24th Asc Of Icsm Abstracts,
2022
Hong Kong College of Cardiology
24th Asc Of Icsm Abstracts
Journal of the Hong Kong College of Cardiology
No abstract provided.
The Enigma Of Primary Hypertension In Childhood,
2022
Thomas Jefferson University
The Enigma Of Primary Hypertension In Childhood, Bonita Falkner
Department of Medicine Faculty Papers
Beginning in the 1970s, hypertension in children and adolescents has been defined as systolic and/or diastolic blood pressure (BP) that is equal to or greater than the 95th percentile of the normal BP distribution in healthy children. The definition of hypertension in adults is based on longitudinal data that links a BP level with an increased risk for subsequent adverse outcomes related to hypertension including heart failure, kidney failure, stroke, or death. The statistical definition of hypertension continues to be used in childhood because there have been no data that link a BP level in childhood with a heightened risk …
Diagnostic Accuracy Of Artificial Intelligence For Detecting Gastrointestinal Luminal Pathologies: A Systematic Review And Meta-Analysis,
2022
Aga Khan University
Diagnostic Accuracy Of Artificial Intelligence For Detecting Gastrointestinal Luminal Pathologies: A Systematic Review And Meta-Analysis, Om Parkash, Asra Tus Saleha Siddiqui, Uswa Jiwani, Fahad Rind, Zahra Ali Padhani, Arjumand Rizvi, Zahra Hoodbhoy, Jai K. Das
Section of Gastroenterology
Background: Artificial Intelligence (AI) holds considerable promise for diagnostics in the field of gastroenterology. This systematic review and meta-analysis aims to assess the diagnostic accuracy of AI models compared with the gold standard of experts and histopathology for the diagnosis of various gastrointestinal (GI) luminal pathologies including polyps, neoplasms, and inflammatory bowel disease.
Methods: We searched PubMed, CINAHL, Wiley Cochrane Library, and Web of Science electronic databases to identify studies assessing the diagnostic performance of AI models for GI luminal pathologies. We extracted binary diagnostic accuracy data and constructed contingency tables to derive the outcomes of interest: sensitivity and specificity. …
A Patient Perspective On Information Provision During The Care Path Of Lentigo Maligna,
2022
Erasmus School of Health Policy and Management, Rotterdam, the Netherlands
A Patient Perspective On Information Provision During The Care Path Of Lentigo Maligna, Louis P. Ter Meer, Marleen De Mul, Jan Hazelzet, Clemens Van Eijk
Patient Experience Journal
Patients sometimes experience complex diagnostic and treatment procedures. During these processes, they need to rely on the information provided by the care providers. In particular, if they would like to play an active role in the shared decision-making process, it is important that this information is accessible, complete and understandable. A patient with Lentigo Maligna on the nose has been followed during the process of diagnosis, shared decision-making and treatment. Using the autoethnographical methodology, it was evaluated which sources of information available to the patient contributed to a better understanding, a more active role in the treatment process and a …
Living With Multiple Sclerosis As A Former Marathon Runner: Impact Of Attitude And Past Behaviour On Self-Care Maintenance And Perseverance,
2022
University of Oxford
Living With Multiple Sclerosis As A Former Marathon Runner: Impact Of Attitude And Past Behaviour On Self-Care Maintenance And Perseverance, Michael Stephanou
Patient Experience Journal
As healthcare professionals, we have a duty to promote the wellbeing of individuals living with chronic diseases and this could be accomplished through the establishment of self-care strategies that are both collaborative and self-directed. Insight into the complex behaviours and backgrounds of individuals who show initiative in dealing with chronic disease could help achieve this by revealing drivers of health-seeking and engaging behaviours. Therefore, by deducing the complex interactions between attitude, past experiences and disease outlook, broader patient welfare could be championed through the implementation of targeted interventions which promote self-care in chronic disease. This article aims to explore these …
Living With Brain Cancer: From Researcher To Patient,
2022
Florida State University College of Medicine
Living With Brain Cancer: From Researcher To Patient, Stephen P. Chelko, Daniel L. Fay Ph.D.
Patient Experience Journal
As an academic researcher, my work-life revolves around testing the efficaciousness of pharmaceutical drugs on the prevention of cardiac dysfunction, arrhythmias, and sudden cardiac death in animal models of heart disease. I never thought I would go from someone studying a life-threatening disease to a patient living with one in twenty-four hours. Yet, that transformation occurred October 8, 2019. I was just appointed to Assistant Professor at Johns Hopkins University School of Medicine (JHUSOM), yet after sitting for my professional headshot I had a grand mal seizure. I cannot recall this event, but I bit the tip of my tongue …
What Do We Know So Far About Ofatumumab For Relapsing Multiple Sclerosis? A Meta-Analytical Study,
2022
Fatima Jinnah Medical University, Pakistan
What Do We Know So Far About Ofatumumab For Relapsing Multiple Sclerosis? A Meta-Analytical Study, Hafiza Munazza Taj, Maryam Talib, Sania Siddiqa, Azza Sarfraz, Zouina Sarfraz, Karla Robles-Velasco, Ivan Cherrez-Ojeda
Department of Paediatrics and Child Health
Ofatumumab is a monoclonal antibody that reduces the level of B cells that alter the progression of relapsing multiple sclerosis. Originally approved by the Food and Drug Administration (FDA) in August 2020, this meta-analysis determines the outcomes of four randomized controlled trials (RCTs) for endline outcomes of Gadolinium-enhancing T1 lesions on MRI scans reported as Cohen's d and relapse rate reported as risk ratio. All four RCTs reported favorable findings of gadolinium-enhancing T1 lesions (Cohen's d = -0.44, p < 0.00001). The relapse rate was reduced by 46% post ofatumumab administration (RR = 0.54, p < 0.00001). With 14 ongoing trials in this area, more data is required to consolidate our findings.
Modification Of The Tumor Microenvironment Enhances Anti-Pd-1 Immunotherapy In Metastatic Melanoma,
2022
University of South Florida
Modification Of The Tumor Microenvironment Enhances Anti-Pd-1 Immunotherapy In Metastatic Melanoma, Guilan Shi, Megan Scott, Cathryn G. Mangiamele, Richard Heller
Bioelectrics Publications
Resistance to checkpoint-blockade treatments is a challenge in the clinic. Both primary and acquired resistance have become major obstacles, greatly limiting the long-lasting effects and wide application of blockade therapy. Many patients with metastatic melanoma eventually require further therapy. The absence of T-cell infiltration to the tumor site is a well-accepted contributor limiting immune checkpoint inhibitor efficacy. In this study, we combined intratumoral injection of plasmid IL-12 with electrotransfer and anti-PD-1 in metastatic B16F10 melanoma tumor model to increase tumor-infiltrating lymphocytes and improve therapeutic efficacy. We showed that effective anti-tumor responses required a subset of tumor-infiltrating CD8+ and CD4 …
Covid-19 Newsletter (Vol. 143),
2022
Touro College and University System
Covid-19 Newsletter (Vol. 143), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
The Immune System: Arthritis,
2022
Illinois Mathematics and Science Academy
The Immune System: Arthritis, Melanie Cuenca '23, Rylie Bozarth '23
Human Diseases Graphic Novels
No abstract provided.
Graphic Novel,
2022
Illinois Mathematics and Science Academy
The Digestive System,
2022
Illinois Mathematics and Science Academy
The Digestive System, Elle Brittin '23, Gwen Olney '24
Human Diseases Graphic Novels
No abstract provided.
Hashimoto's Disease,
2022
Illinois Math and Science Academy
Hashimoto's Disease, Madilyn Bulfer, Yareli Marinez, Halimat Sanusi
Human Diseases Graphic Novels
No abstract provided.
Bell's Palsy,
2022
Illinois Mathematics and Science Academy
Bell's Palsy, Munachiso Onwuameze '24, Destiny Grant '23, Kosi Okeke '24
Human Diseases Graphic Novels
No abstract provided.
Reproductive System,
2022
Illinois Mathematics and Science Academy
Reproductive System, Elle Brittin '23, Gwen Olney '24, Lily Powell '23
Human Diseases Graphic Novels
No abstract provided.
The Skeletal System – Osteoporosis,
2022
Illinois Mathematics and Science Academy
The Skeletal System – Osteoporosis, Melanie Cuenca '23, Rylie Bozarth '23
Human Diseases Graphic Novels
No abstract provided.
Asthma / Pneunomia / Cystic Acne / Eczema,
2022
Illinois Math and Science Academy
Asthma / Pneunomia / Cystic Acne / Eczema, Gabi Pride '24, Clarissa Gonzalez '24
Human Diseases Graphic Novels
No abstract provided.
Chicken Pox,
2022
Illinois Mathematics and Science Academy
Chicken Pox, Ela Gadi '23, Braeden Cullen '23, Madhav Hota '24, Alan James Anterola, Kenith Taukolo '23
Human Diseases Graphic Novels
No abstract provided.
Asthma,
2022
Illinois Mathematics and Science Academy
Asthma, Sophia Syed '23, Grace Daum '23, Shanan Riley '23, Liz Carlson '23
Human Diseases Graphic Novels
No abstract provided.
Pneumonia,
2022
Illinois Mathematics and Science Academy
Pneumonia, Munachiso Onwuameze '24, Kosi Okeke '24, Destiny Grant '23
Human Diseases Graphic Novels
No abstract provided.
