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Articles 1 - 30 of 50
Full-Text Articles in Physical Sciences and Mathematics
Stochastic And Copula Models For Credit Derivatives, Chao Meng
Stochastic And Copula Models For Credit Derivatives, Chao Meng
LSU Doctoral Dissertations
We prove results relating to the exit time of a stochastic process from a region in N-dimensional space. We compute certain stochastic integrals involving the exit time. Taking a Gaussian copula model for the hitting time behavior, we prove several results on the sensitivity of quantities connected with the hitting times to parameters of the model, as well as the large-N behavior. We discuss the relationship of these results to certain credit derivative instruments. Relevant simulations are presented.
Towards An Extended Microscopic Theory For Upper-Fp-Shell Nuclei, Kalin Drumev
Towards An Extended Microscopic Theory For Upper-Fp-Shell Nuclei, Kalin Drumev
LSU Doctoral Dissertations
An extended SU(3) shell model that for the first time explicitly includes particles from the unique-parity levels in nuclei is introduced. Its relevance is established through calculations performed with realistic interactions for a group of upper fp-shell isotopes where valence nucleons beyond the N=28=Z core occupy levels of the normal-parity upper $fp$-shell ($f_{5/2},p_{3/2},p_{1/2}$) and the unique-parity $g_{9/2}$ intruder configuration. Specifically, the outcome suggests that the pseudo-SU(3) symmetry is quite good throughout the region and that only part of the configurations are relevant for the structure of the low-lying states. The levels of the upper $fp$-shell are handled within the framework …
Bioanalytical Methods For Studies Of Homocysteine And Novel Cardiovascular Disease Indicators, Arther T. Gates
Bioanalytical Methods For Studies Of Homocysteine And Novel Cardiovascular Disease Indicators, Arther T. Gates
LSU Doctoral Dissertations
This dissertation explores the development of analytical methods for studies of CVD biomarkers and related biomolecular indicators. Initially, spectroscopic studies were conducted to investigate the chemical reactivity of homocysteine (Hcy), an independent CVD risk factor and serological biomarker. Consequently, we proposed an alternate theory for in vivo Hcy clearance based on spontaneous pyridoxal tetrahydrothiazine (PT) formation from Hcy and pyridoxal. The validity of PT-assisted Hcy clearance was further evaluated by use of capillary electrophoretic methods, which allowed rapid monitoring of protein oligomerization in PT-protein reaction mixtures. The results of these studies suggest that PT formation is a plausible mechanism for …
Exploration Of New Ternary Gallides And Investigation Of Their Structure-Property Relationships, Jung Young Cho
Exploration Of New Ternary Gallides And Investigation Of Their Structure-Property Relationships, Jung Young Cho
LSU Doctoral Dissertations
This dissertation focuses on the investigation of new ternary intermetallic gallides, which may exhibit exotic physical properties such as heavy-fermion behavior, large magnetoresistance, and even superconductivity. In particular, the Ln-Cu-Ga (Ln = lanthanides) system has been systematically investigated by changing a reaction ratio and/or using a different temperature profile to optimize desired phases. Single crystals of Ln2MGa12 (Ln = La, Ce; M = Ni, Cu) have been synthesized using Ga flux and compared to their Pd analogues. Interestingly, Ce2MGa12 (M = Ni, Cu) show enhanced Sommerfeld coefficient of ¡Ö 191 mJmol-1K-2 and ¡Ö 69 mJmol-1K-2 for Ni and Cu compounds, …
Syntheses Of Trimethylamine- And Phosphonate- Substituted Carboranylporphyrins For Application In Boron Neutron Cancer Therapy, Michael William Easson
Syntheses Of Trimethylamine- And Phosphonate- Substituted Carboranylporphyrins For Application In Boron Neutron Cancer Therapy, Michael William Easson
LSU Doctoral Dissertations
Chapter 1 contains an introduction to porphyrins and carboranylporphyrins, including their physical properties, history, methods of synthesis, medicinal applications, and an overview of recently published compounds. Chapter 2 contains the total synthesis of a series of trimethylamine- and phosphonate-substituted carboranylporphyrins for application in boron neutron capture therapy (BNCT), including characterization by proton nuclear magnetic resonance spectroscopy, matrix-assisted time-of-flight mass spectroscopy, high resolution mass spectroscopy, UV-Vis spectrophotometry, X-ray crystallography, and melting point apparatus. Chapter 3 contains synthetic methods which were investigated as alternate routes to porphyrin synthesis and functionalization. Chapter 4 presents the in vitro biological evaluation of trimethylamine- and phosphonate-substituted …
Identification Of Quantitative Trait Loci Influencing Early Height Growth In Longleaf Pine (Pinus Palustris Mill), Lisha Wu
LSU Doctoral Dissertations
The delay in early height growth (EHG) has been a limiting factor for artificial regeneration of longleaf pine (Pinus palustris Mill.). Simple Sequence Repeat (SSR) markers have been used to map the genome and quantitative trait loci controlling the EHG in a backcross family (longleaf pine x slash pine) x longleaf pine. A total of 228 locus specific SSR markers were screened against 6 longleaf pine recurrent parents and a sample of 7 longlef x slash pine hybrid parents. In total, 135 polymorphic markers were identified. Based on the genetic variance in EHG, available sample size, and the number of …
Elucidating Marine Pore Water Exchange And Fresh Aquifer Sources In Estimates Of Submarine Groundwater Discharge To A Coastal Lagoon, Christopher Gerald Smith
Elucidating Marine Pore Water Exchange And Fresh Aquifer Sources In Estimates Of Submarine Groundwater Discharge To A Coastal Lagoon, Christopher Gerald Smith
LSU Doctoral Dissertations
Dynamic balances between fresh groundwater, saline groundwater, and surface water control the physics and chemistry of subterranean estuaries. Investigations were performed in a subterranean estuary on physical processes contributing to fresh groundwater and saline water mixing, vertical and lateral positioning of this mixing zone, and how this mixing affects spatial and temporal distributions of 234,238U, 226Ra, and 222Rn. The subterranean estuary is located in an unconfined aquifer beneath Indian River Lagoon, Florida, USA, where I could examine redox responses to altered flow regimes. Continuous groundwater and surface water level measurements suggest a strong hydrologic connection between this …
Generally Covariant Quantum Information, Stephan Jay Olson
Generally Covariant Quantum Information, Stephan Jay Olson
LSU Doctoral Dissertations
The formalism of covariant quantum theory, introduced by Reisenberger and Rovelli, casts the description of quantum states and evolution into a framework compatible with the principles of general relativity. The leap to this covariant formalism, however, outstripped the standard interpretation used to connect quantum theory to experimental predictions, leaving the predictions of the theory ambiguous. In particular, the absence of a pre-defined time variable or background causal structure resulted in an ``order of projections" ambiguity, in which the usual rule for multiple-measurement probabilities (obtained by time-ordered projections) is not defined. Equally troublesome, the probability postulate of Reisenberger and Rovelli fails …
Revolutionizing Genomic Analyses: Mutation Analyses Using Novel Enzyme-Based Assays With Laser-Induced Fluorescence And Polymeric Microfluidic Devices As Electrophoretic Platforms, Rondedrick Deshaun Sinville
Revolutionizing Genomic Analyses: Mutation Analyses Using Novel Enzyme-Based Assays With Laser-Induced Fluorescence And Polymeric Microfluidic Devices As Electrophoretic Platforms, Rondedrick Deshaun Sinville
LSU Doctoral Dissertations
Polymer-based microelectrophoresis was investigated to analyze known (mutation detection) and unknown (mutation scanning) low-abundant mutations in genomic DNA with high diagnostic value for colorectal cancers. For our mutation detection assays, point mutations in the K-ras oncogene were identified using the ligase detection reaction (LDR). For the mutation scanning assay, which searches for sporadic mutations, an EndoV-LDR assay was utilized with mutations in the p53 tumor suppressor gene used as a model. A poly(methylmethacrylate), PMMA, microchip filled with a 4% linear polyacrylamide (LPA) gel was used to electrophoretically sort products formed from LDRs, which produced oligonucleotides <65 bp in length. Using microchip electrophoresis with the LPA, a 44 bp ligation product was resolved from a 100-fold molar excess of unligated primers (25 bp) in approximately 120 s, which was ~17 times faster than conventional capillary gel electrophoresis. In order to simplify the electrophoretic process and further reduce development time, the LDR products were sorted in the absence of the sieving gel using free solution conjugate electrophoresis (FSCE). FSCE incorporated polyamide “drag-tags” onto LDR primers, which provided DNA fragment mobilities in free solution that were dependent upon their size. LDR/drag-tagged (LDR-dt) products could be formed in a multiplexed format for mutant-to-wild-type ratios as low as 1 to 100 with single base resolution. Separations were conducted using capillary array electrophoresis (CAE) and PMMA microchips filled with only a TRIS buffer. Analysis times for the LDR-dt products were less than 11 min using CAE and ~85 s for PMMA microchips with high reproducible migration times within and between microchips. PMMA-based microchips were also evaluated for the identification of sporadic mutations using an endonuclease V – LDR (Endo V/LDR) technique. Endo V cleaves heteroduplexed DNA one base 3’ of single-base mismatched sites as well as nicking DNA at some matched sites as LDR reseals miscleaved sites to reduce false positive signals. Results suggested that Endo V/LDR products from p53 mutations could be successfully separated and detected using a PMMA microfluidic chip filled with a sparsely cross-linked replaceable polyacrylamide gel in less than 6 min, which was approximately 10-fold shorter compared to CAE.
Retro Models Of The Cisplatin-Dna Cross-Link With Carrier Ligands Having Sp2 N-Donor Triazine Rings, Vidhi Maheshwari
Retro Models Of The Cisplatin-Dna Cross-Link With Carrier Ligands Having Sp2 N-Donor Triazine Rings, Vidhi Maheshwari
LSU Doctoral Dissertations
Rapid rotation of guanine base derivatives about Pt–N7 bonds results in fluxional behavior of models of the key DNA intrastrand G–G cross-link leading to anticancer activity of Pt(II) drugs (G = deoxyguanosine). This behavior impedes the characterization of LPtG2 models (L = one bidentate or two cis-unidentate carrier ligands; G = guanine derivative). The objective of this study is to understand the types of conformers formed as L is systematically varied. This work, relevant to Pt(II) anticancer drugs, has evolved from published studies with sp3 N-ligands (e.g., 2,2'-bipiperidine), to C2 symmetrical or unsymmetrical sp2 N-ligands having pyridine and/or triazine rings. …
A Study Of Rheological And Thermodynamic Properties Of Polymer-Clay Gels And Multilayered Films, Eduard Adrian Stefanescu
A Study Of Rheological And Thermodynamic Properties Of Polymer-Clay Gels And Multilayered Films, Eduard Adrian Stefanescu
LSU Doctoral Dissertations
The overall objective of the research presented here is to understand the nanoscopic and microscopic structures that exist in dispersions of laponite and montmorillonite in poly(ethylene oxide), (PEO) and to correlate their shear responses with the final structure and properties of multilayered nanocomposite films prepared from these dispersions. These structures were examined as a function of polymer molecular weight, polymer and clay concentrations, and type of clay used to prepare the nanocomposites. A sequence of shear and elongational rheological measurements is used to provide a more complete physical picture on the structure of polymer-clay hydrogels, while a combination of techniques …
The Synthesis Of Water Soluble N-Acyl Chitosan Derivatives For Characterization As Antibacterial Agents, Lakia Monique Champagne
The Synthesis Of Water Soluble N-Acyl Chitosan Derivatives For Characterization As Antibacterial Agents, Lakia Monique Champagne
LSU Doctoral Dissertations
Currently, natural polysaccharides are being utilized increasingly in the markets because they exhibit biodegradability, biocompatibility, versatility, and are found abundant in nature. The diversity of natural polysaccharides provides the chemist with a broad spectrum of raw materials that can be used in many biological applications. Chitosan is a natural polysaccharide that possesses excellent biological properties. It has been recognized for its antibacterial activity, in that it is destructive towards the bacterium Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The antibacterial property of chitosan can be enhanced by changing the hydrophobic/hydrophilic nature of the polysaccharide backbone. This research entails …
Dactyls Reveal Evolutionary Patterns In Decapod Crustaceans, Jeffrey Guy Agnew
Dactyls Reveal Evolutionary Patterns In Decapod Crustaceans, Jeffrey Guy Agnew
LSU Doctoral Dissertations
Because of their high preservation potential and uses in foraging and defense, decapod crustacean dactyls (movable fingers of claws) are potentially excellent test subjects for an ongoing debate concerning the relative importance of top-down (predators) and bottom-up (prey) controls on morphologic diversification and evolution. The utility of dactyls for inferring evolutionary patterns were evaluated using living and subfossil xanthoid crabs sampled from the southeast U.S. Atlantic and Gulf of Mexico coasts, and were used to: (1) distinguish the roles of selection and constraint on dactyl morphology through allometric and shape comparisons in the context of the crab’s phylogenetic relationships and …
Limit On The Muon Neutrino Magnetic Moment And A Measurement Of The Ccpip To Ccqe Cross Section Ratio, Serge Arisitde Ouedraogo
Limit On The Muon Neutrino Magnetic Moment And A Measurement Of The Ccpip To Ccqe Cross Section Ratio, Serge Arisitde Ouedraogo
LSU Doctoral Dissertations
A search for the muon neutrino magnetic moment was conducted using the Mini- BooNE low energy neutrino data. The analysis was performed by analyzing the elastic scattering interactions of muon neutrinos on electrons. The analysis looked for an excess of elastic scattering events above the Standard Model prediction from which a limit on the neutrino magnetic could be set. In this thesis, we report an excess of 15.3}6.6(stat)}4.1(syst) elastic scattering events above the expected background. At 90% C.L., we derived a limit on the muon neutrino magnetic moment of 12.7~ 10−10ƒÊB. The other analysis reported in this thesis is a …
Differential Geometry In Cartesian Closed Categories Of Smooth Spaces, Martin Laubinger
Differential Geometry In Cartesian Closed Categories Of Smooth Spaces, Martin Laubinger
LSU Doctoral Dissertations
The main categories of study in this thesis are the categories of diffeological and Fr\"olicher spaces. They form concrete cartesian closed categories. In Chapter 1 we provide relevant background from category theory and differentiation theory in locally convex spaces. In Chapter 2 we define a class of categories whose objects are sets with a structure determined by functions into the set. Fr\"olicher's $M$-spaces, Chen's differentiable spaces and Souriau's diffeological spaces fall into this class of categories. We prove cartesian closedness of the two main categories, and show that they have all limits and colimits. We exhibit an adjunction between the …
Solid-Phase Synthesis Of Asymmetrically Substituted Phthalocyanines, Sultan Sibel Erdem
Solid-Phase Synthesis Of Asymmetrically Substituted Phthalocyanines, Sultan Sibel Erdem
LSU Doctoral Dissertations
Phthalocyanines (Pcs) are excellent candidates for use as fluorophores for near-infrared (near-IR) fluorescent tagging of biomolecules and as photodynamic therapy (PDT) agents. Synthesis of Pcs with asymmetrical substitution on the periphery is often difficult due to the problems during the purification of the Pc mixtures obtained. The objective of this project is to design and synthesize chemically robust near-IR fluorophores for bioanalytical applications and to develop new synthetic methods for rapid synthesis of the target compounds. A novel synthetic route was developed utilizing a hydrophilic, polyethylene glycol-based (PEG) support with different types of linkers. The Pcs were functionalized with either …
Searching For Gravitational Waves From Binary Systems In Non-Stationary Data, Chad Hanna
Searching For Gravitational Waves From Binary Systems In Non-Stationary Data, Chad Hanna
LSU Doctoral Dissertations
The gravitational wave detectors at the LIGO Observatories have achieved record sensitivity to gravitational-waves produced by astrophysical systems. The LIGO Scientific Collaboration has analyzed data taken in several science runs, searching for different signals. We describe a search for black holes with less than a solar mass in the LIGO data taken from February 22 to March 24, 2005. No gravitational waves were found, and an upper limit was set on the rate of mergers of such binary systems. This search, as well as other searches for binary systems, are affected by non-stationary noise. We describe the sophisticated pipeline that …
Surgery Description Of Colored Knots, Steven Daniel Wallace
Surgery Description Of Colored Knots, Steven Daniel Wallace
LSU Doctoral Dissertations
By a knot, or link, we mean a circle, or a collection of circles, embedded in the three-sphere S3. The study of knots is a very rich subject and plays a key role in the area of low-dimensional topology. In fact, a theorem of W.B.R. Lickorish and A.D. Wallace states that any three-dimensional manifold may be described by Dehn surgery along a link which is the process of removing the link from S3 and then gluing it back in a way that possibly changes the resulting manifold. In this dissertation, we will be interested in the pair (K, ρ) consisting …
Syntheses And Evaluation Of Phthalocyanine Derivatives For Applications In Photodynamic And Boron Neutron Capture Therapies For Cancer, Hairong Li
LSU Doctoral Dissertations
Chapter I introduced the background of phthalocyanines including its physical properties and various synthetic methods of free-base and metallo-phthalocyanines. The background of PDT and BNCT was introduced and the objective of ideal sensitizers was described. Chapter II described the synthesis and characterization of a series of pyridiloxy-substituted zinc phthalocyanines with different length of alkyl groups. Pyridiloxy-substituted silica phthalocyanines bearing different associated axial ligands, were alkylated with methyl or PEG chains. Biological study was performed on these cationic pyridiloxy-substituted zinc phthalocyanines. Chapter III introduced the synthesis and photophysical properties of A3B-type zinc phthalocyanines conjugated with one or two cobalta-carborane cages. They …
A Novel Automated Approach Of Multi-Modality Retinal Image Registration And Fusion, Hua Cao
A Novel Automated Approach Of Multi-Modality Retinal Image Registration And Fusion, Hua Cao
LSU Doctoral Dissertations
Biomedical image registration and fusion are usually scene dependent, and require intensive computational effort. A novel automated approach of feature-based control point detection and area-based registration and fusion of retinal images has been successfully designed and developed. The new algorithm, which is reliable and time-efficient, has an automatic adaptation from frame to frame with few tunable threshold parameters. The reference and the to-be-registered images are from two different modalities, i.e. angiogram grayscale images and fundus color images. The relative study of retinal images enhances the information on the fundus image by superimposing information contained in the angiogram image. Through the …
Rational Approximation Schemes For Solutions Of Abstract Cauchy Problems And Evolution Equations, Patricio Gabriel Jara
Rational Approximation Schemes For Solutions Of Abstract Cauchy Problems And Evolution Equations, Patricio Gabriel Jara
LSU Doctoral Dissertations
In this dissertation we study time and space discretization methods for approximating solutions of abstract Cauchy problems and evolution equations in a Banach space setting. Two extensions of the Hille-Phillips functional calculus are developed. The first result is the Hille-Phillips functional calculus for generators of bi-continuous semigroups, and the second is a C-regularized version of the Hille-Phillips functional calculus for generators of C-regularized semigroups. These results are used in order to study time discretization schemes for abstract Cauchy problems associated with generators of bi-continuous semigroups as well as C-regularized semigoups. Stability, convergence results, and error estimates for rational approximation schemes …
Effect Of Hydrology On The Structure And Function Of Mangrove Ecosystems In The Can Gio Mangrove Biosphere Reserve, Vietnam, Loi Tan Le
LSU Doctoral Dissertations
The influence of hydrology on the mangrove forests of Vietnam has received little scientific attention, even though hydrology is recognized as the primary forcing function in mangrove ecosystems worldwide. The purpose of this dissertation research was to determine the effects of hydrology on specific structural attributes and functional processes within the mangrove forests of Can Gio, a province in southeastern Vietnam. Khe Vinh (KV) and Mui O (MO), two locations within compartment 17 of the Can Gio Mangrove Biosphere Reserve, were chosen as study sites. This research addressed two questions: (1) What are the characteristics of the hydrological regime at …
Trace Forms Of Abelian Extensions Of Number Fields, Karli Smith
Trace Forms Of Abelian Extensions Of Number Fields, Karli Smith
LSU Doctoral Dissertations
This dissertation is concerned with providing a description of certain symmetric bilinear forms, called trace forms, associated with finite normal extensions N/K of an algebraic number field K, with abelian Galois group Gal(N/K). These abelian trace forms are described up to Witt equivalence, that is, they are described as elements in the Witt ring W(K). Complete descriptions are obtained when the base field K has exactly one dyadic prime and either no real embeddings or one real embedding. For these fields K, the set of abelian trace forms is closed under multiplication in the Witt ring W(K).
Laplace Transform Inversion And Time-Discretization Methods For Evolution Equations, Koray Ozer
Laplace Transform Inversion And Time-Discretization Methods For Evolution Equations, Koray Ozer
LSU Doctoral Dissertations
In this dissertation, we introduce Post-Widder-type inversion methods for the Laplace transform based on A-stable rational approximations of the exponential function. Since the results hold for Banach-space-valued functions, they yield efficient time-discretization methods for evolution equations of convolution type; e.g., linear first and higher order abstract Cauchy problems, inhomogeneous Cauchy problems, delay equations, Volterra and integro-differential equations, and problems that can be re-written as an abstract Cauchy problem on an appropriate state space.
Development Of New Stimuli-Responsive Vesicles Using A Novel Surfactant, Yuming Yang
Development Of New Stimuli-Responsive Vesicles Using A Novel Surfactant, Yuming Yang
LSU Doctoral Dissertations
Many amphiphilic molecules (surfactants) possess the ability to aggregate in aqueous solution to form thermodynamically stable aggregates that have potential for use as molecule containers and delivery systems in analytical or pharmaceutical applications. However, it is difficult to release the encapsulated molecules from these aggregates under a controllable manner, and this problem has dramatically limited the application of these aggregated systems. This study addresses this problem through fundamental structure modification by development of a novel redox stimuli-responsive amphiphile capable of forming vesicle aggregates. Aggregate structure can be adjusted through redox stimulation. The release of agents from the core of the …
Fast Marching Methods - Parallel Implementation And Analysis, Maria Cristina Tugurlan
Fast Marching Methods - Parallel Implementation And Analysis, Maria Cristina Tugurlan
LSU Doctoral Dissertations
Fast Marching represents a very efficient technique for solving front propagation problems, which can be formulated as partial differential equations with Dirichlet boundary conditions, called Eikonal equation: $F(x)|\nabla T(x)|=1$, for $x \in \Omega$ and $T(x)=0$ for $x \in \Gamma$, where $\Omega$ is a domain in $\mathbb{R}^n$, $\Gamma$ is the initial position of a curve evolving with normal velocity F>0. Fast Marching Methods are a necessary step in Level Set Methods, which are widely used today in scientific computing. The classical Fast Marching Methods, based on finite differences, are typically sequential. Parallelizing Fast Marching Methods is a step forward for …
Incorporation Of Cα,Α-Disubstituted Amino Acids Into Model Peptide Systems: Conformational Analysis And Possible Applications As Therapeutic Agents, Marcus A. Etienne
Incorporation Of Cα,Α-Disubstituted Amino Acids Into Model Peptide Systems: Conformational Analysis And Possible Applications As Therapeutic Agents, Marcus A. Etienne
LSU Doctoral Dissertations
A diverse set of human diseases is associated with the misfolding of proteins into insoluble fibrillar structures that have predominantly β-sheet secondary structure. Thus it is imperative to elucidate the structural elements that contribute to β-sheet formation and stability. Peptides that autonomously form β-sheets are ideal models to study principles of protein folding and design. Gellman and coworkers first introduced an automonously folded β-hairpin (H-Arg-Tyr-Val-Glu-Val-Yyy-Xxx-Orn-Lys-Ile-Leu-Gln-NH2) that remained monomeric up to ~1 mM. Circular dichroism (CD) and nuclear magnetic resonance (NMR) analyses revealed that incorporation of non-stereogenic Aib-Xxx dipeptidyl sequences into i+1 and i+2 positions of a model peptide nucleates a …
Landscape Analysis Of Vegetation Change In Coastal Louisiana Following Hurricanes Katrina And Rita, Gregory Dean Steyer
Landscape Analysis Of Vegetation Change In Coastal Louisiana Following Hurricanes Katrina And Rita, Gregory Dean Steyer
LSU Doctoral Dissertations
Investigations of hurricane disturbances on coastal vegetated communities are common, but relatively few are comprehensive across broad geographic regions. The 2005 hurricanes, Katrina and Rita, exposed Louisiana coastal landscapes to physical modifications and extensive and prolonged flooding, resulting in measurable physicochemical changes. This research used remote sensing and field investigations to regionally assess (1) porewater salinity and sulfide impacts to and recovery of coastal Louisiana vegetation communities, and (2) the importance of mineral sediment deposition on accretionary processes. Hurricane effects were most direct and prominent in eastern Louisiana from Katrina and western Louisiana from Rita, compared to central Louisiana exposed …
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry For The Analysis Of Collected Bioaerosols, Alton John Dugas
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry For The Analysis Of Collected Bioaerosols, Alton John Dugas
LSU Doctoral Dissertations
The goal of this dissertation was to demonstrate collection, detection and identification of microorganisms from bioaerosols using offline matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for the analysis of proteins. MALDI-MS intact bacteria techniques were adapted for use with an orthogonal MALDI quadrupole-time-of-flight mass spectrometer. Results indicate the instrument is capable of analyzing intact whole-cells. The first phase was to evaluate three bioaerosol samplers, an Andersen N6 single-stage impactor (AI), a cyclone impactor, and a vacuum filter system. The samplers collected test bioaerosols using a constructed bioaerosol exposure chamber (BEC). The BEC allowed all three samplers to operate in parallel. Each …
Nonperturbative Dynamics Of Strong Interactions From Gauge/Gravity Duality, Hovhannes Roman Grigoryan
Nonperturbative Dynamics Of Strong Interactions From Gauge/Gravity Duality, Hovhannes Roman Grigoryan
LSU Doctoral Dissertations
This thesis studies important dynamical observables of strong interactions such as form factors. It is known that Quantum Chromodynamics (QCD) is a theory which describes strong interactions. For large energies, one can apply perturbative techniques to solve some of the QCD problems. However, for low energies QCD enters into the nonperturbative regime, where different analytical or numerical tools have to be applied to solve problems of strong interactions. The holographic dual model of QCD is such an analytical tool that allows one to solve some nonperturbative QCD problems by translating them into a dual five-dimensional theory defined on some warped …