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Full-Text Articles in Optics

Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost Dec 2023

Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost

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In confocal single-molecule FRET experiments, the joint distribution of FRET efficiency and donor lifetime distribution can reveal underlying molecular conformational dynamics via deviation from their theoretical Forster relationship. This shift is referred to as a dynamic shift. In this study, we investigate the influence of the free energy landscape in protein conformational dynamics on the dynamic shift by simulation of the associated continuum reaction coordinate Langevin dynamics, yielding a deeper understanding of the dynamic and structural information in the joint FRET efficiency and donor lifetime distribution. We develop novel Langevin models for the dye linker dynamics, including rotational dynamics, based …


Radiation Exposure Calibration Of The Al2o3:C With Radium-226 And Cesium-137 Using The Osl Method, Selma Tepeli Aydin Dec 2023

Radiation Exposure Calibration Of The Al2o3:C With Radium-226 And Cesium-137 Using The Osl Method, Selma Tepeli Aydin

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Optically stimulated luminescence (OSL) dosimetry was utilized to calibrate Al2O3:C powder dosimeters, available commercially as the nanoDot® from Landauer Inc., and compare the dosimeter response to radium-226 (226Ra) and cesium-137 (137Cs). The signal from the OSL was quantified using a microSTARii® OSL reader also produced by Landauer Inc. Dose-response curves were developed for 226Ra and 137Cs experiments (5 dosimeters each) at thirteen absorbed doses. Individual dosimeter response was tracked by serial number. Linear regression analysis was performed to determine if there were significant differences between the intercepts of the …


Hybridly Integrated Semiconductor Lasers And Amplifiers On Iii-V/Si3n4 Platform For Beam Combining And Other Advanced Applications, Siwei Zeng Aug 2023

Hybridly Integrated Semiconductor Lasers And Amplifiers On Iii-V/Si3n4 Platform For Beam Combining And Other Advanced Applications, Siwei Zeng

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Photonic integrated circuits (PICs) are devices that integrate multiple photonic functions on a small chip and allow for accurate dimension control and massive production. Similar to electronic integrated circuits, PICs can significantly reduce the system cost, size, weight, and operation power (CSWaP). Recently, the PIC technology has transformed many optical technologies which traditionally rely on tabletop systems and bulky components, such as optical interconnects, nonlinear optics, and quantum photonics, into a chip-scale platform. This device and system miniaturization has successfully led to a wide range of practical applications in computing, sensing, spectroscopy, and communication. However, the traditional passive PIC platform …