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Full-Text Articles in Social and Behavioral Sciences
Analysis Of Health Care Costs Over A One-Year Period Following Anticoagulant Therapy Among Ontario Patients Diagnosed With Atrial Fibrillation, Michael Situ
Electronic Thesis and Dissertation Repository
Atrial fibrillation patients are at high risk of ischemic strokes, which can be drastically reduced using oral anticoagulants (OACs). Warfarin has been the standard OAC for this population but its effectiveness rests on consistent monitoring with the potential for severe bleeding events. Newer OACs, like rivaroxaban and apixaban, address these drawbacks but have a comparatively higher upfront cost. Uncertainty remains over which OAC is cost-saving from a health care system perspective. Using a retrospective cohort study design and inverse probability weighting regression adjustment estimators, one-year health care costs among patients treated with warfarin, rivaroxaban, and apixaban were compared. Compared to …
Financial Costs Incurred By Living Kidney Donors: Findings From A Canadian Multi-Centre Prospective Cohort Study, Sebastian Przech
Financial Costs Incurred By Living Kidney Donors: Findings From A Canadian Multi-Centre Prospective Cohort Study, Sebastian Przech
Electronic Thesis and Dissertation Repository
This prospective cohort study across 12 Canadian transplant centres evaluated the costs incurred by 912 living kidney donors. Expenses and resources were captured to 3-months post-donation, and micro-costing was used to appraise the costs incurred by donors. Living kidney donors incurred average total costs of $4790, and direct and indirect costs of $2110 and $2679, respectively. 13.3% of donors incurred total costs exceeding $10,000, and 8.6% of donors incurred costs >25% of their annual household income. Costs incurred by spousal donors were not significantly different from either unrelated or closely related donors. Similarly, costs incurred by kidney paired donors were …
A Comparison Of Clinical Trial And Model-Based Cost Estimates In Glaucoma – The Case Of Repeat Laser Trabeculoplasty In Ontario, Omar Akhtar
Electronic Thesis and Dissertation Repository
Background and objective: For cost-effectiveness analyses (CEA) of glaucoma interventions to be of use they require valid and accurate cost and effectiveness data. Costs remain understudied relative to effectiveness. The impact of cost estimation methods on resultant estimates is unknown in glaucoma. Direct measurement of costs is labour-intensive and expensive. Decision-analytic modelling of costs using literature sources, expert opinion, institutional experience and assumptions provides a quicker, less laborious alternative to empirical costing. A lack of long-term effectiveness data in chronic diseases like glaucoma means that modelling is widespread and inevitable, both for CEAs and budget impact projections. The same problem …