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- Carbofuran (2)
- Daphnia magna (2)
- Multiple stressors (2)
- Suspended solids (2)
- Abundance (1)
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- Aquatic toxicology (1)
- Binding affinity (1)
- Chemical inventory (1)
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- Ecological risk assessment (1)
- Endocrine disruption (1)
- Estrogen receptor (1)
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- Habitat structure (1)
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- In vitro assays (1)
- Industrial organic chemicals (1)
- Macroinvertebrates (1)
- Publications (1)
- Quantitative structure–activity relationships (1)
- Regulation (1)
- Relative binding affinity (1)
- Risk assessment (1)
- Stones (1)
- Structure–activity relationships (1)
- Synergism (1)
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Articles 1 - 9 of 9
Full-Text Articles in Physical Sciences and Mathematics
Rangeland Rehabilitation: Tal Rimah Case Study, Raed Al-Tabini, H. Soub
Rangeland Rehabilitation: Tal Rimah Case Study, Raed Al-Tabini, H. Soub
Raed Al-Tabini
No abstract provided.
Linear And Nonlinear Effects Of Habitat Structure On Composition And Abundance In The Macroinvertebrate Community Of A Large River, Timothy W. Stewart, Tammy L. Shumaker, Thomas A. Radzio
Linear And Nonlinear Effects Of Habitat Structure On Composition And Abundance In The Macroinvertebrate Community Of A Large River, Timothy W. Stewart, Tammy L. Shumaker, Thomas A. Radzio
Timothy W. Stewart
We used an experiment and regression analyses to quantify effects of spatial variation in habitat structure abundance on a riverine macroinvertebrate community under winter conditions. Concrete slabs (0.21 m2; n 5 24) with different numbers of stones (mean individual stone surface area 5 6.44 cm2) attached to upper faces were placed in the James River and retrieved after 28 d. Macroinvertebrate abundance and taxonomic richness on slabs were significantly positively related to stone abundance. Total macroinvertebrate abundance and abundance of oligochaetes (Nais spp.), Asiatic clams (Corbicula fluminea), caddisflies (Leptoceridae), riffle beetles (Elmidae) and stoneflies (Strophopteryx sp.) were linearly related to …
Seventy Years Of Forest Change In The Northern Great Lakes Region, Usa, Lisa A. Schulte-Moore, Thomas R. Crow, Dave Cleland
Seventy Years Of Forest Change In The Northern Great Lakes Region, Usa, Lisa A. Schulte-Moore, Thomas R. Crow, Dave Cleland
Lisa A. Schulte Moore
The rates and magnitudes of forest change have important social and economic implications. We address facets of change associated with 20th century recovery of the U.S. Lake States (Michigan, Wisconsin, and Minnesota) forests from the Great Cutover, and discuss ecological and socioeconomic implications for future forest resources.
Overview Of Data And Conceptual Approaches For Derivation Of Quantitative Structure-Activity Relationships For Ecotoxicological Effects Of Organic Chemicals, Steven P. Bradbury, Christine L. Russom, Gerald T. Ankley, T. Wayne Schultz, John D. Walker
Overview Of Data And Conceptual Approaches For Derivation Of Quantitative Structure-Activity Relationships For Ecotoxicological Effects Of Organic Chemicals, Steven P. Bradbury, Christine L. Russom, Gerald T. Ankley, T. Wayne Schultz, John D. Walker
Steven P. Bradbury
The use of quantitative structure–activity relationships (QSARs) in assessing potential toxic effects of organic chemicals on aquatic organisms continues to evolve as computational efficiency and toxicological understanding advance. With the everincreasing production of new chemicals, and the need to optimize resources to assess thousands of existing chemicals in commerce, regulatory agencies have turned to QSARs as essential tools to help prioritize tiered risk assessments when empirical data are not available to evaluate toxicological effects. Progress in designing scientifically credible QSARs is intimately associated with the development of empirically derived databases of well-defined and quantified toxicity endpoints, which are based on …
Qsar Prioritization Of Chemical Inventories For Endocrine Disruptor Testing, Steven P. Bradbury, Patricia Schmeider, Ovanes Mekenyan, Gilman Veith
Qsar Prioritization Of Chemical Inventories For Endocrine Disruptor Testing, Steven P. Bradbury, Patricia Schmeider, Ovanes Mekenyan, Gilman Veith
Steven P. Bradbury
Binding affinity between chemicals and the estrogen receptor (ER) serves as an indicator of the potential to cause endocrine disruption through this receptor-mediated endocrine pathway. Estimating ER-binding affinity is, therefore, one strategic approach to reducing the costs of screening chemicals for potential risks of endocrine disruption. While measuring ER binding with in vitro assays may be the first choice in prioritizing chemicals for additional in vitro or in vivo estrogenicity testing, the time and costs associated with screening thousands of chemicals is prohibitive. Recent advances in 3D modeling of the reactivity of flexible structures make in silico methods for estimating …
An Overview Of The Use Of Quantitative Structure-Activity Relationships For Ranking And Prioritzing Large Chemical Inventories For Environmental Risk Assessments, Steven P. Bradbury, Christine L. Russom, Roger L. Breton, John D. Walker
An Overview Of The Use Of Quantitative Structure-Activity Relationships For Ranking And Prioritzing Large Chemical Inventories For Environmental Risk Assessments, Steven P. Bradbury, Christine L. Russom, Roger L. Breton, John D. Walker
Steven P. Bradbury
Ecological risk assessments for chemical stressors are used to establish linkages between likely exposure concentrations and adverse effects to ecological receptors. At times, it is useful to conduct screening risk assessments to assist in prioritizing or ranking chemicals on the basis of potential hazard and exposure assessment parameters. Ranking of large chemical inventories can provide evidence for focusing research and/or cleanup efforts on specific chemicals of concern. Because of financial and time constraints, data gaps exist, and the risk assessor is left with decisions on which models to use to estimate the parameter of concern. In this review, several methods …
Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: Ii. An Evaluation Of Potential Interactive Mechanisms, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer
Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: Ii. An Evaluation Of Potential Interactive Mechanisms, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer
Steven P. Bradbury
It has been demonstrated that simultaneous exposure of Daphnia magna to suspended solids and a carbamate pesticide potentiates the toxic response to the pesticide. The toxicodynamics between these stressors were investigated to determine possible mechanisms of interaction. Three experimental series were conducted with D. magna to determine: the effect of food availability on carbofuran toxicity; the effect of food availability on jointly administered carbofuran and suspended solids; and changes in the magnitude of effects which can occur with suspended solids of different composition. These experiments demonstrated that both carbofuran toxicity and the joint toxicity of carbofuran and suspended solids to …
Quantitative Structure-Activity Relationship Models For Prediction Of Estrogen Receptor Binding Affinity Of Structurally Diverse Chemicals, Steven P. Bradbury, Patricia K. Schmeider, Gerald Ankley, Ovanes Mekenyan, John D. Walker
Quantitative Structure-Activity Relationship Models For Prediction Of Estrogen Receptor Binding Affinity Of Structurally Diverse Chemicals, Steven P. Bradbury, Patricia K. Schmeider, Gerald Ankley, Ovanes Mekenyan, John D. Walker
Steven P. Bradbury
The demonstrated ability of a variety of structurally diverse chemicals to bind to the estrogen receptor has raised the concern that chemicals in the environment may be causing adverse effects through interference with nuclear receptor pathways. Many structure–activity relationship models have been developed to predict chemical binding to the estrogen receptor as an indication of potential estrogenicity. Models based on either two-dimensional or three-dimensional molecular descriptions that have been used to predict potential for binding to the estrogen receptor are the subject of the current review. The utility of such approaches to predict binding potential of diverse chemical structures in …
Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: I. Interactive Effects, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer
Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: I. Interactive Effects, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer
Steven P. Bradbury
This study explored the effects on Daphnia magna from exposure to the pesticide carbofuran in combination with stress from suspended solids exposure. Our objective was to assess whether suspended solids affects the toxicodynamic response of D. magna to carbofuran. A series of laboratory experiments was performed where animals were exposed to carbofuran concentrations ranging from 0 to 160 mg/l in combination with suspended solids concentrations ranging from 0 to 10,000 mg/l. In the absence of suspended solids, effects of carbofuran were dose dependent and resulted in an EC(sub)50 of 92 mg/l. Exposure to suspended solids, up to extreme levels that …