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Social and Behavioral Sciences Commons™
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University of Arkansas, Fayetteville
Inquiry: The University of Arkansas Undergraduate Research Journal
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Sequence Analysis Of The Angiotensin Ii Type 1 Receptor (Agtr1) Gene For Mutations Contributing To Pulmonary Hypertension In The Chicken (Gallus Gallus), John Russell Burks
Sequence Analysis Of The Angiotensin Ii Type 1 Receptor (Agtr1) Gene For Mutations Contributing To Pulmonary Hypertension In The Chicken (Gallus Gallus), John Russell Burks
Inquiry: The University of Arkansas Undergraduate Research Journal
Our multidisciplinary group at the University of Arkansas has been investigating the suitability of the chicken as a medical model for pulmonary arterial hypertension (PAH) in humans. There are several forms of PAH in humans arising from elevated pulmonary arterial pressure and pulmonary vascular resistance. Spontaneous cases of PAH are known as idiopathic PAH (IPAH), where the exact physiological causes are not known. IPAH patients that do not respond to standard treatments have a prognosis of only a few years. Currently, there is no acceptable animal model for IPAH. As part of our effort to pursue the chicken as model …