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Full-Text Articles in Physical Sciences and Mathematics

Mining Themes In Clinical Notes To Identify Phenotypes And To Predict Length Of Stay In Patients Admitted With Heart Failure, Ankita Agarwal, Tanvi Banerjee, William Romine, Krishnaprasad Thirunarayan, Lingwei Chen, Mia Cajita May 2023

Mining Themes In Clinical Notes To Identify Phenotypes And To Predict Length Of Stay In Patients Admitted With Heart Failure, Ankita Agarwal, Tanvi Banerjee, William Romine, Krishnaprasad Thirunarayan, Lingwei Chen, Mia Cajita

Computer Science and Engineering Faculty Publications

Heart failure is a syndrome which occurs when the heart is not able to pump blood and oxygen to support other organs in the body. Identifying the underlying themes in the diagnostic codes and procedure reports of patients admitted for heart failure could reveal the clinical phenotypes associated with heart failure and to group patients based on their similar characteristics which could also help in predicting patient outcomes like length of stay. These clinical phenotypes usually have a probabilistic latent structure and hence, as there has been no previous work on identifying phenotypes in clinical notes of heart failure patients …


A Preliminary Study Of The Efficacy Of Using A Wrist-Worn Multiparameter Sensor For The Prediction Of Cognitive Flow States In University-Level Students, Josephine Graft, William Romine, Brooklynn Watts, Noah Schroeder, Tawsik Jawad, Tanvi Banerjee Apr 2023

A Preliminary Study Of The Efficacy Of Using A Wrist-Worn Multiparameter Sensor For The Prediction Of Cognitive Flow States In University-Level Students, Josephine Graft, William Romine, Brooklynn Watts, Noah Schroeder, Tawsik Jawad, Tanvi Banerjee

Computer Science and Engineering Faculty Publications

Engagement is enhanced by the ability to access the state of flow during a task, which is described as a full immersion experience. We report two studies on the efficacy of using physiological data collected from a wearable sensor for the automated prediction of flow. Study 1 took a two-level block design where activities were nested within its participants. A total of five participants were asked to complete 12 tasks that aligned with their interests while wearing the Empatica E4 sensor. This yielded 60 total tasks across the five participants. In a second study representing daily use of the device, …


Predicting Thermoelectric Power Factor Of Bismuth Telluride During Laser Powder Bed Fusion Additive Manufacturing, Ankita Agarwal, Tanvi Banerjee, Joy Gockel, Saniya Leblanc, Joe Walker, John Middendorf Mar 2023

Predicting Thermoelectric Power Factor Of Bismuth Telluride During Laser Powder Bed Fusion Additive Manufacturing, Ankita Agarwal, Tanvi Banerjee, Joy Gockel, Saniya Leblanc, Joe Walker, John Middendorf

Computer Science and Engineering Faculty Publications

An additive manufacturing (AM) process, like laser powder bed fusion, allows for the fabrication of objects by spreading and melting powder in layers until a freeform part shape is created. In order to improve the properties of the material involved in the AM process, it is important to predict the material characterization property as a function of the processing conditions. In thermoelectric materials, the power factor is a measure of how efficiently the material can convert heat to electricity. While earlier works have predicted the material characterization properties of different thermoelectric materials using various techniques, implementation of machine learning models …


Overcoming Uncertainties In Molecular Visualization, Thomas Wischgoll Feb 2023

Overcoming Uncertainties In Molecular Visualization, Thomas Wischgoll

Computer Science and Engineering Faculty Publications

Uncertainties are difficult if not impossible to avoid. Capturing data from the analog world almost always results in some form of uncertainty. The amount of uncertainty depends on the method of measurement and its accuracy. When visualizing data that has some associated uncertainty, it is essential to properly process and convey such uncertainty and especially the amount of uncertainty keeping in mind that additional processing steps can amplify the uncertainty. There are various sources of uncertainty, such as numerical limitations or limitations of the capture device. However, there are other sources of uncertainty. Some of these uncertainties stem from model …


Machine Learning For Angiography-Based Blood Flow Velocity Prediction, Swati Padhee, Mark Johnson, Hang Yi, Tanvi Banerjee, Zifeng Yang Nov 2022

Machine Learning For Angiography-Based Blood Flow Velocity Prediction, Swati Padhee, Mark Johnson, Hang Yi, Tanvi Banerjee, Zifeng Yang

Computer Science and Engineering Faculty Publications

Computational fluid dynamics (CFD) is widely employed to predict hemodynamic characteristics in arterial models, while not friendly to clinical applications due to the complexity of numerical simulations. Alternatively, this work proposed a framework to estimate hemodynamics in vessels based on angiography images using machine learning (ML) algorithms. First, the iodine contrast perfusion in blood was mimicked by a flow of dye diffusing into water in the experimentally validated CFD modeling. The generated projective images from simulations imitated the counterpart of light passing through the flow field as an analogy of X-ray imaging. Thus, the CFD simulation provides both the ground …


Machine Learning For Aiding Blood Flow Velocity Estimation Based On Angiography, Swati Padhee, Mark Johnson, Hang Yi, Tanvi Banerjee, Zifeng Yang Oct 2022

Machine Learning For Aiding Blood Flow Velocity Estimation Based On Angiography, Swati Padhee, Mark Johnson, Hang Yi, Tanvi Banerjee, Zifeng Yang

Computer Science and Engineering Faculty Publications

Computational fluid dynamics (CFD) is widely employed to predict hemodynamic characteristics in arterial models, while not friendly to clinical applications due to the complexity of numerical simulations. Alternatively, this work proposed a framework to estimate hemodynamics in vessels based on angiography images using machine learning (ML) algorithms. First, the iodine contrast perfusion in blood was mimicked by a flow of dye diffusing into water in the experimentally validated CFD modeling. The generated projective images from simulations imitated the counterpart of light passing through the flow field as an analogy of X-ray imaging. Thus, the CFD simulation provides both the ground …


Toward Mental Effort Measurement Using Electrodermal Activity Features, William Romine, Noah Schroeder, Tanvi Banerjee, Josephine Graft Sep 2022

Toward Mental Effort Measurement Using Electrodermal Activity Features, William Romine, Noah Schroeder, Tanvi Banerjee, Josephine Graft

Computer Science and Engineering Faculty Publications

The ability to monitor mental effort during a task using a wearable sensor may improve productivity for both work and study. The use of the electrodermal activity (EDA) signal for tracking mental effort is an emerging area of research. Through analysis of over 92 h of data collected with the Empatica E4 on a single participant across 91 different activities, we report on the efficacy of using EDA features getting at signal intensity, signal dispersion, and peak intensity for prediction of the participant's self-reported mental effort. We implemented the logistic regression algorithm as an interpretable machine learning approach and found …


Leveraging Natural Learning Processing To Uncover Themes In Clinical Notes Of Patients Admitted For Heart Failure, Ankita Agarwal, Krishnaprasad Thirunarayan, William Romine, Amanuel Alambo, Mia Cajita, Tanvi Banerjee Sep 2022

Leveraging Natural Learning Processing To Uncover Themes In Clinical Notes Of Patients Admitted For Heart Failure, Ankita Agarwal, Krishnaprasad Thirunarayan, William Romine, Amanuel Alambo, Mia Cajita, Tanvi Banerjee

Computer Science and Engineering Faculty Publications

Heart failure occurs when the heart is not able to pump blood and oxygen to support other organs in the body as it should. Treatments include medications and sometimes hospitalization. Patients with heart failure can have both cardiovascular as well as non-cardiovascular comorbidities. Clinical notes of patients with heart failure can be analyzed to gain insight into the topics discussed in these notes and the major comorbidities in these patients. In this regard, we apply machine learning techniques, such as topic modeling, to identify the major themes found in the clinical notes specific to the procedures performed on 1,200 patients …


Improving The Factual Accuracy Of Abstractive Clinical Text Summarization Using Multi-Objective Optimization, Amanuel Alambo, Tanvi Banerjee, Krishnaprasad Thirunarayan, Mia Cajita Jul 2022

Improving The Factual Accuracy Of Abstractive Clinical Text Summarization Using Multi-Objective Optimization, Amanuel Alambo, Tanvi Banerjee, Krishnaprasad Thirunarayan, Mia Cajita

Computer Science and Engineering Faculty Publications

While there has been recent progress in abstractive summarization as applied to different domains including news articles, scientific articles, and blog posts, the application of these techniques to clinical text summarization has been limited. This is primarily due to the lack of large-scale training data and the messy/unstructured nature of clinical notes as opposed to other domains where massive training data come in structured or semi -structured form. Further, one of the least explored and critical components of clinical text summarization is factual accuracy of clinical summaries. This is specifically crucial in the healthcare domain, cardiology in particular, where an …


Improving Pain Assessment Using Vital Signs And Pain Medication For Patients With Sickle Cell Disease: Retrospective Study, Swati Padhee, Gary K. Nave Jr, Tanvi Banerjee, Daniel M. Abrams, Nirmish Shah Jun 2022

Improving Pain Assessment Using Vital Signs And Pain Medication For Patients With Sickle Cell Disease: Retrospective Study, Swati Padhee, Gary K. Nave Jr, Tanvi Banerjee, Daniel M. Abrams, Nirmish Shah

Computer Science and Engineering Faculty Publications

Background: Sickle cell disease (SCD) is the most common inherited blood disorder affecting millions of people worldwide. Most patients with SCD experience repeated, unpredictable episodes of severe pain. These pain episodes are the leading cause of emergency department visits among patients with SCD and may last for several weeks. Arguably, the most challenging aspect of treating pain episodes in SCD is assessing and interpreting a patient's pain intensity level. Objective: This study aims to learn deep feature representations of subjective pain trajectories using objective physiological signals collected from electronic health records. Methods: This study used electronic health record data collected …


Entity-Driven Fact-Aware Abstractive Summarization Of Biomedical Literature, Amanuel Alambo, Tanvi Banerjee, Krishnaprasad Thirunarayan, Michael Raymer Mar 2022

Entity-Driven Fact-Aware Abstractive Summarization Of Biomedical Literature, Amanuel Alambo, Tanvi Banerjee, Krishnaprasad Thirunarayan, Michael Raymer

Computer Science and Engineering Faculty Publications

As part of the large number of scientific articles being published every year, the publication rate of biomedical literature has been increasing. Consequently, there has been considerable effort to harness and summarize the massive amount of biomedical research articles. While transformer-based encoder-decoder models in a vanilla source document-to-summary setting have been extensively studied for abstractive summarization in different domains, their major limitations continue to be entity hallucination (a phenomenon where generated summaries constitute entities not related to or present in source article(s)) and factual inconsistency. This problem is exacerbated in a biomedical setting where named entities and their semantics (which …


An Interactive Game With Virtual Reality Immersion To Improve Cultural Sensitivity In Healthcare, Paul J. Hershberger, Yong Pei, Timothy N. Crawford, Sabrina M. Neeley, Thomas Wischgoll, Dixit B. Patel, Miteshkumar M. Vasoya, Angie Castle, Sankalp Mishra, Lahari Surapaneni, Aman A. Pogaku, Aishwarya Bositty, Todd Pavlack Mar 2022

An Interactive Game With Virtual Reality Immersion To Improve Cultural Sensitivity In Healthcare, Paul J. Hershberger, Yong Pei, Timothy N. Crawford, Sabrina M. Neeley, Thomas Wischgoll, Dixit B. Patel, Miteshkumar M. Vasoya, Angie Castle, Sankalp Mishra, Lahari Surapaneni, Aman A. Pogaku, Aishwarya Bositty, Todd Pavlack

Computer Science and Engineering Faculty Publications

Purpose: Biased perceptions of individuals who are not part of one’s in-groups tend to be negative and habitual. Because health care professionals are no less susceptible to biases than are others, the adverse impact of biases on marginalized populations in health care warrants continued attention and amelioration. Method: Two characters, a Syrian refugee with limited English proficiency and a black pregnant woman with a history of opioid use disorder, were developed for an online training simulation that includes an interactive life course experience focused on social determinants of health, and a clinical encounter in a community health center utilizing virtual …


Delaunay Walk For Fast Nearest Neighbor: Accelerating Correspondence Matching For Icp, James D. Anderson, Ryan M. Raettig, Josh Larson, Scott L. Nykl, Clark N. Taylor, Thomas Wischgoll Mar 2022

Delaunay Walk For Fast Nearest Neighbor: Accelerating Correspondence Matching For Icp, James D. Anderson, Ryan M. Raettig, Josh Larson, Scott L. Nykl, Clark N. Taylor, Thomas Wischgoll

Computer Science and Engineering Faculty Publications

Point set registration algorithms such as Iterative Closest Point (ICP) are commonly utilized in time-constrained environments like robotics. Finding the nearest neighbor of a point in a reference 3D point set is a common operation in ICP and frequently consumes at least 90% of the computation time. We introduce a novel approach to performing the distance-based nearest neighbor step based on Delaunay triangulation. This greedy algorithm finds the nearest neighbor of a query point by traversing the edges of the Delaunay triangulation created from a reference 3D point set. Our work integrates the Delaunay traversal into the correspondences search of …


Ufuzzer: Lightweight Detection Of Php-Based Unrestricted File Upload Vulnerabilities Via Static-Fuzzing Co-Analysis, Jin Huang, Junjie Zhang, Jialun Liu, Chuang Li Oct 2021

Ufuzzer: Lightweight Detection Of Php-Based Unrestricted File Upload Vulnerabilities Via Static-Fuzzing Co-Analysis, Jin Huang, Junjie Zhang, Jialun Liu, Chuang Li

Computer Science and Engineering Faculty Publications

Unrestricted file upload vulnerabilities enable attackers to upload malicious scripts to a web server for later execution. We have built a system, namely UFuzzer, to effectively and automatically detect such vulnerabilities in PHP-based server-side web programs. Different from existing detection methods that use either static program analysis or fuzzing, UFuzzer integrates both (i.e., static-fuzzing co-analysis). Specifically, it leverages static program analysis to generate executable code templates that compactly and effectively summarize the vulnerability-relevant semantics of a server-side web application. UFuzzer then “fuzzes” these templates in a local, native PHP runtime environment for vulnerability detection. Compared to static-analysis-based methods, UFuzzer preserves …


Clustering Of Pain Dynamics In Sickle Cell Disease From Sparse, Uneven Samples, Gary K. Nave Jr, Swati Padhee, Amanuel Alambo, Tanvi Banerjee, Nirmish Shah, Daniel M. Abrams Aug 2021

Clustering Of Pain Dynamics In Sickle Cell Disease From Sparse, Uneven Samples, Gary K. Nave Jr, Swati Padhee, Amanuel Alambo, Tanvi Banerjee, Nirmish Shah, Daniel M. Abrams

Computer Science and Engineering Faculty Publications

Irregularly sampled time series data are common in a variety of fields. Many typical methods for drawing insight from data fail in this case. Here we attempt to generalize methods for clustering trajectories to irregularly and sparsely sampled data. We first construct synthetic data sets, then propose and assess four methods of data alignment to allow for application of spectral clustering. We also repeat the same process for real data drawn from medical records of patients with sickle cell disease -- patients whose subjective experiences of pain were tracked for several months via a mobile app. We find that different …


Uncertainty-Aware Visualization In Medical Imaging - A Survey, Christina Gillmann, Dorothee Saur, Thomas Wischgoll, Gerik Scheuermann Jun 2021

Uncertainty-Aware Visualization In Medical Imaging - A Survey, Christina Gillmann, Dorothee Saur, Thomas Wischgoll, Gerik Scheuermann

Computer Science and Engineering Faculty Publications

Medical imaging (image acquisition, image transformation, and image visualization) is a standard tool for clinicians in order to make diagnoses, plan surgeries, or educate students. Each of these steps is affected by uncertainty, which can highly influence the decision-making process of clinicians. Visualization can help in understanding and communicating these uncertainties. In this manuscript, we aim to summarize the current state-of-the-art in uncertainty-aware visualization in medical imaging. Our report is based on the steps involved in medical imaging as well as its applications. Requirements are formulated to examine the considered approaches. In addition, this manuscript shows which approaches can be …


Nomophobia Before And After The Covid-19 Pandemic-Can Social Media Be Used To Understand Mobile Phone Dependency, Vaishnavi Visweswaraiah, Tanvi Banerjee, William Romine, Sarah Fryman Jun 2021

Nomophobia Before And After The Covid-19 Pandemic-Can Social Media Be Used To Understand Mobile Phone Dependency, Vaishnavi Visweswaraiah, Tanvi Banerjee, William Romine, Sarah Fryman

Computer Science and Engineering Faculty Publications

No abstract provided.


Neuro-Symbolic Deductive Reasoning For Cross-Knowledge Graph Entailment, Monireh Ebrahimi, Md Kamruzzaman Sarker, Federico Bianchi, Ning Xie, Aaron Eberhart, Derek Doran, Hyeongsik Kim, Pascal Hitzler Mar 2021

Neuro-Symbolic Deductive Reasoning For Cross-Knowledge Graph Entailment, Monireh Ebrahimi, Md Kamruzzaman Sarker, Federico Bianchi, Ning Xie, Aaron Eberhart, Derek Doran, Hyeongsik Kim, Pascal Hitzler

Computer Science and Engineering Faculty Publications

A significant and recent development in neural-symbolic learning are deep neural networks that can reason over symbolic knowledge graphs (KGs). A particular task of interest is KG entailment, which is to infer the set of all facts that are a logical consequence of current and potential facts of a KG. Initial neural-symbolic systems that can deduce the entailment of a KG have been presented, but they are limited: current systems learn fact relations and entailment patterns specific to a particular KG and hence do not truly generalize, and must be retrained for each KG they are tasked with entailing. We …


Leveraging Natural Language Processing To Mine Issues On Twitter During The Covid-19 Pandemic, Ankita Agarwal, Preetham Salehundam, Swati Padhee, William Romine, Tanvi Wright State University - Main Campus Mar 2021

Leveraging Natural Language Processing To Mine Issues On Twitter During The Covid-19 Pandemic, Ankita Agarwal, Preetham Salehundam, Swati Padhee, William Romine, Tanvi Wright State University - Main Campus

Computer Science and Engineering Faculty Publications

The recent global outbreak of the coronavirus disease (COVID-19) has spread to all corners of the globe. The international travel ban, panic buying, and the need for self-quarantine are among the many other social challenges brought about in this new era. Twitter platforms have been used in various public health studies to identify public opinion about an event at the local and global scale. To understand the public concerns and responses to the pandemic, a system that can leverage machine learning techniques to filter out irrelevant tweets and identify the important topics of discussion on social media platforms like Twitter …


Topic-Centric Unsupervised Multi-Document Summarization Of Scientific And News Articles, Amanuel Alambo, Cori Lohstroh, Erik Madaus, Swati Padhee, Brandy Foster, Tanvi Banerjee, Krishnaprasad Thirunarayan, Michael Raymer Mar 2021

Topic-Centric Unsupervised Multi-Document Summarization Of Scientific And News Articles, Amanuel Alambo, Cori Lohstroh, Erik Madaus, Swati Padhee, Brandy Foster, Tanvi Banerjee, Krishnaprasad Thirunarayan, Michael Raymer

Computer Science and Engineering Faculty Publications

Recent advances in natural language processing have enabled automation of a wide range of tasks, including machine translation, named entity recognition, and sentiment analysis. Automated summarization of documents, or groups of documents, however, has remained elusive, with many efforts limited to extraction of keywords, key phrases, or key sentences. Accurate abstractive summarization has yet to be achieved due to the inherent difficulty of the problem, and limited availability of training data. In this paper, we propose a topic-centric unsupervised multi-document summarization framework to generate extractive and abstractive summaries for groups of scientific articles across 20 Fields of Study (FoS) in …


Can Subjective Pain Be Inferred From Objective Physiological Data? Evidence From Patients With Sickle Cell Disease, Mark J. Panaggio, Daniel M. Abrams, Fan Yang, Tanvi Banerjee, Nirmish R. Shah Mar 2021

Can Subjective Pain Be Inferred From Objective Physiological Data? Evidence From Patients With Sickle Cell Disease, Mark J. Panaggio, Daniel M. Abrams, Fan Yang, Tanvi Banerjee, Nirmish R. Shah

Computer Science and Engineering Faculty Publications

Patients with sickle cell disease (SCD) experience lifelong struggles with both chronic and acute pain, often requiring medical interventMaion. Pain can be managed with medications, but dosages must balance the goal of pain mitigation against the risks of tolerance, addiction and other adverse effects. Setting appropriate dosages requires knowledge of a patient's subjective pain, but collecting pain reports from patients can be difficult for clinicians and disruptive for patients, and is only possible when patients are awake and communicative. Here we investigate methods for estimating SCD patients' pain levels indirectly using vital signs that are routinely collected and documented in …


An Analysis Of C/C++ Datasets For Machine Learning-Assisted Software Vulnerability Detection, Daniel Grahn, Junjie Zhang Jan 2021

An Analysis Of C/C++ Datasets For Machine Learning-Assisted Software Vulnerability Detection, Daniel Grahn, Junjie Zhang

Computer Science and Engineering Faculty Publications

As machine learning-assisted vulnerability detection research matures, it is critical to understand the datasets being used by existing papers. In this paper, we explore 7 C/C++ datasets and evaluate their suitability for machine learning-assisted vulnerability detection. We also present a new dataset, named Wild C, containing over 10.3 million individual opensource C/C++ files – a sufficiently large sample to be reasonably considered representative of typical C/C++ code. To facilitate comparison, we tokenize all of the datasets and perform the analysis at this level. We make three primary contributions. First, while all the datasets differ from our Wild C dataset, some …


Augmented Reality Headset Facilitates Exposure For Surgical Stabilization Of Rib Fractures, T. Sensing, Pratik Parikh, Claire Hardman, Thomas Wischgoll, Sadan Suneesh Menon Jan 2021

Augmented Reality Headset Facilitates Exposure For Surgical Stabilization Of Rib Fractures, T. Sensing, Pratik Parikh, Claire Hardman, Thomas Wischgoll, Sadan Suneesh Menon

Computer Science and Engineering Faculty Publications

Recent advances in augmented reality (AR) technology have made it more accessible, portable, and powerful. AR headsets differentiate themselves from virtual reality in that they allow the wearer an unobstructed view of the “real world” but with an image superimposed upon it. The technology has many potential applications in medicine, including surgical planning, simulation, and medical education. The aim of this project was to provide proof of concept that using an AR headset during surgical stabilization of rib fractures (SSRF) is feasible. We theorized that the use of AR could allow for more precise localization of fractures, allowing for smaller …


Pain Intensity Assessment In Sickle Cell Disease Patients Using Vital Signs During Hospital Visits, Swati Padhee, Amanuel Alambo, Tanvi Banerjee, Arvind Subramaniam, Daniel M. Abrams, Gary K. Nave, Nirmish Shah Jan 2021

Pain Intensity Assessment In Sickle Cell Disease Patients Using Vital Signs During Hospital Visits, Swati Padhee, Amanuel Alambo, Tanvi Banerjee, Arvind Subramaniam, Daniel M. Abrams, Gary K. Nave, Nirmish Shah

Computer Science and Engineering Faculty Publications

Pain in sickle cell disease (SCD) is often associated with increased morbidity, mortality, and high healthcare costs. The standard method for predicting the absence, presence, and intensity of pain has long been self-report. However, medical providers struggle to manage patients based on subjective pain reports correctly and pain medications often lead to further difficulties in patient communication as they may cause sedation and sleepiness. Recent studies have shown that objective physiological measures can predict subjective self-reported pain scores for inpatient visits using machine learning (ML) techniques. In this study, we evaluate the generalizability of ML techniques to data collected from …


Covid-19 And Mental Health/Substance Use Disorders On Reddit: A Longitudinal Study, Amanuel Alambo, Swati Padhee, Tanvi Banerjee, Krishnaprasad Thirunarayan Nov 2020

Covid-19 And Mental Health/Substance Use Disorders On Reddit: A Longitudinal Study, Amanuel Alambo, Swati Padhee, Tanvi Banerjee, Krishnaprasad Thirunarayan

Computer Science and Engineering Faculty Publications

COVID-19 pandemic has adversely and disproportionately impacted people suffering from mental health issues and substance use problems. This has been exacerbated by social isolation during the pandemic and the social stigma associated with mental health and substance use disorders, making people reluctant to share their struggles and seek help. Due to the anonymity and privacy they provide, social media emerged as a convenient medium for people to share their experiences about their day to day struggles. Reddit is a well-recognized social media platform that provides focused and structured forums called subreddits, that users subscribe to and discuss their experiences with …


Multi-Echo Quantitative Susceptibility Mapping For Strategically Acquired Gradient Echo (Stage) Imaging, Sara Gharabaghi, Saifeng Liu, Ying Wang, Yongsheng Chen, Sagar Buch, Mojtaba Jokar, Thomas Wischgoll, Nasser H. Kashou, Chunyan Zhang, Bo Wu, Jingliang Cheng, E. Mark Haacke Oct 2020

Multi-Echo Quantitative Susceptibility Mapping For Strategically Acquired Gradient Echo (Stage) Imaging, Sara Gharabaghi, Saifeng Liu, Ying Wang, Yongsheng Chen, Sagar Buch, Mojtaba Jokar, Thomas Wischgoll, Nasser H. Kashou, Chunyan Zhang, Bo Wu, Jingliang Cheng, E. Mark Haacke

Computer Science and Engineering Faculty Publications

Purpose: To develop a method to reconstruct quantitative susceptibility mapping (QSM) from multi-echo, multi-flip angle data collected using strategically acquired gradient echo (STAGE) imaging. Methods: The proposed QSM reconstruction algorithm, referred to as “structurally constrained Susceptibility Weighted Imaging and Mapping” scSWIM, performs an ℓ1 and ℓ2 regularization-based reconstruction in a single step. The unique contrast of the T1 weighted enhanced (T1WE) image derived from STAGE imaging was used to extract reliable geometry constraints to protect the basal ganglia from over-smoothing. The multi-echo multi-flip angle data were used for improving the contrast-to-noise ratio in QSM through a weighted averaging scheme. The …


Uncertainty-Aware Brain Lesion Visualization, Christina Gillmann, Dorothee Saur, Thomas Wischgoll, Karl T. Hoffman, Hans Hagen, Ross Maciejewski, Gerik Scheuermann Jan 2020

Uncertainty-Aware Brain Lesion Visualization, Christina Gillmann, Dorothee Saur, Thomas Wischgoll, Karl T. Hoffman, Hans Hagen, Ross Maciejewski, Gerik Scheuermann

Computer Science and Engineering Faculty Publications

A brain lesion is an area of tissue that has been damaged through injury or disease. Its analysis is an essential task for medical researchers to understand diseases and find proper treatments. In this context, visualization approaches became an important tool to locate, quantify, and analyze brain lesions. Unfortunately, image uncertainty highly effects the accuracy of the visualization output. These effects are not covered well in existing approaches, leading to miss-interpretation or a lack of trust in the analysis result. In this work, we present an uncertainty-aware visualization pipeline especially designed forbrain lesions. Our method is based on an uncertainty …


Medical Education And Assisted Surgery By Ar, Sadan Suneesh Menon, Thomas Wischgoll, Sharon Farra, Cindra Holland Jan 2020

Medical Education And Assisted Surgery By Ar, Sadan Suneesh Menon, Thomas Wischgoll, Sharon Farra, Cindra Holland

Computer Science and Engineering Faculty Publications

No abstract provided.


Predicting Early Indicators Of Cognitive Decline From Verbal Utterances, Swati Padhee, Anurag Illendula, Megan Sadler, Valerie L. Shalin, Tanvi Banerjee, Krishnaprasad Thirunarayan, William Romine Jan 2020

Predicting Early Indicators Of Cognitive Decline From Verbal Utterances, Swati Padhee, Anurag Illendula, Megan Sadler, Valerie L. Shalin, Tanvi Banerjee, Krishnaprasad Thirunarayan, William Romine

Computer Science and Engineering Faculty Publications

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the earliest clinically detectable stage of incipient dementia, commonly known as mild cognitive impairment (MCI). Currently, these disorders are diagnosed using a manual analysis of neuropsychological examinations. We measure the feasibility of using the linguistic characteristics of verbal utterances elicited during neuropsychological exams of elderly subjects to distinguish between elderly control groups, people with MCI, people diagnosed with possible Alzheimer's disease (AD), and probable AD. We investigated the performance …


Deep Neural Ranking For Crowdsourced Geopolitical Event Forecasting, Giuseppe Nebbione, Derek Doran, Srikanth Nadella, Brandon Minnery May 2019

Deep Neural Ranking For Crowdsourced Geopolitical Event Forecasting, Giuseppe Nebbione, Derek Doran, Srikanth Nadella, Brandon Minnery

Computer Science and Engineering Faculty Publications

There are many examples of “wisdom of the crowd” effects in which the large number of participants imparts confidence in the collective judgment of the crowd. But how do we form an aggregated judgment when the size of the crowd is limited? Whose judgments do we include, and whose do we accord the most weight? This paper considers this problem in the context of geopolitical event forecasting, where volunteer analysts are queried to give their expertise, confidence, and predictions about the outcome of an event. We develop a forecast aggregation model that integrates topical information about a question, meta-data about …