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Full-Text Articles in Physical Sciences and Mathematics

Investigation Into The Dirhodium-Catalyzed Hydroformylation Of 1-Alkenes And Preparation Of A Novel Tetraphosphine Ligand, Alexandre R. Monteil Jan 2006

Investigation Into The Dirhodium-Catalyzed Hydroformylation Of 1-Alkenes And Preparation Of A Novel Tetraphosphine Ligand, Alexandre R. Monteil

LSU Doctoral Dissertations

The reaction of the tetraphosphine ligand rac-et,ph-P4 (et,ph-P4 = PEt2CH2CH2(Ph)PCH2P(Ph)CH2CH2PEt2) with 2 equiv. of [Rh(nbd)2]+ (nbd = norbornadiene) generates [rac-Rh2(nbd)2(et,ph-P4)]2+, which is the precursor to a highly active and regioselective hydroformylation catalyst system. The “key” catalyst species generated under H2/CO pressure has been proposed to be the dihydrido complex [rac-Rh2H2(ì-CO)2(et,ph-P4)]2+, and represents one of the most dramatic example of homobimetallic …


Effective Inter-Organizational Information And Communication Technology Adoption In Business-To-Business Customer Interface, Sanna Maria Kallioranta Jan 2006

Effective Inter-Organizational Information And Communication Technology Adoption In Business-To-Business Customer Interface, Sanna Maria Kallioranta

LSU Doctoral Dissertations

Past research has found that 80-90 percent of IT investments do not meet corporate performance objectives, primarily due to non-technical reasons such as human and organizational aspects. When Inter-organizational Information and Communication Technology (IICT) implementation is properly managed IICT can help manage the flow of goods, services, and information between business partners in the supplier-customer dyad, thus reducing transaction costs along the entire value chain. Using the underlying Resource-Based View theoretical foundation, this research approaches effective IICT implementation capability as a holistic organizational capability that extends beyond tangible IT resources. This research investigates business outcomes of IICT adoption in the …


Simulating Protein Evolution Via Thermodynamic Models, Yanlong Xu Jan 2006

Simulating Protein Evolution Via Thermodynamic Models, Yanlong Xu

LSU Doctoral Dissertations

Natural proteins are results of evolution and they need to maintain certain thermodynamic stabilities in order to carry out their biological functions. By simulating protein evolution based on thermodynamic rules, we could reconstruct the evolution trajectory and analyze the evolutionary dynamics of a protein population, and further understand the protein sequence-structure-function relationship. In this study, we have used both a simplified lattice model and a high-resolution atomic model to simulate protein evolution processes. With the lattice model, we have investigated general theoretical questions about how protein structural designability would affect protein evolution, particularly how it would affect protein recombination and …


Influence Of Surface Chemistry On The Aggregation Of Beta Amyloid Peptide, Mariah Joan Wooldridge Mcmasters Jan 2006

Influence Of Surface Chemistry On The Aggregation Of Beta Amyloid Peptide, Mariah Joan Wooldridge Mcmasters

LSU Doctoral Dissertations

Alzheimer's disease is a progressive neurological ailment affecting 4.5 million aging Americans. The disease is characterized by the presence in the brain of self-assembled fibrils consisting of beta amyloid protein (Aβ). Soluble Aβ protein is present in normal human cerebrospinal fluid, but it is unclear what makes the protein aggregate into insoluble plaques. There is evidence that the Aβ fibril assembly is affected by interactions with biological surfaces, such as neuronal membranes. Here, surfaces consisting of self-assembled alkanethiol monolayers with different end groups were used to test the effect of surface chemistry on the structure and morphology of aggregates formed …


Infrared Laser Desorption/Ionization Mass Spectrometry: Fundamental And Applications, Mark Little Jan 2006

Infrared Laser Desorption/Ionization Mass Spectrometry: Fundamental And Applications, Mark Little

LSU Doctoral Dissertations

This dissertation on infrared laser desorption/ionization mass spectrometry encompasses fundamental studies of the desorption/ionization process and direct-from-gel laser desorption/ionization applications. Understanding of the fundamentals behind desorption and ionization can lead to improvements in the technique and to new applications. Experiments aimed at advancing this goal are wavelength studies and two-laser infrared/ultraviolet matrix-assisted laser desorption/ionization experiments. The direct-from-gel laser desorption/ionization application in which infrared laser desorption/ionization of analytes directly ionized after gel electrophoretic separation will also be presented. Protein and peptide standards were used as test analytes and the infrared lasers used were a 10.6 micrometers carbon-dioxide laser and a mid-IR …


Ontology-Based Methodology For Error Detection In Software Design, Allyson M. Hoss Jan 2006

Ontology-Based Methodology For Error Detection In Software Design, Allyson M. Hoss

LSU Doctoral Dissertations

Improving the quality of a software design with the goal of producing a high quality software product continues to grow in importance due to the costs that result from poorly designed software. It is commonly accepted that multiple design views are required in order to clearly specify the required functionality of software. There is universal agreement as to the importance of identifying inconsistencies early in the software design process, but the challenge is how to reconcile the representations of the diverse views to ensure consistency. To address the problem of inconsistencies that occur across multiple design views, this research introduces …


A Computational Framework For The Structural Change Analysis Of 3d Volumes Of Microscopic Specimens, Madhusudhanan Balasubramanian Jan 2006

A Computational Framework For The Structural Change Analysis Of 3d Volumes Of Microscopic Specimens, Madhusudhanan Balasubramanian

LSU Doctoral Dissertations

Glaucoma, commonly observed with an elevation in the intraocular pressure level (IOP), is one of the leading causes of blindness. The lamina cribrosa is a mesh-like structure that provides axonal support for the optic nerves leaving the eye. The changes in the laminar structure under IOP elevations may result in the deaths of retinal ganglion cells, leading to vision degradation and loss. We have developed a comprehensive computational framework that can assist the study of structural changes in microscopic structures such as lamina cribrosa. The optical sectioning property of a confocal microscope facilitates imaging thick microscopic specimen at various depths …


Two-Dimensional And High-Throughput Electrophoretic Separation Of Proteins Using Polymeric Microchips, Hamed Shadpour Jan 2006

Two-Dimensional And High-Throughput Electrophoretic Separation Of Proteins Using Polymeric Microchips, Hamed Shadpour

LSU Doctoral Dissertations

A major task in proteomics is to identify proteins from a biological sample using two-dimensional (2-D) separation prior to mass spectrometry of peptides generated via proteolytic digestion of the proteins. For 2-D separations, microfluidic devices are superior to bench top and capillary-based systems since they potentially provide higher separation efficiencies due to the minimal dead volumes produced during peak transfer between the two separation dimensions. In addition, fast separations can be envisioned because the column lengths are typically shorter in microfluidic platforms without scarifying peak capacity. High-throughput capabilities are extremely desirable for many types of bio-analytical analyses, such as understanding …


Filippov's Operator And Discontinuous Differential Equations, Khalid Abdulaziz Alshammari Jan 2006

Filippov's Operator And Discontinuous Differential Equations, Khalid Abdulaziz Alshammari

LSU Doctoral Dissertations

The thesis is mainly concerned about properties of the so-called Filippov operator that is associated with a differential inclusion x'(t) ε F(x(t)) a.e. t ε [0,T], where F : Rn → Rn is given set-valued map. The operator F produces a new set-valued map F[F], which in effect regularizes F so that F[F] has nicer properties. After presenting its definition, we show that F[F] is always upper-semicontinuous as a map from Rn to the metric space of compact subsets of Rn endowed with the Hausdorff metric. Our main approach is to study the …


Multianalyte Detection Of Breast Cancer By Fabrication Of Hybridmicroarrays On Polymer-Based Microanalytical Devices, Suying Wei Jan 2006

Multianalyte Detection Of Breast Cancer By Fabrication Of Hybridmicroarrays On Polymer-Based Microanalytical Devices, Suying Wei

LSU Doctoral Dissertations

Breast cancer is one of the most common and fatal cancer diseases that affect women worldwide. As is true with most other cancer diseases, early detection of breast cancer is very crucial for proper medical treatment because treatment of advanced breast cancer will be much more difficult and inconsistent. Screening and testing of breast cancer biomarkers, either genetic or proteomic, are among techniques used for diagnosis of breast cancers. Nevertheless, none of the biomarkers is by itself sensitive and selective enough for diagnosis of breast cancer, and thus, multi-analyte assays towards detection of multiple breast cancer biomarkers from different classes …


Fabrication, Characterization And Properties Of Hiercchically Ordered Nanocomposites, Avinash Dundigalla Jan 2006

Fabrication, Characterization And Properties Of Hiercchically Ordered Nanocomposites, Avinash Dundigalla

LSU Doctoral Dissertations

The objectives of this research are to study the structure, morphology and properties of poly(ethylene-oxide) (PEO)-clay nanocomposites using various imaging techniques. Optical Microscopy, Scanning Electron Microscopy, Environmental Scanning Electron Microscopy and Atomic Force Microscopy are used to image structures on all length scales. Complementary scattering experiments are discussed along with preliminary differential scanning calorimetry and Fourier Transform Infrared spectroscopy results. In particular we investigated the multilayered structures of PEO-Laponite and PEO-Montmorillonite multilayered films made from solution. The shear orientation of a polymer-clay network in solution combined with simultaneous solvent evaporation leads to supramolecular multilayer formation in the film. The resulting …


A Community Approach To Identifying Essential Fish Habitat Of Spotted Seatrout, Cynoscion Nebulosus, In Barataria Bay, La, Pamela Sharon Dawn Macrae Jan 2006

A Community Approach To Identifying Essential Fish Habitat Of Spotted Seatrout, Cynoscion Nebulosus, In Barataria Bay, La, Pamela Sharon Dawn Macrae

LSU Doctoral Dissertations

Louisiana wetlands are disappearing at a dramatic rate, providing an impetus for identifying essential fish habitat (EFH) in this region. The distribution, relative abundance, biomass, length and food web dynamics of spotted seatrout, Cynoscion nebulosus, as well as the fish assemblage structure were examined in Barataria Bay, LA, in relation to habitat type and physical/chemical properties of the water. All fish were collected from three sites located along a salinity gradient, each contained the three habitat types of interest: marsh edge, soft bottom and oyster shell, and were sampled monthly from May 2003 to May 2004 with gillnets. Habitat preference …


Effective Bootstrapping Of Peer-To Peer Networks Over Mobile Ad-Hoc Networks, Wei Ding Jan 2006

Effective Bootstrapping Of Peer-To Peer Networks Over Mobile Ad-Hoc Networks, Wei Ding

LSU Doctoral Dissertations

Mobile Ad-hoc Networks (MANETs) and Peer-to-Peer (P2P) networks are vigorous, revolutionary communication technologies in the 21st century. They lead the trend of decentralization. Decentralization will ultimately win clients over client/server model, because it gives ordinary network users more control, and stimulates their active participation. It is a determinant factor in shaping the future of networking. MANETs and P2P networks are very similar in nature. Both are dynamic, distributed. Both use multi-hop broadcast or multicast as major pattern of traffic. Both set up connection by self-organizing and maintain connection by self-healing. Embodying the slogan "networking without networks," both abandoned traditional client/server …


A Neural Network Model For Classification Of Coastal Wetlands Vegetation Structure With Moderate Resolution Imaging Spectro-Radiometer (Modis) Data, Evaristo Joseph Liwa Jan 2006

A Neural Network Model For Classification Of Coastal Wetlands Vegetation Structure With Moderate Resolution Imaging Spectro-Radiometer (Modis) Data, Evaristo Joseph Liwa

LSU Doctoral Dissertations

Mapping coastal marshes is an important component in the management of coastal environments. Classification of marshes using remote sensing data has traditionally been performed by employing either parametric supervised classification algorithms or unsupervised classification algorithms. The implementation of these conversional classification methods is based on the underlying distributions concerning the probability density functions (PDF). Neural networks provide a practical approach to this classification because they are essentially non-parametric data transformations that are not restricted by any underlying assumptions. The major objective of this study was to evaluate the ability of neural networks using Moderate Resolution Imaging Spectro-radiometer (MODIS) data to …


Numerical Techniques For Fresnel Diffraction In Computational Holography, Richard Patrick Muffoletto Jan 2006

Numerical Techniques For Fresnel Diffraction In Computational Holography, Richard Patrick Muffoletto

LSU Doctoral Dissertations

Optical holography can produce very realistic virtual images due to its capability to properly convey the depth cues that we use to interpret three-dimensional objects. Computational holography is the use of digital representations plus computational methods to carry out the holographic operations of construction and reconstruction. The large computational requirements of holographic simulations prohibit present-day existence of real-time holographic displays comparable in size to traditional two-dimensional displays. Fourier-based approaches to calculate the Fresnel diffraction of light provide one of the most efficient algorithms for holographic computations because this permits the use of the fast Fourier transform (FFT). The limitations on …


Characterization Of Beta-Amyloid Peptide Aggregation And Acceleration With Non-Fibrillar Forming Peptide-Based Mediators, Nadia J. Edwin Jan 2006

Characterization Of Beta-Amyloid Peptide Aggregation And Acceleration With Non-Fibrillar Forming Peptide-Based Mediators, Nadia J. Edwin

LSU Doctoral Dissertations

Protein aggregation occurs under many circumstances, from the dynamic assembly of tubulin to form microtubules, the aggregation of actin into filaments, as well as plaque formation by amyloid precipitation. One important requirement in studying the mechanism of amyloid aggregation is the ability to monitor the growth kinetics over a wide range in size scales (10 nm to microns) with time that spans microseconds to seconds. Understanding the mechanisms of the aggregation may then lead to improved design of drugs to help control or suppress the aggregation process. In this dissertation, the physical characterization of the â-amyloid peptide and its interaction …


Nutrient Constraints On Plant Community Production And Organic Matter Accumulation Of Subtropical Floating Marshes, Guerry O., Jr. Holm Jr. Jan 2006

Nutrient Constraints On Plant Community Production And Organic Matter Accumulation Of Subtropical Floating Marshes, Guerry O., Jr. Holm Jr.

LSU Doctoral Dissertations

In the cycle of delta growth and decay, peat-forming wetlands span a time and space continuum. Later in the delta cycle, freshwater floating marshes become increasingly removed from external sediment subsidy and internal nutrient cycling controls plant productivity and organic matter accumulation. An interesting question is whether increased external nutrient loading can affect the basic processes that lead to peat formation—plant production and organic matter decomposition. I conducted several field studies to understand whether belowground organic matter accumulation and decomposition were affected with increased nutrient exposure; in addition, the plant community was monitored over three years. A laboratory soil respiration …


Syntheses And Biological Evaluation Of Water Soluble Carboranylporphyrins For Application In Boron Neutron Capture Therapy, Vijay Gottumukkala Jan 2006

Syntheses And Biological Evaluation Of Water Soluble Carboranylporphyrins For Application In Boron Neutron Capture Therapy, Vijay Gottumukkala

LSU Doctoral Dissertations

The goal of the research presented in this dissertation is to develop novel water soluble carboranylporphyrins that can deliver therapeutic dosage of boron specifically to tumors for application in boron neutron capture therapy. In order to accomplish this goal novel water soluble tetra(nido-carboranyl)porphyrin and the octa(nido-carboranyl)porphyrin with high boron contents are synthesized by the condensation of the carborane substituted benzaldehyde with the pyrrole under acidic conditions. These porphyrins are made water soluble by the deboronation of the closo-carboranes to afford the corresponding amphiphilic nido-carborane cages. The low cytotoxicity, high cellular uptake and intracellular localization of these carboranylporphyrins in tumor cells …


An Inverse Homogenization Design Method For Stress Control In Composites, Michael Stuebner Jan 2006

An Inverse Homogenization Design Method For Stress Control In Composites, Michael Stuebner

LSU Doctoral Dissertations

This thesis addresses the problem of optimal design of microstructure in composite materials. The work involves new developments in homogenization theory and numerical analysis. A computational design method for grading the microstructure in composite materials for the control of local stress in the vicinity of stress concentrations is developed. The method is based upon new rigorous multiscale stress criteria connecting the macroscopic or homogenized stress to local stress fluctuations at the scale of the microstructure. These methods are applied to three different types of design problems. The first treats the problem of optimal distribution of fibers with circular cross section …


Integral Cohomology Of The Siegel Modular Variety Of Degree Two And Level Three, Mustafa Arslan Jan 2006

Integral Cohomology Of The Siegel Modular Variety Of Degree Two And Level Three, Mustafa Arslan

LSU Doctoral Dissertations

In this thesis work Deligne's spectral sequence Ep,qr with integer coefficients for the embedding of the Siegel modular variety of degree two and level three, A2(3) into its Igusa compactification, A2(3)*, is investigated. It is shown that E3 = E and this information is applied to compute the cohomology groups of A2(3) over the integers.


Limit Theorems For Weighted Stochastic Systems Of Interacting Particles, Jie Wu Jan 2006

Limit Theorems For Weighted Stochastic Systems Of Interacting Particles, Jie Wu

LSU Doctoral Dissertations

The goal of this dissertation is to (a) establish the weak convergence of empirical measures formed by a system of stochastic differential equations, and (b) prove a comparison result and compactness of support property for the limit measure. The stochastic system of size n has coefficients that depend on the empirical measure determined by the system. The weights for the empirical measure are determined by a further n-system of stochastic equations. There is a random choice among N types of weights. The existence and uniqueness of solutions of the interacting system, weak convergence of the empirical measures, and the identification …


Belowground Biomass Of Spartina Alterniflora: Seasonal Variability And Response To Nutrients, Faith Armand Darby Jan 2006

Belowground Biomass Of Spartina Alterniflora: Seasonal Variability And Response To Nutrients, Faith Armand Darby

LSU Doctoral Dissertations

Spartina alterniflora is a salt marsh macrophyte found from Canada to the Gulf of Mexico which often provides the dominant plant cover. Although S. alterniflora is well known for its high aboveground productivity, fifty to ninety percent of the total plant production occurs belowground. No previous studies address the seasonal variation of belowground biomass or the response of above-and belowground biomass to nutrients at the southern limits of its U. S. range. The objectives of this study were to: 1) document the seasonal variability of its above- and belowground biomass and test for responses to various combinations of N, P, …


Classifying Quadratic Number Fields Up To Arf Equivalence, Jeonghun Kim Jan 2006

Classifying Quadratic Number Fields Up To Arf Equivalence, Jeonghun Kim

LSU Doctoral Dissertations

Two number fields K and L are said to be Arf equivalent if there exists a bijection T : ­ΩK → Ω­L of places of K and of L such that KP and LTP are locally Arf equivalent for every place P ε ΩK. That is, |K*p/K*2p| = |L*TP/L*2TP|, type[( , )P] = type[( , )TP], and Arf(rP ) = Arf(rTP ) for every place P ε ΩK, where rP is the local …


Synthesis, Characterization And Properties Of Cooper(Ii) Beta-Diketonate Macrocycles, Sylvester Burton Jan 2006

Synthesis, Characterization And Properties Of Cooper(Ii) Beta-Diketonate Macrocycles, Sylvester Burton

LSU Doctoral Dissertations

This dissertation deals with the synthesis and properties of multidentate β-diketone ligands and their transition-metal complexes. (1) We prepared two bis(β-diketones), C1BAH2 and p-XBAH2 (see sketch below), determined their crystal structures, and studied their reactions with copper(II). We envisioned that they would form macrocyclic complexes with 3-6 metal atoms. In both cases, although the initial products are soluble, as expected for the desired molecular products, we were unable to isolate well-behaved molecular solids. In the case of C1BAH2, this may be because the cyclic product requires an unusual combination of conformations of …


High Harmonic Generation By Short Laser Pulses: Time-Frequency Behavior And Applications To Attophysics, Mitsuko Murakami Jan 2006

High Harmonic Generation By Short Laser Pulses: Time-Frequency Behavior And Applications To Attophysics, Mitsuko Murakami

LSU Doctoral Dissertations

High harmonic generation (HHG) is a process in which noble gas atoms excited by an intense laser field at frequency ω1 emit radiation of higher frequencies that are odd integer multiples of ω1. Driven by an infrared laser, high harmonic radiation can span from the optical into the extreme ultraviolet (XUV) frequency range. In this thesis, I study HHG using short laser pulses by solving the time-dependent Schrödinger equation (TDSE). In particular, I will focus on calculating and controlling the time-dependent instantaneous frequency (chirp) of high harmonics. The harmonic chirp is a direct consequence of the atom-field …


Integrating Micro-Scale Separations To Matrix Assisted Laser Desorption And Ioniation Time Of Flight Mass Spectrometry (Maldi-Tof-Ms) For Protein Analysis, Harrison K. Musyimi Jan 2006

Integrating Micro-Scale Separations To Matrix Assisted Laser Desorption And Ioniation Time Of Flight Mass Spectrometry (Maldi-Tof-Ms) For Protein Analysis, Harrison K. Musyimi

LSU Doctoral Dissertations

This dissertation describes the integration of micro-scale separations to matrix assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI TOF MS) for protein analysis. MALDI MS provides unsurpassed accurate mass measurements of intact bio-molecules, for example peptides and proteins, which in turn generate high molecular specificity enabling the identity, function and structure of these molecules to be characterized. However, in order to realize the full potential of MS in proteomic studies, integrated sample processing on automated and high throughput platforms is required to address the complexity, diversity and the dynamic range of proteomic analysis. The work described here contributes towards …


Direct Detection Of Homocysteine And Syntheses Of Lanthanide Complexes As Biosensors, Weihua Wang Jan 2006

Direct Detection Of Homocysteine And Syntheses Of Lanthanide Complexes As Biosensors, Weihua Wang

LSU Doctoral Dissertations

At elevated levels, homocysteine (Hcy) is a risk factor for cardiovascular diseases and Alzheimer’s disease. It’s also implicated in a number of other diseases such as neural tube defects, pregnancy complications, and renal failures. The monitoring of Hcy levels in plasma is of current concern. To date, the biochemical mechanism by which Hcy is involved in disease states is unclear. Herein, we describe highly selective colorimetric methods for the direct determination of Hcy. Inexpensive, commercially available materials are reported. The results show potential application for the detection of Hcy in human blood plasma. Additionally, new HPLC postcolumn detection methods for …


Applications Of Titanium-Mediated Reductive Coupling And Cyclocarbonylation Reactions Toward Natural Product Synthesis, Maria A. Appeaning Jan 2006

Applications Of Titanium-Mediated Reductive Coupling And Cyclocarbonylation Reactions Toward Natural Product Synthesis, Maria A. Appeaning

LSU Doctoral Dissertations

Previous work in our laboratory has demonstrated not only a synthetic value of tandem reductive cyclization - carbonylation reactions in the preparation of complex molecules but also the interesting stereoselectivity observed therein. The first part of this work employs the titanium-mediated cyclocarbonylation of tethered dienals for the synthesis of prostaglandin analogues, in particular PGF and methyl jasmonate. Based on this hetero Pauson-Khand strategy, we have established an efficient racemic route to both the prostaglandin and the methyl jasmonate core skeletons. Moderate to excellent selectivities with regard to the hetero Pauson-Khand reaction were observed in both cases. The second part …


Ab Initio Molecular Dynamics Simulations Of Methylaluminoxane (Mao) Synthesis By Hydrolysis Of Trimethylaluminum, Lacramioara Negureanu Jan 2006

Ab Initio Molecular Dynamics Simulations Of Methylaluminoxane (Mao) Synthesis By Hydrolysis Of Trimethylaluminum, Lacramioara Negureanu

LSU Doctoral Dissertations

MAO is the co-catalyst in the metallocene catalytic systems, which are widely used in single site olefin polymerization due to their high stereoselectivity. To date, the precise structure of MAO, the particular compound or compounds catalytically active in MAO, have eluded researchers. MAO, a white amorphous powder, is not a good sample for a direct spectroscopic characterization, and its NMR spectra are broad and almost featureless. Many structural models have been proposed but none are generally accepted. In the first part of this work the MAO formation mechanism was addressed. Molecular dynamics simulations at MP2 configuration interaction theory level have …


Some Factors Affecting The Interfacial Interaction At Thermomechanical Pulp Fiber And Polypropylene Interphase, Sangyeob Lee Jan 2006

Some Factors Affecting The Interfacial Interaction At Thermomechanical Pulp Fiber And Polypropylene Interphase, Sangyeob Lee

LSU Doctoral Dissertations

This dissertation focused on some selected factors that influence the interfacial interactions at the interphase between wood based materials and thermoplastic surfaces. Several treatments were applied to enhance interfacial properties. In general, interfacial properties were altered by physical and chemical surface modification. Study of the interfacial interactions between wood fiber surfaces as a reinforced material and thermoplastics as a matrix material is important to understand fundamentals of wood fiber-plastic composites (WPC). This study represents fundamental research to define treatment effects on surfaces of wood pulp fibers and polypropylene (PP) film. Two thermosets, ion implantations, and maleic anhydride (MA) grafting were …