Physical Sciences and Mathematics Commons^™

Synthesis And Characterization Of Novel Sf5 Containing Fluoroalkyl Iodides And Derivatives, Julia Anne Renn

Dissertations and Theses

Preparation of four SF5-containing fluoroalkyl iodides and derivatives thereof was accomplished beginning with a simplified synthesis of ICF2CF2I. Characterization of the products followed using a variety of spectroscopic and physical methods. The simplified method for preparing ICF2CF2I from iodine and tetrafluoroethylene (TFE) involved a reaction temperature of approximately 54°C and pressures of less than two atmospheres for the TFE. The synthesized ICF2CF2I was reacted with S2F1o and tetrafluoroethylene to give SF5CF2CF2I. The subsequent synthesis of the SFs containing fluoroalkyl iodides and derivatives were carried out using SFsCF2CF2I as the starting material in a Carius tube reaction vessel. The synthesized SFs …

Effects Of The Cardioprotective Drugs Dexrazoxane And Adr-925 On Doxorubicin Induced Ca2+-Release From The Sarcoplasmic Reticulum, Thomas Andreas Herzinger

Dissertations and Theses

The sarcoplasmic reticulum is the intramuscular organelle responsible for the regulation of cytoplasmic calcium levels in muscle. This thesis investigates the effects of the cardioprotective drug, dexrazoxane, and its metabolite ADR-925 on doxorubicin induced calcium release from skeletal sarcoplasmic reticulum. Doxorubicin is a widely used antineoplastic agent. One of the major side effects of doxorubicin usage is chronic cardiotoxicity. Doxorubicin is a potent activator of the calcium release mechanism from the SR. The interaction between doxorubicin and the calcium release channel has been proposed as the possible underlying mechanism behind cardiotoxicity. A short overview of different hypotheses describing doxorubicin induced …

Effective And Appropriate Use Of Controlled Experimentation In Software Development Research, Mark Alan Johnson

Dissertations and Theses

Although there is a large body of research and publication on software development, only a limited amount of this work includes empirical demonstration of its effectiveness. Yet, it is this empirical understanding which will help move software development from a craft to an engineering discipline. Of the empirical methods for research, controlled experiments are the most commonly thought of in scientific studies, and yet the least used to study software development.

This thesis begins with a brief review of the different empirical methods commonly used to study software development. This review provides a quick introduction to each empirical method, compares …

Design Of A Two-Chamber-No₂-Fluorescence-Cell, Volker Schmid

Dissertations and Theses

Nitrogen oxides control the photochemical production of ozone O₃ in the lower atmosphere and influence the concentration of the hydroxyl radical HO in the troposphere. As an important member of the nitrogen oxide family, NO₂ plays a significant role in serving as the only known source of ozone (through photolysis) in the lower atmosphere and as sink for HO via formation of nitric acid. Therefore, accurate measurements of nitrogen dioxide are essential for the understanding of the processes that determine the distribution of tropospheric ozone and for assessing the impact of human activity on the troposphere.

Although reliable and …

Calibration Of A Ccd Camera And Correction Of Its Images, Armin Rest

Dissertations and Theses

Charge-Coupled-Device (CCD) cameras have opened a new world in astronomy and other related sciences with their high quantum efficiency, stability, linearity, and easy handling. Nevertheless, there is still noise in raw CCD images and even more noise is added through the image calibration process. This makes it essential to know exactly how the calibration process impacts the noise level in the image. The properties and characteristics of the calibration frames were explored. This was done for bias frames, dark frames and flat-field frames at different temperatures and for different exposure times.

At first, it seemed advantageous to scale down a …

Distribution Coefficients Of Ionized And Un-Ionized Halogenated Phenols In An Octanol-Water System And Their Relationship To Molecular Structure, Sven Hensler

Dissertations and Theses

Life supporting biological membranes are barriers to toxic chemicals. One of the factors determining the toxicity of chemical compounds is their distribution between membranes and their an environment. An octanol-water system is frequently used as a model for biological membranes to estimate the toxic potency of environmental pollutants. The distribution of a chemical between the octanol and the water phase is described by the octanol-water partition coefficient K_OW. This study is concerned with the relationship between K_OW and the molecular structure of the toxic chemical.

In the study the following trihalophenols were included: 2,4,6-trifluorophenol (TriFP), 2,4,6-trichlorophenol (TriCP); …

Correlation Of The Upper Ellensburg Formation With The Old Scab Mountain Eruptive Center, East-Central Cascade Range, Washington, Christopher Charles Humphrey

Dissertations and Theses

The Ellensburg Formation, preserved in the Nile basin 50 km northwest of Yakima, Washington, consists of a series of middle to late Miocene epiclastic and pyroclastic rock assemblages rich in porphyritic hornblende-biotite dacite. Geochemical, petrographic, and stratigraphic correlations indicate that Old Scab Mountain, a dacite porphyry intrusion, located at the western margin of the basin (lat. 46°53'30", long. 121°13'00"), is the probable source for much of the upper Ellensburg volcaniclastic material in the basin. The dacite intrusion exposed at Old Scab Mountain was emplaced at depths of 1 to 3 km and underlaid a now eroded volcanic edifice. This volcanic …

Beach Response To Subsidence Following A Cascadia Subduction Zone Earthquake Along The Washington-Oregon Coast, Debra Lee Doyle

Dissertations and Theses

Beach shoreline retreat induced by coseismic subsidence in the Cascadia subduction zone is an important post-earthquake hazard. Sand on a beach acts as a buffer to wave attack, protecting dunes, bluffs and terraces. The loss of sand from a beach could promote critical erosion of the shoreline. This study was initiated in order to estimate the potential amount of post subsidence shoreline retreat on a regional scale in the Central Cascadia Margin. The study area is a 331 km stretch of coastline from Copalis, Washington to Florence, Oregon. Several erosion models were evaluated, and the Bruun model was selected as …

Needed Narrowing As The Computational Strategy Of Evaluable Functions In An Extension Of Goedel, Bobbi J. Barry

Dissertations and Theses

A programming language that combines the best aspects of both the functional and logic paradigms with a complete evaluation strategy has been a goal of a Portland State University project team for the last several years. I present the third in a series of modifications to the compiler of the logic programming language Goedel which reaches this goal. This enhancement of Goedel's compiler translates user-defined functions in the form of rewrite rules into code that performs evaluation of these functions by the strategy of needed narrowing. In addition, Goedel's mechanism that evaluates predicates is supplemented so that needed narrowing is …

Wear Due To The Physical And Petrographic Properties Of Rocks And Their Dynamic Interactions With Mining Equipment, Christian Poppeliers

Dissertations and Theses

Wear to mining equipment reduces operational efficiency. If wear rates can be predicted, appropriate matching of alloys to the mine' s geologic conditions can aid in improving the operational efficiency. This study addresses rock characteristics which lead to wear. Macroscopic rock tools which lead to wear include sharp edges and comers on rocks. During a rock/equipment interaction, these rock tools cause high point pressures on the surface of the equipment which leads to ductile cutting and gouging of the surface and subsequent removal of metal. Hard mineral grains, or grain tools, produce abrasion as the grains move across equipment surfaces. …

Abstract Index Interfaces, Muralidharan Janakiraman

Dissertations and Theses

An index in a database system interacts with many of the software modules in the system. For systems supporting a wide range of index structures, interfacing the index code with the rest of the system poses a great problem. The problems are an order of magnitude more for adding new access methods to the system. These problems could be reduced manifold if common interfaces could be specified for different access methods. It would be even better, if these interfaces could be made database-system independent. This thesis addresses the problem of defining generic index interfaces for access methods in database systems. …

Contention-Free Scheduling Of Communication Induced By Array Operations On 2d Meshes, Andreas Bernhard Georg Eberhart

Dissertations and Theses

Whole array operations and array section operations are important features of many data-parallel languages. Efficient implementation of these operations on distributed-memory multicomputers is critical to the scalability and high-performance of data-parallel programs. This thesis presents an approach for analyzing communication patterns induced by array operations and for using run-time information to schedule the message flow. The distributed, dynamic scheduling algorithms guarantee link-contention-free data transfer and utilize network resources almost optimally. They incur little overhead, which is important in order not to reduce the speedup gained by the parallel execution. The algorithms can be used by compilers for the generation of …

Fluorinated Polymer Films - Synthesis And Characterization, Anja Ulrike Schnurer

Dissertations and Theses

Three polyfluoroalkyl epoxides, (I OCH2CHCH20CF2CF2S02F, II OCH2CHCH2(CF2)gF and III OCH2CHCH20(CF2)CF(CF3)S02F) were photopolymerized with a cycloaliphatic diepoxide (Cyracure UVR-6110) to form highly crosslinked glassy films. Depth-dependent surface analysis with XPS show that these films are highly enriched with sulfonyl fluoride groups in the outer molecular surface. Film compositions of 17 % wt and more of the fluorinated I and III show surface characteristics of a film composed of 100 % wt of the polymerized sulfonyl fluoride epoxide monomer (at depths for 50 A for each sample). Even films that are prepared with only 1 % wt or less (compound III) of …

Distribution Of Ionized And Neutral Halogenated Phenols In An Octanol-Water Membrane Model System, Robert Word

Dissertations and Theses

The accumulation of xenobiotics, such as halogenated phenols, in soils, sediments, and living organisms is primarily a partitioning process between an aquatic and organic phase. It is traditional to use a bulk octanol-water system to model the partitioning of a compound between complex biological lipid membranes and aqueous media. The octanol-water partition coefficient K_OW successfully approximates the lipid membrane-water partition coefficient K_LipW of neutral compounds. However, the ionized species of substituted phenols were shown to have a higher affinity for lipid membranes than predicted from octanol-water results.

Data on the octanol-water partition coefficients of molecular ions is limited. …

Nmr Study Of Neurophysin Dimer Dissociation By Cosolvents, Jian Yao

Dissertations and Theses

Neurophysins (NPs) make up a relatively small, stable, and highly soluble class of proteins. They have physiological roles of storage and stabilizing' of peptide hormones oxytocin and vasopression within the posterior pituitary neurosecretory granules. At the concentration of NP found within the granules, NP would exist as a dimer in the absence or presence of bound peptide. The NP monomer-monomer interface involves B-sheet/ B-sheet contact, which can be modulated by the presence of cosolvent. This remarkable feature of NP makes it a model for Alzheimer's disease. One of the characteristics of Alzheimer's disease is the presence of plaques of B-amyloid …

The Use Of Hydrochemistry To Identify Potential Processes Operating In The Saddle Mountains Basalt Aquifer And The Use Of The Nitrate-Nitrogen Isotope To Distinguish Between Potential Sources Of Nitrate To The Shallow Alluvial Aquifer In The Lower Umatilla Basin, Oregon, Margot Truini

Dissertations and Theses

Nitrate concentration in excess of national drinking-water standards (10 mg/l) are present in the shallow alluvial aquifer and Saddle Mountains Basalt (SMB) aquifer in the Lower Umatilla Basin, Oregon. To determine sources responsible for elevated nitrate concentrations in the SMB aquifer mass-balance and reaction-path models (NETPATH and PHREEQE) were used to understand observed geochemical trends. Nitrate-nitrogen isotopes were used to distinguish potential nitrate sources in the shallow alluvial aquifer. NETPATH-validated simple water/rock reactions in the SMB aquifers in Irrigon (dissolving glass, precipitating smectite, dissolving or precipitating calcite, and cation exchange) using constituents (calcium, magnesium, sodium and carbon). Diversity of composition …

Heme Proton Resonance Assignments And Kinetics Study In High-Spin And Mixed-Spin Metmyoglobin Complexes By Chemical Exchange Nmr Spectroscopy, Ying Luo

Dissertations and Theses

NMR studies of paramagnetic hemoproteins have improved significantly our understanding of the structure-function relationship of hemoproteins in general. Up to date most of the studies focus on low-spin ferric systems which are characterized by relatively narrow resonance peaks and concomitant better resolution. However, characterizing in detail the NMR spectra of high-spin ferric hemoproteins is important since there are several hemoproteins, such as peroxidases, catalases, oxygenases, and some ferricytochromes that contain high-spin iron (III) in their biologically active forms. Yet assigning resonances from heme peripheral protons and/or heme pocket residues in high-spin myoglobins is a daunting undertaking. Only a sparse number …

Compiling Evaluable Functions In The GöDel Programming Language, David Shapiro

Dissertations and Theses

We present an extension of the Gödel logic programming language code generator which compiles user-defined functions. These functions may be used as arguments in predicate or goal clauses. They are defined in extended Gödel as rewrite rules. A translation scheme is introduced to convert function definitions into predicate clauses for compilation. This translation scheme and the compilation of functional arguments both employ leftmost-innermost narrowing. As function declarations are indistinguishable from constructor declarations, a function detection method is implemented.

The ultimate goal of this research is the implementation of extended Gödel using needed narrowing. The work presented here is …

The Genetic Algorithm And Maximum Entropy Dice, Laura Suzanne Fellman

Dissertations and Theses

The Brandeis dice problem, originally introduced in 1962 by Jaynes as an illustration of the principle of maximum entropy, was solved using the genetic algorithm, and the resulting solution was compared with that obtained analytically. The effect of varying the genetic algorithm parameters was observed, and the optimum values for population size, mutation rate, and mutation interval were determined for this problem. The optimum genetic algorithm program was then compared to a completely random method of search and optimization. Finally, the genetic algorithm approach was extended to several variations of the original problem for which an analytical approach would be …

A Policy-Independent Secure X Server, Kirk Joseph Bittler

Dissertations and Theses

This thesis demonstrates that a secure X system can be designed and implemented to be independent of a particular security policy. The advantages and costs of a separation of security policy and enforcement are examined by developing a large scale application, the DX windowing system, on a DTOS platform. DTOS is a high assurance operating system that isolates policy decisions in a Security Server. A security conscious process, such as DX, eliminates policy considerations from the code. The process instead consults the Security Server and enforces the decisions that server derives from the policy. The DX architecture is described and …

Mechanisms Of Pentachlorophenol Induced Charge Transport In Lipid Membranes, William Charles Brown

Dissertations and Theses

Pentachlorophenol (PCP) is one of the prominent environmental pollutant that has penetrated into food chain and is present in humans. Health concerns have been raised since daily intake of PCP by the US population is estimated to be 16-19 µg. PCP facilitates dissipation of electrochemical potential gradients of hydrogen ions across energy transducing membranes, which are the energy sources for the conversion of adenosine diphosphate into adenosine triphosphate. Closely linked to these dissipative effects is the development of electrical conductivity in lipid membranes, induced by the presence of PCP. Three modes of PCP - induced membrane electrical conductivity were theoretically …

Captive Environmental Influences On Behavior In Zoo Drills And Mandrills (Mandrillus), A Threatened Genus Of Primate, Erik Terdal

Dissertations and Theses

Drills (Mandrillus leucophaeus) are an endangered species of African monkey (Cercopithecidae), and their sole congener the mandrill (Mandrillus sphinx) is vulnerable to extinction. Both species are threatened in the wild by deforestation and hunting.

Drills have a poor record of captive reproduction. Many individuals appear to have behavioral deficiencies which interfere with reproduction. Thus, the zoo population of drills does not serve as a “hedge” against the species’ total extinction: drills are endangered in captivity as well as in the wild. Mandrills, by contrast, reproduce well in captivity. Information on the behavior of mandrills in captivity may help zoo managers …