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Social and Behavioral Sciences Commons™
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University of Tennessee, Knoxville
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
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Full-Text Articles in Social and Behavioral Sciences
The Effects Of Relationships On Ans Function And Wellness, Olivia M. Maples
The Effects Of Relationships On Ans Function And Wellness, Olivia M. Maples
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
The quality of relationships and social networks plays a vital role on well-being (Feeney & Collins, 2015). Social support is linked to positive biological profiles in that social support protects against the negative effects of changes in cardiovascular, neuroendocrine, and immune function. Furthermore, when exploring Autonomic Nervous System (ANS) function, higher heart rate variability has been shown to reflect a psychophysiological state compatible with social interaction (Quintana, Guastella, Outhred, Hickie, & Kemp, 2012). Social support has been shown to buffer against the negative effects of life stressors (Cohen & Wills, 1985), and ultimately, mortality (Holt-Lunstad, Smith, & Layton, 2010). In …
Acute Social Defeat-Induced Neuroinflammation In The Vmpfc Of Syrian Hamsters Via Microglial Activation, Thomas Clarity
Acute Social Defeat-Induced Neuroinflammation In The Vmpfc Of Syrian Hamsters Via Microglial Activation, Thomas Clarity
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
Research suggests causal relationships between neuroinflammation and stress-related psychopathologies. Exposure to moderate or chronic psychological stress in rodents leads to increased activation of microglia, the brain’s resident immune cells. The ventral medial prefrontal cortex (vmPFC) is a key limbic region involved in top-down regulation of psychological stress and mediates the deleterious effects of microglial activity following prolonged restraint stress. While there is a growing body of literature indicating that chronic social defeat increases microglial activity in the vmPFC, there has been little research investigating the effects of acute social defeat stress. Here, we used an acute social defeat paradigm in …