Medicine and Health Sciences Commons^™

Seroprevalence Survey Of Chikungunya Virus In Bagan Panchor, Malaysia, Chan Yoke Fun

Chan Yoke Fun

In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. One year later, a post-outbreak survey was performed to determine attack rate, asymptomatic rate, and post-infection sequelae. Findings were compared with recent CHIKV outbreaks of the Central/East African genotype. A total of 180 residents were interviewed for acute symptoms and post-infection physical quality of life and depressive symptoms. Sera from 72 residents were tested for CHIKV neutralizing antibodies. The estimated attack rate was 55.6%, and 17.5% of infected residents were asymptomatic. Arthralgia was reported up to 3 months …

Middle Cerebral Artery Occlusion Model In Rodents: Methods And Potential Pitfalls, Fudong Liu, Louise D. Mccullough

UCHC Articles - Research

A variety of animal models have been developed for modeling ischemic stroke. The middle cerebral artery occlusion (MCAO) model has been utilized extensively, especially in rodents. While the MCAO model provides stroke researchers with an excellent platform to investigate the disease, controversial or even paradoxical results are occasionally seen in the literature utilizing this model. Various factors exert important effects on the outcome in this stroke model, including the age and sex of the animal examined. This paper discusses emerging information on the effects of age and sex on ischemic outcomes after MCAO, with an emphasis on mouse models of …

Lateral Blood Flow Velocity Estimation Based On Ultrasound Speckle Size Change With Scan Velocity, Tiantian Xu, Gregory R. Bashford

Biomedical Imaging and Biosignal Analysis Laboratory

Conventional (Doppler-based) blood flow velocity measurement methods using ultrasound are capable of resolving the axial component (i.e., that aligned with the ultrasound propagation direction) of the blood flow velocity vector. However, these methods are incapable of detecting blood flow in the direction normal to the ultrasound beam. In addition, these methods require repeated pulse-echo interrogation at the same spatial location. A new method has been introduced which estimates the lateral component of blood flow within a single image frame using the observation that the speckle pattern corresponding to blood reflectors (typically red blood cells) stretches (i.e., is smeared) if the …

Wandering The Web -- To Your Good Health: Health Websites For Parents, Teens, And Kids, Carol L. Watwood

DLPS Faculty Publications

Parents, children, and teens are frequent users of health information on the Web. The Medical Library Association, the HONcode designation, and a checklist of quality indicators can be used to find and evaluate information on the Web. Some sites are designed to engage children; others are more suitable for adults or for homework assignments. A list of suggested sites is given.

Characterization Of The Sero-Reactivity Of Proteins Map1152 And Map1156 From Mycobacterium Avium Subspecies Paratuberculosis, Avery L. Paulson

Dissertations & Theses in Veterinary and Biomedical Science

Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease (JD) in ruminants. Development of genetic tools and completion of the MAP genome sequencing project expanded opportunities for antigen discovery. In this thesis, I review the current trends in diagnosis and disease control of JD and present the results of the studies on the seroreactivity of two proteins encoded for by the MAP1152-MAP1156 gene cluster. MAP1152 encodes for a PPE protein and MAP1156 encodes a diacylglycerol acyltransferase involved in triglyceride metabolism and classified in the uncharacterized protein family UPF0089. Maltose-binding protein (MBP) tagged recombinant MAP proteins were purified from Escherichia coli. Western …

Mycotoxins In Grains – Causes, Prevention And Control, Hester F. Vismer

INTSORMIL Presentations

Discusses mycotoxins, their effect on grain, mitigation considerations, and resulting human toxicology.

Stamping Out Electrosurgery Smoke, Kay Ball

Nursing Faculty Scholarship

Did you know that perioperative nurses have twice the incidence of some respiratory problems as compared to the general population? This information surprised me too when the data from my doctoral research revealed this startling and unsettling fact.....What are we breathing in the OR?

Cystic Ovaries In Dairy Cattle, Lacey Morgan Rosenberg

Dairy Science

The objective of this literature review was to determine the potential causes and factors affecting the incidence of ovarian cysts in dairy cattle as well as to examine functionality of various preventative methods and treatments of cysts. The end product was to be a document outlining all the information available on the three different types of cysts that can develop on the bovine ovary, follicular cysts, luteal cysts, and cystic corpora lutea. The literature that was reviewed, most in the forms of research papers, articles, and reviews, came primarily from scientific journals and published books. The literature reviewed was only …

Metabolic Profile Of The Ironman World Championships: A Case Study, John S. Cuddy, Dustin R. Slivka, Walter S. Hailes, Charles Dumke, Brent Ruby

Integrative Physiology and Athletic Training Faculty Publications

Purpose: The purpose of this study was to determine the metabolic profile during the 2006 Ironman World Championship in Kailua-Kona, Hawaii. Methods: One recreational male triathlete completed the race in 10:40:16. Before the race, linear regression models were established from both laboratory and field measures to estimate energy expenditure and substrate utilization. The subject was provided with an oral dose of (2)H(2)(18)O approximately 64 h before the race to calculate total energy expenditure (TEE) and water turnover with the doubly labeled water (DLW) technique. Body weight, blood sodium and hematocrit, and muscle glycogen (via muscle biopsy) were analyzed pre- and …

The Affordable Care Act, Medical Homes, And Childhood Asthma: A Key Opportunity For Progress, Meagan Lyon, Anne Rossier Markus, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

The medical homes provisions of the Affordable Care Act offer a major opportunity to advance high quality, cost-efficient health care for children with asthma. This policy brief examines evolving national medical homes policy in a childhood asthma context. Following a brief background that examines childhood asthma and explores the origins and evolution of medical homes policy (a concept developed with children in mind), the brief then describes how the Affordable Care Act can advance the implementation of medical homes policies to improve health outcomes for children with asthma.

Pharmacy Newsletter : December 2010, Pharmacy Department

Pharmacy Newsletter

Content:

• Vancomycin adverse drug reaction
• Recent FDA drug safety updates
• High risk diagnosis
• Top 10 reason for not reporting adverse drug reactions (ADRs)

Exonic Sine Insertion In Stk38l Causes Canine Early Retinal Degeneration (Erd), Orly Goldstein, Anna V. Kukekova, Gustavo D. Aguirre, Gregory M. Acland

Departmental Papers (Vet)

Fine mapping followed by candidate gene analysis of erd — a canine hereditary retinal degeneration characterized by aberrant photoreceptor development — established that the disease cosegregates with a SINE insertion in exon 4 of the canine STK38L/NDR2 gene. The mutation removes exon 4 from STK38L transcripts and is predicted to remove much of the N terminus from the translated protein, including binding sites for S100B and Mob proteins, part of the protein kinase domain, and a Thr-75 residue critical for autophosphorylation. Although known to have roles in neuronal cell function, the STK38L pathway has not previously been implicated in normal …

Eight Simple Rules For Talking With Preschoolers, Rhea Paul

Communication Disorders Faculty Publications

The article offers eight simple rules that teachers can use to help preschoolers build their vocabularies. It suggests teachers to talk with children to identify topics that interest them. It also recommends teachers to accompany all the routines and activities of the preschool day to enhance the language experience of children. Moreover, it proposes that open-ended questions invites preschoolers to offer lengthier and more detailed responses, thus stimulating their language growth.

Subsidized Housing, Public Housing, And Adolescent Violence And Substance Use, Tamara Leech

Department of Public Health Scholarship and Creative Works

This study examines the separate relationships of public housing residents and subsidized housing residence to adolescent health risk behavior. Data included 2,530 adolescents aged 14 to 19 who were children of the National the Longitudinal Study of Youth. The author uses stratified propensity methods to compare the behaviors of each group—subsidized housing residents and public housing residents—to a matched control group of teens receiving no housing assistance. The results reveal no significant relationship between public housing residence and violence, heavy alcohol/marijuana use, or other drug use. However, subsidized housing residents have significantly lower rates of violence and hard drug use, …

In Reply, Monica H. Swahn, Meltem Alemdar, Daniel J. Whitaker

Public Health Faculty Publications

A reply to a letter to the editor regarding their article:

Swahn MH, Alemdar M, Whitaker DJ. 2009. Nonreciprocal and Reciprocal Dating Violence and Injury Occurrence Among Urban Youth. The Western Journal of Emergency Medicine. 11(3):264-268.

The Economics, Opportunities, And Challenges Of Health Insurance Exchanges, Mark Duggan, Robert Kocher

Health Care Management Papers

No abstract provided.

Assessment Of Canine Best1 Variations Identifies New Mutations And Establishes An Independent Bestrophinopathy Model (Cmr3), Barbara Zangerl, Kaisa Wickström, Julianna Slavik, Sarah J. Lindauer, Saija Ahonen, Claude Schelling, Hannes Lohi, Karina E. Guziewicz, Gustavo D. Aguirre

Departmental Papers (Vet)

Purpose: Mutations in bestrophin 1 (BEST1) are associated with a group of retinal disorders known as bestrophinopathies in man and canine multifocal retinopathies (cmr) in the dog. To date, the dog is the only large animal model suitable for the complex characterization and in-depth studies of Best-related disorders. In the first report of cmr, the disease was described in a group of mastiff-related breeds (cmr1) and the Coton de Tulear (cmr2). Additional breeds, e.g., the Lapponian herder (LH) and others, subsequently were recognized with similar phenotypes, but linked loci are unknown. …

Chhs December/January E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, College Of Health And Human Services

College of Health & Human Services Publications

No abstract provided.

A Needs Assessment Of Cancer Survivors At Fox Chase Cancer Center (Abstract), Bonnie Mcintosh, Stacie Metz, Andrea Barsevick

Health Faculty Publications

No abstract provided.

Using No-Show Modeling To Improve Clinic Performance, Laura P. Sands, Joanne K Daggy, Mark Lawley, Deanna Willis, Debra Thayer, Christopher Suelzer, Po-Ching C. Delaurentis, Ayten Turkan, Santanu Chakraborty

School of Nursing Faculty Publications

‘No-shows’ or missed appointments result in under-utilized clinic capacity. We develop a logistic regression model using electronic medical records to estimate patients’ no-show probabilities and illustrate the use of the estimates in creating clinic schedules that maximize clinic capacity utilization while maintaining small patient waiting times and clinic overtime costs. This study used information on scheduled outpatient appointments collected over a three-year period at a Veterans Affairs medical center. The call-in process for 400 clinic days was simulated and for each day two schedules were created: the traditional method that assigned one patient per appointment slot, and the proposed method …