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Full-Text Articles in Physical Sciences and Mathematics
Improving Promoter Prediction For The Nnpp2.2 Algorithm: A Case Study Using Escherichia Coli Dna Sequences, Ren Zhang, Alexandra Burden, Yan-Xia Lin
Improving Promoter Prediction For The Nnpp2.2 Algorithm: A Case Study Using Escherichia Coli Dna Sequences, Ren Zhang, Alexandra Burden, Yan-Xia Lin
Associate Professor Yan-Xia Lin
No abstract provided.
The Probability Distribution Of Distance Tss-Tls Is Organism Characteristic And Can Be Used For Promoter Prediction, Yun Dai, Ren Zhang, Yan-Xia Lin
The Probability Distribution Of Distance Tss-Tls Is Organism Characteristic And Can Be Used For Promoter Prediction, Yun Dai, Ren Zhang, Yan-Xia Lin
Associate Professor Yan-Xia Lin
Transcription is a complicated process which involves the interactions of promoter cis-elements with multiple trans-protein factors. The specific interactions rely not only on the specific sequence recognition between the cis- and trans-factors but also on certain spatial arrangement of the factors in a complex. The relative positioning of involved cis-elements provides the framework for such a spatial arrangement. The distance distribution between gene transcription and translation start sites (TSS-TLS) is the subject of the present study to test an assumption that over evolution, the TSS-TLS distance becomes a distinct character for a given organism. Four representative organisms (Escherichia cloi, Saccharomyces …