data is ...


Developing An Experiment For General Chemistry Ii, Tyler Fisher 2021 Southern Adventist University

Developing An Experiment For General Chemistry Ii, Tyler Fisher

Campus Research Day

I am presenting on my research in figuring out how the electrochem station works for the chemistry department. My goal is to standardize the machine and then design and create an experiment for General Chemistry II Lab.


Synthesis Of Dibenzophosphole Derivatives, Allan Roy Sison 2021 Southern Adventist University

Synthesis Of Dibenzophosphole Derivatives, Allan Roy Sison

Campus Research Day

This presentation will demonstrate how dibenzophosphole derivatives are synthesized. There will also be studies on the properties of this complex compound. Our experiment is based on previous studies on dibenzophospholes. We will be using the methods from the previous studies and we will synthesize the derivatives of the dibenzophosphole compound using other compounds such as dibromophenol.


"What Lights Up Your "Tech"? - Subtitle: Synthesis Of Polycyclic Aromatic Hydrocarbons (Pah) Using To 2,2-Dibromo-1,1-Binapthalene, Jefferd Daniel 2021 Southern Adventist University

"What Lights Up Your "Tech"? - Subtitle: Synthesis Of Polycyclic Aromatic Hydrocarbons (Pah) Using To 2,2-Dibromo-1,1-Binapthalene, Jefferd Daniel

Campus Research Day

The application of this molecule can be used eventually to add several elements like (Bromine, Chlorine, etc.) Previous done research that was conducted was in shortening the process to synthesize PAH. Since then, there has been research conducted to stabilize the compound by closing/linking two of the un-linked benzene rings.

Synthesize phosphyl-paralene, functionalize, and analyze the properties of those molecules and attach its derivatives


Synthesis Of Dibenzophospholes From Biphenyl, Claudia Velasquez 2021 Southern Adventist University

Synthesis Of Dibenzophospholes From Biphenyl, Claudia Velasquez

Campus Research Day

The aim is a direct synthesis of various diphenzylphospholes using biphenyl, phosphonic acid, and Tf2O. Successful addition of the phosphonic acid in a one step reaction would result in a more efficient production of the diphenylphospholes.


Dibenzophosphole Synthesis From 4-4’-Ditertbutyl-1,1’-Biphenyl By Double C-P Bond Formation, Annette Echevarria 2021 Southern Adventist University

Dibenzophosphole Synthesis From 4-4’-Ditertbutyl-1,1’-Biphenyl By Double C-P Bond Formation, Annette Echevarria

Campus Research Day

No abstract provided.


Products Of An Acid-Catalyzed 1-Methylcyclopentene Reaction, Erin Burke 2021 Southern Adventist University

Products Of An Acid-Catalyzed 1-Methylcyclopentene Reaction, Erin Burke

Campus Research Day

The poster presents research on the alternate products produced from 1-methylcyclopentene across different concentrations of sulfuric acid catalyst.


Gcn5-Related N-Acetyltransferases (Gnats) With A Catalytic Serine Residue Can Play Ping-Pong Too, Jackson T. Baumgartner, Thahani S. Habeeb Mohammad, Mateusz P. Czub, Karolina A. Majorek, Xhulio Arolli, Cillian Variot, Madison Anonick, Wladek Minor, Miguel A. Ballicora, Daniel P. Becker Ph.D., Misty L. Kuhn 2021 San Francisco State University

Gcn5-Related N-Acetyltransferases (Gnats) With A Catalytic Serine Residue Can Play Ping-Pong Too, Jackson T. Baumgartner, Thahani S. Habeeb Mohammad, Mateusz P. Czub, Karolina A. Majorek, Xhulio Arolli, Cillian Variot, Madison Anonick, Wladek Minor, Miguel A. Ballicora, Daniel P. Becker Ph.D., Misty L. Kuhn

Chemistry: Faculty Publications and Other Works

Enzymes in the Gcn5-related N-acetyltransferase (GNAT) superfamily are widespread and critically involved in multiple cellular processes ranging from antibiotic resistance to histone modification. While acetyl transfer is the most widely catalyzed reaction, recent studies have revealed that these enzymes are also capable of performing succinylation, condensation, decarboxylation, and methylcarbamoylation reactions. The canonical chemical mechanism attributed to GNATs is a general acid/base mechanism; however, mounting evidence has cast doubt on the applicability of this mechanism to all GNATs. This study shows that the Pseudomonas aeruginosa PA3944 enzyme uses a nucleophilic serine residue and a hybrid ping-pong mechanism for catalysis ...


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