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Full-Text Articles in Social and Behavioral Sciences

Satellite Evidence For A Large Source Of Formic Acid From Boreal And Tropical Forests, T Stavrakou, J F. Muller, J Peeters, A Razavi, L Clarisse, C Clerbaux, P Coheur, D Hurtmans, M De Maziere, C Vigouroux, Nicholas Deutscher, David Griffith, Nicholas Jones, Clare Paton-Walsh Dec 2011

Satellite Evidence For A Large Source Of Formic Acid From Boreal And Tropical Forests, T Stavrakou, J F. Muller, J Peeters, A Razavi, L Clarisse, C Clerbaux, P Coheur, D Hurtmans, M De Maziere, C Vigouroux, Nicholas Deutscher, David Griffith, Nicholas Jones, Clare Paton-Walsh

Faculty of Science - Papers (Archive)

Formic acid contributes significantly to acid rain in remote environments1, 2. Direct sources of formic acid include human activities, biomass burning and plant leaves. Aside from these direct sources, sunlight-induced oxidation of non-methane hydrocarbons (largely of biogenic origin) is probably the largest source3, 4. However, model simulations substantially underpredict atmospheric formic acid levels5, 6, 7, indicating that not all sources have been included in the models. Here, we use satellite measurements of formic acid concentrations to constrain model simulations of the global formic acid budget. According to our simulations, 100–120 Tg of formic acid is produced annually, which is ...


Dietary Shiitake Mushroom (Lentinus Edodes) Prevents Fat Deposition And Lowers Triglyceride In Rats Fed A High-Fat Diet, D Handayani, J-Z Chen, Barbara J. Meyer, Xu-Feng Huang Oct 2011

Dietary Shiitake Mushroom (Lentinus Edodes) Prevents Fat Deposition And Lowers Triglyceride In Rats Fed A High-Fat Diet, D Handayani, J-Z Chen, Barbara J. Meyer, Xu-Feng Huang

Faculty of Health and Behavioural Sciences - Papers (Archive)

High-fat diet (HFD) induces obesity. This study examined the effects of Shiitake mushroom on the prevention of alterations of plasma lipid profiles, fat deposition, energy efficiency, and body fat index induced by HFD. Rats were given a low, medium, and high (7, 20, 60 g/kg = LD-M, MD-M, HD-M) Shiitake mushroom powder in their high-fat (50% in kcal) diets for 6 weeks. The results showed that the rats on the HD-M diet had the lowest body weight gain compared to MD-M and LD-M groups (P < 0.05). The total fat deposition was significantly lower (-35%, P < 0.05) in rats fed an HD-M diet than that of HFD group. Interestingly, plasma triacylglycerol (TAG) level was significantly lower (-55%, P < 0.05) in rats on HD-M than HFD. This study also revealed the existence of negative correlations between the amount of Shiitake mushroom supplementation and body weight gain, plasma TAG, and total fat masses.


Wild Type And Tangier Disease Abca1 Mutants Modulate Cellular Amyloid-Beta Production Independent Of Cholesterol Efflux Activity, Kim S. Woojin, Andrew F. Hill, Michael L. Fitzgerald, Mason W. Freeman, Genevieve Evin, Brett Garner Jan 2011

Wild Type And Tangier Disease Abca1 Mutants Modulate Cellular Amyloid-Beta Production Independent Of Cholesterol Efflux Activity, Kim S. Woojin, Andrew F. Hill, Michael L. Fitzgerald, Mason W. Freeman, Genevieve Evin, Brett Garner

Faculty of Science - Papers (Archive)

Cerebral amyloid-β (Aβ) deposition is a critical feature of Alzheimer’s disease. Aβ is derived from the amyloid-β protein precursor (AβPP) via two sequential cleavages that are mediated by β-secretase and the γ-secretase complex. Such amyloidogenic AβPP processing occurs in lipid raft microdomains of cell membranes and it is thought that modulating the distribution of lipids in rafts may regulate AβPP processing and Aβ production. Certain ATP-binding cassette (ABC) transporters regulate lipid transport across cell membranes and, as recent studies reveal, within membrane microdomains. ABCA1 also regulates Aβ metabolism in the brain although its direct impact on AβPP remains an ...


Electron Affinities, Well Depths, And Vibrational Spectroscopy Of Cis- And Trans-Hoco, Christopher J. Johnson, Michael E. Harding, Berwyck L. J Poad, John F. Stanton, Robert E. Continetti Jan 2011

Electron Affinities, Well Depths, And Vibrational Spectroscopy Of Cis- And Trans-Hoco, Christopher J. Johnson, Michael E. Harding, Berwyck L. J Poad, John F. Stanton, Robert E. Continetti

Faculty of Science - Papers (Archive)

We report vibrationally resolved photoelectron spectra of internally cold HOCO– and DOCO– anions at wavelengths near and well above the detachment threshold. These spectra are dominated by a strong Franck–Condon progression of three low-energy modes of the cis isomer, the first gas-phase measurement of these vibrations. Using highly resolved, near-threshold spectra we are able to reassign the electron affinities (EAs) of cis- and trans-HOCO to 1.51 ± 0.01 and 1.37 ± 0.01 eV, respectively. Using these EAs, well depths with respect to OH + CO are determined to be 1.07 ± 0.02 eV for trans-HOCO and 0 ...


Photoelectron-Photofragment Coincidence Spectroscopy In A Cryogenically Cooled Linear Electrostatic Ion Beam Trap, Christopher J. Johnson, Ben B. Shen, Berwyck L. J Poad, Robert E. Continetti Jan 2011

Photoelectron-Photofragment Coincidence Spectroscopy In A Cryogenically Cooled Linear Electrostatic Ion Beam Trap, Christopher J. Johnson, Ben B. Shen, Berwyck L. J Poad, Robert E. Continetti

Faculty of Science - Papers (Archive)

A cryogenically cooled linear electrostatic ion beam trap for use in photoelectron-photofragment coincidence (PPC) spectroscopy is described. Using this instrument, anions created in cold, low-dutycycle sources can be stored for many seconds in a ∼20 K environment to cool radiatively, removing energetic uncertainties due to vibrationally excited precursor anions. This apparatus maintains a well-collimated beam necessary for high-resolution fragment imaging and the high experimental duty cycle needed for coincidence experiments. Ion oscillation is bunched and phase-locked to a modelocked laser, ensuring temporal overlap between ion bunches and laser pulses and that ions are intersected by the laser only when travelling ...


Rotationally Resolved Infrared Spectrum Of The Na+-D2 Complex: An Experimental And Theoretical Study, Berwyck L. Poad, V Dryza, J Klos, A A. Buchachenko, E J. Bieske Jan 2011

Rotationally Resolved Infrared Spectrum Of The Na+-D2 Complex: An Experimental And Theoretical Study, Berwyck L. Poad, V Dryza, J Klos, A A. Buchachenko, E J. Bieske

Faculty of Science - Papers (Archive)

The infrared spectrum of mass-selected Na+-D2 complexes is recorded in the D-D stretch vibration region (2915-2972 cm−1) by detecting Na+ photofragments resulting from photo-excitation of the complexes. Analysis of the rotationally resolved spectrum confirms a T-shaped equilibrium geometry for the complex and a vibrationally averaged intermolecular bond length of 2.461 Å. The D-D stretch band centre occurs at 2944.04 cm−1, representing a −49.6 cm−1 shift from the Q1(0) transition of the free D2 molecule. Variational rovibrational energy level calculations are performed for Na+-D2 utilising an ab initio potential energy surface developed ...


Corrigendum To ‘‘The Chaperone Action Of Bovine Milk As1- And As2-Caseins And Their Associated Form As-Casein’’ [Arch. Biochem. Biophys. 510 (2011) 42–52], Teresa M. Treweek, David C. Thorn, William E. Price, John A. Carver Jan 2011

Corrigendum To ‘‘The Chaperone Action Of Bovine Milk As1- And As2-Caseins And Their Associated Form As-Casein’’ [Arch. Biochem. Biophys. 510 (2011) 42–52], Teresa M. Treweek, David C. Thorn, William E. Price, John A. Carver

Faculty of Science - Papers (Archive)

No abstract provided.


Reactions Of Simple And Peptidic Alpha-Carboxylate Radical Anions With Dioxygen In The Gas Phase, Tony Ly, Benjamin B. Kirk, Pramesh I. Hettiarachchi, Berwyck L. Poad, Adam J. Trevitt, Gabriel Da Silva, Stephen J. Blanksby Jan 2011

Reactions Of Simple And Peptidic Alpha-Carboxylate Radical Anions With Dioxygen In The Gas Phase, Tony Ly, Benjamin B. Kirk, Pramesh I. Hettiarachchi, Berwyck L. Poad, Adam J. Trevitt, Gabriel Da Silva, Stephen J. Blanksby

Faculty of Science - Papers (Archive)

α-Carboxylate radical anions are potential reactive intermediates in the free radical oxidation of biological molecules (e.g., fatty acids, peptides and proteins). We have synthesised well-defined α-carboxylate radical anions in the gas phase by UV laser photolysis of halogenated precursors in an ion-trap mass spectrometer. Reactions of isolated acetate (CH2CO 2-) and 1-carboxylatobutyl (CH3CH 2CH2CHCO2-) radical anions with dioxygen yield carbonate (CO3-) radical anions and this chemistry is shown to be a hallmark of oxidation in simple and alkyl-substituted cross-conjugated species. Previous solution phase studies have shown that Cα-radicals in peptides, formed from free radical damage, combine with dioxygen to ...


Rocky Intertidal Temperature Variability Along The Southeast Coast Of Australia: Comparing Data From In Situ Loggers, Satellite-Derived Sst And Terrestrial Weather Stations, Justin Adam Lathlean, David J. Ayre Prof, Todd E. Minchinton Jan 2011

Rocky Intertidal Temperature Variability Along The Southeast Coast Of Australia: Comparing Data From In Situ Loggers, Satellite-Derived Sst And Terrestrial Weather Stations, Justin Adam Lathlean, David J. Ayre Prof, Todd E. Minchinton

Faculty of Science - Papers (Archive)

Predicting how both spatial and temporal variation in sea and air temperature influence the distribution of intertidal organisms is a pressing issue. We used data from satellites, weather stations and in situ loggers to test the hypothesis that satellite-derived sea surface temperatures (SSTs) and weather station air temperatures provide accurate estimates of ambient temperature variability on rocky intertidal shores for temporal (hourly for 1 yr) and spatial (10 m to 400 km) variation along the southeast coast of Australia. We also tested whether satellites and weather stations accurately detect the duration, frequency and number of extreme temperature events. Daily mean ...


Significance Of P2x7 Receptor Variants To Human Health And Disease, Ronald Sluyter, Leanne Stokes Jan 2011

Significance Of P2x7 Receptor Variants To Human Health And Disease, Ronald Sluyter, Leanne Stokes

Faculty of Science - Papers (Archive)

The human P2X7 receptor is a trimeric ligand-gated cation channel coded by the P2RX7 gene located at chromosome position 12q24. P2X7 is expressed in a wide variety of normal and disease-associated cell types. Activation of this receptor by extracellular adenosine 5’-triphosphate results in numerous downstream events including the release of pro-inflammatory mediators, cell proliferation or death, and killing of intracellular pathogens. As a result, P2X7 plays important roles in inflammation, immunity, bone homeostasis, neurological function and neoplasia. The P2RX7 gene encodes a P2X7 subunit 595 amino acids in length, however splice isoforms that can alter receptor expression and function ...


Alunite Formation Within Silica Stalactites From The Sydney Region, South-Eastern Australia, Robert A. Wray Jan 2011

Alunite Formation Within Silica Stalactites From The Sydney Region, South-Eastern Australia, Robert A. Wray

Faculty of Science - Papers (Archive)

"This paper presents X-ray diffraction and SEM evidence for the formation of alunite, and possibly small quantities of natroalunite, within opal-A stalactites formed on quartz sandstone near Sydney in south-eastern, Australia. Alunite has been reported as a speleogenetic mineral from sediments within a number of caves around the world, but this is believed to be the first report of speleothemic alunite in opaline silica speleothems. Individual alunite crystals have not been visually identified, but SEM X-ray element mapping suggests the alunite has formed amongst kaolinite clay. Sedimentary alunite and natroalunite formation is usually associated with the reaction of sulphuric acid ...


Phylum Arthropoda, Subphylum Trilobitomorpha: Trilobites, Anthony J. Wright, Roger A. Cooper Jan 2011

Phylum Arthropoda, Subphylum Trilobitomorpha: Trilobites, Anthony J. Wright, Roger A. Cooper

Faculty of Science - Papers (Archive)

This volume is the second of three that provide a complete review and inventory of New Zealand's entire living and fossil biodiversity - an international effort involving more than 220 New Zealand and overseas specialists and the most comprehensive of its kind in the world. Together, the three volumes will list every one of the almost 55,000 known species of New Zealand's animals, plants, fungi and micro-organisms. Volume 2 mostly deals with the major branch of the animal kingdom known as Ecdysozoa (moulting animals), which includes arachnids, centipedes and millipedes, crustaceans and insects. It also includes the enigmatic ...


Spectroscopic And Computational Study Of Β-Ethynylphenylene Substituted Zinc And Free-Base Porphyrins, John C. Earles, Keith C. Gordon, Adam W. I Stephenson, Ashton C. Partridge, David L. Officer Jan 2011

Spectroscopic And Computational Study Of Β-Ethynylphenylene Substituted Zinc And Free-Base Porphyrins, John C. Earles, Keith C. Gordon, Adam W. I Stephenson, Ashton C. Partridge, David L. Officer

Faculty of Science - Papers (Archive)

A series of tetraphenylporphyrins appended at the β-pyrrolic position with an ethynylphenylene- or ethynylpyridine-substituent have been subjected to spectroscopic and density functional theory (DFT) analyses. The mean absolute deviation between corresponding experimental and DFT-derived vibrational spectra is up to 10.2 cm -1, suggesting that the DFT B3LYP/6-31G(d) method provides an accurate model of the β-substituted porphyrin systems. The configuration interactions that give rise to prominent electronic absorptions have been calculated using time-dependant DFT (TD-DFT) and have been rationalized with reference to the energy and topology of DFT calculated molecular orbitals. As the electron withdrawing capacity of the ...


Soils Of Low Elevation Coral Structures, John Morrison Jan 2011

Soils Of Low Elevation Coral Structures, John Morrison

Faculty of Science - Papers (Archive)

The small islands of the South Pacific region, like many other parts of the world, arc (~\I\j riencing population growth and, more particularly, the movement of people into )11,1I1!1 urban centres. Most Pacific cities, especially the capitals of regional countries, arc locili ",I in naturally protected coastal waterways. This is a historical situation, arising from III,' need to provide protected deep-water harbours for ships, the main form of internaliol\,d travel and trade. These waters are protected by offshore barrier reefs, by islands or by ril(,1 ine deltas. However, these protective mechanisms also have the effect ...


The Moral Terrains Of Ecotourism And The Ethics Of Consumption, Robert Melchior Figueroa, Gordon R. Waitt Jan 2011

The Moral Terrains Of Ecotourism And The Ethics Of Consumption, Robert Melchior Figueroa, Gordon R. Waitt

Faculty of Science - Papers (Archive)

In this chapter, we provide a brief overview of Western philosophical ethics as they may peliain to tourism. Our discussion then turns to one of the most popular attempts to address sustainability across the globe: ecotourism. Ecotourism as distinct from tourism writ large is earmarked by appeals to concepts and ethical practices peliaining to sustainability (in all its varied meanings), consumption, preservation, and the politics of colonialism and the dynamics of global development strategies. In order to bring the ethics of consumption into the context of ecotourism, we provide a case account of ecotourism that represents one of the more ...


Electronic Interactions Within Composites Of Polyanilines Formed Under Acidic And Alkaline Conditions. Conductivity, Esr, Raman, Uv-Vis And Fluorescence Studies, L Dennany, P C. Innis, S T. Mcgovern, Gordon G. Wallace, Robert J. Forster Jan 2011

Electronic Interactions Within Composites Of Polyanilines Formed Under Acidic And Alkaline Conditions. Conductivity, Esr, Raman, Uv-Vis And Fluorescence Studies, L Dennany, P C. Innis, S T. Mcgovern, Gordon G. Wallace, Robert J. Forster

Faculty of Science - Papers (Archive)

The properties of two forms of polyaniline (PAni) synthesised under acidic and basic conditions have been investigated both individually and as combined complexes. The PAni polymerised within alkaline media was redox inactive and non-conducting while the PAni emeraldine salt (ES) was electroactive and conducting. Raman, electron spin resonance, UV-Vis and fluorescence spectroscopies were used to monitor the changes in electronic properties of these conducting polymer composites. Solution cast films of alkaline synthesised (A-PAni) with the PAni ES resulted in an increase in the high spin polaron population suggesting that it acts as a pseudodopant. The ability of the A-PAni to ...


Paleoclimate From Corals, Helen V. Mcgregor Jan 2011

Paleoclimate From Corals, Helen V. Mcgregor

Faculty of Science - Papers (Archive)

Ocean- atmosphere interactions in the tropics have farreaching conscqucnccs for climate variabi lity across the globe. The tropics drive heat transfer to the poles, and tropical inter-annual oscillations such as the El Nino-Southern Oscillation (ENSO) and Indian Ocean dipole (IOD), via atmospheric tcleconncctions, affcct rain rail patterns and climate conditions in arcas far bcyond the tropics (Ropelewski and Halpert, 1987), causing major socioeconomic impacts. Monitoring eIT0l1s have focused on improving obscrvations and undcrstanding of tropical climate variability, with the view to refining modeling or the tropical oceans and atmosphere. Despite these efforts, most instrumcntal records span only the past few ...


Conclusion: Tackling The 'Missing Scale' In Environmental Policy, Ruth Lane, Andrew W. Gorman-Murray Jan 2011

Conclusion: Tackling The 'Missing Scale' In Environmental Policy, Ruth Lane, Andrew W. Gorman-Murray

Faculty of Science - Papers (Archive)

The foregoing chapters have demonstrated that household sustainability is a complex issue that requires thoughtful discussion from multiple perspectives. Indeed throughout this collection we have encouraged a dialogical approach. On the one hand our aim has been to bring researchers from human geography and cultural studies into a productive dialogue around the material geographies of household sustainability. There has been enthusiastic cross-fertilisation of ideas and approaches shown through the chapters, which critically develop the interconnections between the material, socia-technical, culturaJ, embodied and political dimensions which make households function, with particular attention to how they (might) function in environmentally sustainable ways ...


Synthesis Of Novel Sugar Diamino Acids, M Thillakan, A Katsifis, D Skropeta Jan 2011

Synthesis Of Novel Sugar Diamino Acids, M Thillakan, A Katsifis, D Skropeta

Faculty of Science - Papers (Archive)

Sugar amino acids (SAAs) are found in nature as good construction elements for the preparation of peptide mimetics and oiigosaccharides in drug design and development. The synthesis of SAAs is readily accomplished in few steps and more than 40 SAAs have been synthesised to date.2 Sugar amino acids with an additional amino group, the sugar diamino acid (SDAs) would represent a useful expansion to the library of SAAs available because one of the amino group and carboxylic acid is available for peptide coupling and the another amino/azide group allow to do further derivatisation via peptide or click chemistry ...


Reappraising The Role Of Suburban Workplaces In Darwin's Creative Economy, Chris Brennan-Horley Jan 2011

Reappraising The Role Of Suburban Workplaces In Darwin's Creative Economy, Chris Brennan-Horley

Faculty of Science - Papers (Archive)

Traditionally, suburbs have been conceived as dormitory – in binary opposition to the inner-city (Powell). Supporting this stereotypical view have been gendered binaries between inner and outer city areas; densely populated vs. sprawl; gentrified terraces and apartment culture vs. new estates and first home buyers; zones of (male) production and creativity against (female) sedate, consumer territory. These binaries have for over a decade been thoroughly criticised by urban researchers, who have traced such representations and demonstrated how they are discriminatory and incorrect (see Powell; Mee; Dowling and Mee). And yet, such binaries persist in popular media commentaries and even in academic ...


Preliminary Assessment Of The Handline (Banca) Fisheries In The Philippines (Fis/2009/033). Final Report, Ronald J. West, Mary Ann Palma, Noel Barut, Elaine Garvilles, Desiderio Ayanan Jan 2011

Preliminary Assessment Of The Handline (Banca) Fisheries In The Philippines (Fis/2009/033). Final Report, Ronald J. West, Mary Ann Palma, Noel Barut, Elaine Garvilles, Desiderio Ayanan

Faculty of Science - Papers (Archive)

The Philippines, with an Exclusive Economic Zone (EEZ) of 2.2 million sq. km, including over 7,000 islands, relies on fisheries as one of its major industries, sources of employment and in promoting food security. The hand-line fishery using bancas (or pump boats), catching commercially viable species such as tuna, is a major component of both municipal and commercial fisheries in the Philippines. Hand-line fishing is considered one of the most sustainable forms of fishing in the country. However, the economic significance of the hand-line fishery is increasingly threatened by a number of factors, including poor information on the ...


Membrane Biological Reactors, F I. Hai, K Yamamoto Jan 2011

Membrane Biological Reactors, F I. Hai, K Yamamoto

Faculty of Science - Papers (Archive)

Membrane biological reactors combine the use of biological processes and membrane technology to treat wastewater. The use of biological treatment can be traced back to the late nineteenth century. It became a standard method of wastewater treatment by the 1930s (Rittmann, 1987). Both aerobic and anaerobic biological treatment methods have been extensively used to treat domestic and industrial wastewater (Visvanathan et al., 2000). After removal of the soluble biodegradable matter in the biological process, any biomass formed needs to be separated from the liquid stream to produce the required effluent quality. In the conventional process, a secondary settling tank is ...


Preparation And Characterisation Of Conducting Biopolymer-Carbon Nanotube Composite Materials, Ali Aldalbahi, Marc In Het Panhuis Jan 2011

Preparation And Characterisation Of Conducting Biopolymer-Carbon Nanotube Composite Materials, Ali Aldalbahi, Marc In Het Panhuis

Faculty of Science - Papers (Archive)

In this work, kappa-carrageenan (KC) is used to prepare composite dispersions consisting of single-walled (SWNTs) and multi-walled (MWNTs) carbon nanotubes. Free-standing composite films were prepared by evaporative casting and vacuum filtration of these dispersions.


Unmanned Aerial Vehicle (Uav) Remote Sensing For Hyperspatial Terrain Mapping Of Antarctic Moss Beds Based On Structure From Motion (Sfm) Point Clouds, A Lucieer, Sharon A. Robinson, D Turner Jan 2011

Unmanned Aerial Vehicle (Uav) Remote Sensing For Hyperspatial Terrain Mapping Of Antarctic Moss Beds Based On Structure From Motion (Sfm) Point Clouds, A Lucieer, Sharon A. Robinson, D Turner

Faculty of Science - Papers (Archive)

This study is the first to use an Unmanned Aerial Vehicle (UAV) for mapping moss beds in Antarctica. Mosses can be used as indicators for the regional effects of climate change. Mapping and monitoring their extent and health is therefore important. UAV aerial photography provides ultra-high resolution spatial data for this purpose. The aim of this study is to use Structure from Motion (SfM) techniques to generate a detailed 3D point cloud of the terrain from overlapping UAV photography.


Phytochemical Studies On Stemona Aphylla: Isolation Of A New Stemofoline Alkaloid And Six New Stemofurans, Thanapat Sastraruji, Sukanda Chaiyong, Araya Jatisatienr, Stephen G. Pyne, Alison T. Ung, Wilford Lie Jan 2011

Phytochemical Studies On Stemona Aphylla: Isolation Of A New Stemofoline Alkaloid And Six New Stemofurans, Thanapat Sastraruji, Sukanda Chaiyong, Araya Jatisatienr, Stephen G. Pyne, Alison T. Ung, Wilford Lie

Faculty of Science - Papers (Archive)

A new stemofoline alkaloid, (2′S)-hydroxy-(11S,12R)-dihydrostemofoline (3), new stemofurans M-R (8-13), and known compounds stemofoline (1), (2′S)-hydroxystemofoline (2), stemofuran E (4), stemofuran F (5), stemofuran J (6), and stilbostemin F (7) have been isolated from the root extracts of Stemona aphylla. The structures and relative configurations of these new compounds have been determined by spectroscopic data interpretation and from semisynthetic studies. These natural and semisynthetic alkaloids were tested for acetylcholinesterase inhibitory activities and were found to be 10-20 times less active than 1′,2′-didehydrostemofoline itself. Stemofurans 4, 6, 8, 11, and 13 were ...


Influence Of Salicylic Acid On Alkaloid Production By Root Cultures Of Stemona Curtisii Hook. F., K. Chotikadachanarong, S. Dheeranupattana, Chaiwat Jatisatienr, S. Wangkarn, Pitchaya Mungkornasawakul, Stephen G. Pyne, Alison T. Ung, Thanapat Sastraruji Jan 2011

Influence Of Salicylic Acid On Alkaloid Production By Root Cultures Of Stemona Curtisii Hook. F., K. Chotikadachanarong, S. Dheeranupattana, Chaiwat Jatisatienr, S. Wangkarn, Pitchaya Mungkornasawakul, Stephen G. Pyne, Alison T. Ung, Thanapat Sastraruji

Faculty of Science - Papers (Archive)

To enhance the production of oxyprotostemonine, stemocurtisine and stemocurtisinol (the important insecticidal alkaloids) by root cultures of Stemona curtisii Hook. F. (Thai vernacular, Non Tai Yak, Family Stemonaceae). The roots were cultured on semi-solid MS medium containing 1 mg/L NAA with different concentrations of salicylic acid for 16 weeks. The quantity of the individual alkaloids was determined by HPLC. The highest production of oxyprotostemonine (7.192 mg/g dw), stemocurtisine (0.039 mg/g dw) and stemocurtisinol (0.197 mg/g dw) occurred when the roots were stimulated by 500 mg/L salicylic acid.


Understanding The Α-Crystallin Cell Membrane Conjunction, Shih-Ping Su, Jason D. Mcarthur, Michael G. Friedrich, Roger J. W Truscott, J. A. Aquilina Jan 2011

Understanding The Α-Crystallin Cell Membrane Conjunction, Shih-Ping Su, Jason D. Mcarthur, Michael G. Friedrich, Roger J. W Truscott, J. A. Aquilina

Faculty of Science - Papers (Archive)

PURPOSE. It is well established that levels of soluble α-crystallin in the lens cytoplasm fall steadily with age, accompanied by a corresponding increase in the amount of membrane-bound α-crystallin. Less well understood, is the mechanism driving this age-dependent membrane association. The aim of this study was to investigate the role of the membrane and its associated proteins and peptides in the binding of α-crystallin.

METHODS. Fibre cell membranes from human and bovine lenses were separated from soluble proteins by centrifugation. Membranes were stripped of associated proteins with successive aqueous, urea and alkaline solutions. Protein constituents of the respective membrane isolates ...


Revealing Indigenous Indonesian Traditional Medicine: Anti-Infective Agents, Paul A. Keller, Ari Satia Nugraha Jan 2011

Revealing Indigenous Indonesian Traditional Medicine: Anti-Infective Agents, Paul A. Keller, Ari Satia Nugraha

Faculty of Science - Papers (Archive)

Indonesia is rich in medicinal plants which the population has used traditionally from generation to generation for curing diseases. Our interest in the treatment of infectious diseases has lead to the investigation of traditional Indonesian treatments. In this review, we present a comprehensive review of ethnopharmacologically directed screening in Indonesian medicinal plants to search for new anti-viral, antimalarial, anti-bacterial and anti-fungal agents. Some potent drug leads have been isolated from Indonesian medicinal plants. Further research is still required for the lead development as well as the search for new bioactive compounds from the enormous medicinal plant resources.


Isolation Of Linobiflavonoid, A Novel Biflavonoid From Linostoma Pauciflorum Griff, Tawesin Navarat, Stephen G. Pyne, Uma Prawat, Pittaya Tuntiwachwuttikul Jan 2011

Isolation Of Linobiflavonoid, A Novel Biflavonoid From Linostoma Pauciflorum Griff, Tawesin Navarat, Stephen G. Pyne, Uma Prawat, Pittaya Tuntiwachwuttikul

Faculty of Science - Papers (Archive)

A novel biflavonoid, that we have named linobiflavonoid, and the known biscoumarin ether, daphnoretin, were isolated from the root extracts of Linostoma pauciflorum Griff. The structure of linobiflavonoid was determined from interpretation of its NMR spectroscopic data and from a comparison of this data with those of known biflavonoids and biflavones. The known flavones, 5,4'-dihydroxy- 7,3',5'-trimethoxyflavone and 5,4'-dihydroxy-7-methoxyflavone along with stigmasterol were isolated from the vines of the same plant. 4'-Dihydroxy-7,3'-5'-trimethoxyflavone was active against Mycobacterium tuberculosis (MIC 3.13 mu M) and KB-oral cavity cancer (IC50 17.41 ...


Identification Of Phospholipids In Human Meibum By Nano-Electrospray Ionisation Tandem Mass Spectrometry, Jennifer T. Saville, Zhenjun Zhao, Mark Dp Willcox, Manjula A. Ariyavidana, Stephen J. Blanksby, Todd W. Mitchell Jan 2011

Identification Of Phospholipids In Human Meibum By Nano-Electrospray Ionisation Tandem Mass Spectrometry, Jennifer T. Saville, Zhenjun Zhao, Mark Dp Willcox, Manjula A. Ariyavidana, Stephen J. Blanksby, Todd W. Mitchell

Faculty of Science - Papers (Archive)

Meibum is believed to be the major source of tear !lm lipids, which are vital in the prevention of excessevaporation of the aqueous phase. The complete lipid composition of meibum has yet to be established.While earlier studies reported the presence of phospholipids in human meibum, recent mass spectrometricstudies have not detected them. In this study we use electrospray ionisation tandem massspectrometry to investigate the presence of phospholipids in meibum and provide comparison to thephospholipid pro!le of tears.Lipids were extracted from human meibum and tear samples using standard biphasic methods andanalysed by nano-electrospray ionisation tandem mass spectrometry using ...