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Investigating The Influence Of Prenatal Metals Exposures On Childhood Mitochondrial Biomarkers, Z'Dhanne Williams
Investigating The Influence Of Prenatal Metals Exposures On Childhood Mitochondrial Biomarkers, Z'Dhanne Williams
Molloy Multidisciplinary Undergraduate Research Conference
Note: Z'Dhanne is a current Molloy student and conducted this research while studying at Columbia University - Mailman School of Public Health
Abstract
Background and Purpose: Mitochondrial health plays a vital role in the development of chronic health conditions, including neurodegenerative and cardiovascular diseases. Mitochondria have the unique ability to independently control replication of mitochondrial DNA (mtDNA) depending on conditions of cellular stress, including oxidative stress. Exposure to environmental metals affects a variety of health outcomes via oxidative stress pathways. Our objective was to determine the association between prenatal exposure to metals on two biomarkers of mtDNA in child blood: …