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Animal Experimentation and Research
Loma Linda University Electronic Theses, Dissertations & Projects
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The Role Of T Cells In The Pathogenesis Of Periapical Lesions, John B. Wallstrom
The Role Of T Cells In The Pathogenesis Of Periapical Lesions, John B. Wallstrom
Loma Linda University Electronic Theses, Dissertations & Projects
The pulps of mandibular molars of 15 athymic and 15 conventional rats were surgically exposed and left open to their oral flora. Each group was divided into 3 subgroups of 5 animals each. The rats were sacrificed after their pulps were exposed for 2, 4, or 8 weeks. After fixing, decalcifying, and embedding, the specimens were sectioned and stained with H and E. They were then examined under a microscopic grid and quantified by percentages of surface areas of bone, connective tissue, bone marrow, intrabony spaces, periapical lesions, and numbers of osteoclasts. This was done using a DataVoice computerized data …