Environmental Public Health Commons^™

Environmental Exposures And Aging., Daniel Chris Gomes

Electronic Theses and Dissertations

In recent years, research into air pollution has shown that exposure to certain components in air pollution, primarily PM2.5 can accelerate biological aging and thereby lead to increased susceptibility to multiple diseases. We hypothesize that prolonged exposure to air pollutants can result in premature aging leading to extensive tissue dysfunction and susceptibility to diseases. To examine this, we exposed mice to PM2.5 for 9, 15, and 21 days, then measured the telomere lengths, cellular senescence, and histone methylation patterns of multiple cell types. We found consistently increased telomere attrition, cellular senescence and advanced age-consistent histone methylation patterns in groups exposed …

Editorial: The Public Health Scholars As The Health Leaders, Al Asyary, Meita Veruswati, Putri Bungsu Machmud, Indri Hapsari Susilowati

Kesmas

No abstract provided.

Spatial Associations Of Liver Disease Rates With Socioeconomic And Health Risk Factors In Georgia, Nguyet Le

Symposium of Student Scholars

According to the CDC Cancer Statistics Report in 2020, Liver and Intrahepatic Bile Duct is the 6th leading cancer in both USA and the State of Georgia ranked by Rates of Cancer Death. Aflatoxin-containing foods, alcohol consumption, smoking, overeating, and other risky behaviors are among the factors linked to liver diseases. They have also been related to the socioeconomic status (SES) of individuals. The behaviors and SES of individuals are affected by the socioeconomic characteristics of the communities where they live. However, the relationships between the rates of liver diseases and community-level socioeconomic factors are not well studied. The objective …

Tobacco, Alcohol And Diet As Mortality Risk Factors: The Secondary Analysis Of The 25-Year Cohort Study, Alina Egorova, Bulat Idrisov, Romany Redman, Stanislav Otstavnov, Sergey Soshnikov

Journal of Health Research

Background: Individual lifestyle risk factors have been linked to increased mortality globally; however, there is limited data on these associations in Russia. A secondary analysis of the Russia Longitudinal Monitoring Survey (RLMS) data was conducted to close this gap.

Methods: The secondary data have been obtained from a nationally-representative annual cohort survey conducted by the Higher School of Economics (HSE). In this original study, for the first time in Russia, we extracted RRs for researched risk factors. Of additional original value, we made a prospective-retrospective cohort based on a representative longitudinal survey and provided the deaths as outcomes for survival …

Self-Reported Consumption Of Bottled Water V. Tap Water In Appalachian And Non-Appalachian Kentucky, Jason W. Marion

Journal of Appalachian Health

Introduction: Quantitative studies on drinking water perceptions in Appalachia are limited. High-profile water infrastructure failures in the U.S. and Eastern Kentucky, coupled with human-made and natural disasters in the Appalachian Region, have likely impacted opinions regarding tap water.

Purpose: To use existing unexplored data to describe baseline tap water v. bottled water consumption in Kentucky.

Methods: Telephone-based cross-sectional data were obtained from the 2013 Kentucky Health Issues Poll (KHIP) directed by the Foundation for a Healthy Kentucky. Among many items in KHIP, self-reported consumption of bottled water over tap water, reasons for bottled water use, and demographic data were obtained. …

Investigation Of Orthohantavirus Genetics In Rodent Reservoirs And Clinical Samples, Samuel M Goodfellow

Biomedical Sciences ETDs

Orthohantaviruses are negative-sense, single stranded RNA viruses with trisegmented genomes that can cause severe disease in humans and are carried by several host reservoirs throughout the world. In the United States, Sin Nombre orthohantavirus (SNV) is the primary cause of hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of ~36% and the highest cases occuring in the southwest region. The primary SNV host reservoir is thought to be the western deer mouse, Peromyscus maniculatus, however it has been shown that other rodents can carry different orthohantaviruses. We designed a pan-orthohantavirus detection tool to survey several small mammal populations throughout New …

Clinical And Environmental Factors Affecting The Survival Outcomes Among Stage 1a Tn0m0 First Primary Non-Small Cell Lung Carcinoma Patients In The United States., Naiya Patel

Electronic Theses and Dissertations

Background: Lung cancer is the second leading cause of death in the United States (U.S.). The most prevalent histological type of lung cancer is Non-Small Cell Lung Cancer (NSCLC), which has an overall five years survival of 5% if left untreated. Therefore, early treatment of NSCLC is vital to improve overall survival (OS) outcomes. Several factors affect survival outcomes, which can be categorized as modifiable or non-modifiable. The difference in timely receipt of guideline-concordant treatment affects the survival outcomes of patients with stage 1A NSCLC. This dissertation explored factors that affect treatment and survival outcomes among stage 1A NSCLC patients …

Editorial, Al Asyary

Kesmas

No abstract provided.

The Influence Of The Covid-19 Pandemic On Physical Growth And Personal Hygiene Of Adolescents, Ruslan Halifu, Ahmad Amiruddin, Wa Ode Nesya J Samrida, Wa Ode Sitti Justin, Selvi Mayang Sari, Sudirman Pabokori

Kesmas

The COVID-19 pandemic has influenced the community's lifestyle, including adolescents’ behavior. One aspect majorly affected was physical growth, which encompasses several areas, including nutritional status and personal hygiene. Maintaining the quality of physical growth is very important, even beyond the pandemic. Therefore, this study aimed to determine the influence of the COVID-19 pandemic on adolescents' nutritional status and personal hygiene. A literature review method was used through a bibliometric and content analysis of publications obtained from databases such as Google Scholar. The articles obtained were classified by publication year, study location, keywords, and journal titles. Based on the literature search, …

Extremely Hot Ambient Temperature And Injury-Related Mortality, Mien T N Nguyen, Man V M Nguyen, Huong V T Le, Hoai Viet Nguyen, Vu Anh Nguyen, Ngoan Tran Le

Kesmas

This pilot study aimed to evaluate the effects of extremely hot ambient temperatures on the total number of fatal injuries. Data were collected from a population-based mortality registry of Thanh Hoa, a province in the North Central region of Vietnam. This study qualified the distributed lag non-linear model and calculated the RR and 95% CI adjusted for long-term trend and absolute humidity. For the entire study population with 3,949 registered deaths due to injuries collected during 2005-2007, after the onset of extremely hot ambient temperatures, an increased risk of death was observed on the 9th day RR (95% CI) = …

Assessment Of Rabies Control Attitudes During The Covid-19 Pandemic Through Partial Least Square-Structural Equation Modeling, Sang Gede Purnama, Ni Wayan Arya Utami, Made Subrata, Putu Erma Pradnyani, Karang Agustina, Ibn Swacita

Kesmas

The COVID-19 pandemic disrupts rabies control activities in the community. A new approach is needed to control rabies during the COVID-19 pandemic through digital health interventions by conducting digital surveillance and education. This study aimed to determine key attitude indicators in controlling rabies during the COVID-19 pandemic. A cross-sectional study on 166 participants in Denpasar City with a total of 31 indicators measuring five variables: perceptions of the benefits of rabies control (6 indicators), perceptions of rabies risk (6 indicators), perceptions of obstacles to rabies control (5 indicators), perceptions of the need for technology (7 indicators), and attitudes toward rabies …

Please Romaine Calm! A Multi-Disciplinary Investigation Of A Cyclospora Outbreak Among Hospital Employees, Jocelyn Love Mph, Amber Erickson Drph, Mph, Hope Dishman Mph, Carla Coley Bs, Rehs

Georgia Public Health Association Annual Meeting and Conference

Background

On July 8, 2022, North Central Health District (NCHD) was notified by a local hospital of a possible Cyclospora outbreak among hospital employees. The hospital noted the employees had eaten at the hospital’s cafeteria, particularly the salad bar. An investigation was conducted to test this hypothesis and determine which salad bar ingredients were the cause of illness.

Methods

An electronic survey was shared with all hospital employees through their email distribution system. Employees were asked to complete the survey regardless of illness or exposure history. Lab- confirmed cases were interviewed using the Cyclosporiasis National Hypothesis Generating Questionnaire. Environmental health …

Environmental And Social Factors Associated With High Chronic Kidney Disease Mortality Rates In Municipalities Of Guatemala: An Ecological Study Of Municipal-Level Mortality Data, Alejandro Cerón

Anthropology: Faculty Scholarship

The purpose of this study was to determine the association between social and environmental indicators and high mortality rates from chronic kidney disease (CKD) in municipalities of Guatemala. An ecological study of municipal-level factors associated with CKD mortality in Guatemala was conducted. Crude mortality rates were calculated for the 2009–2019 period for each of the country’s 340 municipalities, by gender and age groups. Municipal-level social and environmental indicators were used as independent variables. Linear regression was used for bivariate and multivariate analysis. A total of 28,723 deaths from CKD were documented for the 2009–2019 period. Average crude mortality rate for …

Adult Asthma Associated With Roadway Density And Housing In Rural Appalachia: The Mountain Air Project (Map)., W Jay Christian, John Flunker, Beverly May, Susan Westneat, Wayne T Sanderson, Nancy Schoenberg, Steven R Browning

UK CARES Faculty Publications

BACKGROUND: Appalachian Kentucky is a rural area with a high prevalence of asthma among adults. The relative contribution of environmental exposures in the etiology of adult asthma in these populations has been understudied.

OBJECTIVE: This manuscript describes the aims, study design, methods, and characteristics of participants for the Mountain Air Project (MAP), and focuses on associations between small area environmental exposures, including roadways and mining operations, and lifetime and current asthma in adults.

METHODS: A cohort of residents, aged 21 and older, in two Kentucky counties, was enrolled in a community-based, cross-sectional study. Stratified cluster sampling was used to select …

Extreme Weather And Melioidosis: An Endemic Tropical Disease In Penampang District Of Sabah, Malaysia, Sam Froze Jiee, Kai Joo Lim, Daryl Sin Choon Vui, Dina Peter Marius, Nurul Syafiqah Illyana, Anisah Jantim

Journal of Health Research

Background: Melioidosis is a fatal, but preventable communicable disease that is endemic in several parts of the world, including the state of Sabah, Malaysia, which is located in the northern part of Borneo Island. Flooding is one of the most regular natural disasters affecting some parts of Malaysia, including Sabah. The main aim of this study was to determine if rainfall and floods were significant risk factors contributing to the substantial burden of melioidosis in the Penampang district from 2015 to 2020.

Method: We analyzed 64 culture-confirmed cases of melioidosis in the Penampang district, Sabah, between 2015 and 2020 to …

The Association Between Time Spent On Screens And Reading With Myopia, Premyopia And Ocular Biometric And Anthropometric Measures In 6- To 7-Year-Old Schoolchildren In Ireland, Síofra Harrington, Veronica O'Dwyer

Articles

Purpose More time spent on near tasks has consistently been associated with the promotion of myopia. The World Health Organization advises limiting daily screentime to less than 2 h for children aged five and over. This study explored the relationship between time spent on screens and reading/writing with refractive status, ocular biometric and anthropometric factors in 6-to 7-year- olds in Ireland.

Methods Participants were 723 schoolchildren (377 boys [51.8%]), mean age 7.08 (0.45) years. The examination included cycloplegic autorefraction (1% cyclopentolate hydrochloride), ocular biometry (Zeiss IOLMaster), height (cm) and weight (kg). Screentime and reading/writing time were reported by parents/legal guardians …

Highly Pathogenic Avian Influenza, Andrew N. Rowan, Kathleen Rowan

WellBeing News

The avian flu virus was the agent that caused the devastating worldwide influenza pandemic in 2018 that killed an estimated 50-100 million people, and health authorities continue to pay close attention to periodic outbreaks of avian flu. Currently, an H5N1 influenza virus is leading to millions of wild birds and domestic poultry deaths. Recently, this virus spread in a mink farm in Spain, raising the stakes that it might be able to spread among humans. While the current avian flu pandemic is a major economic problem for global farms and a major animal welfare concern for domestic poultry and wild …

The Effect Of An Educational Handout On Knowledge, Awareness And Attitudes Of Pre-Exposure Prophylaxis (Prep) Among Participants At A Needle And Syringe Exchange Site, Mckenzie Buckel

DNP Projects

Background: In 2018, the total number of HIV cases in the United States was 1.2 million. Almost 186,500 of these cases were attributed to intravenous drug use. With the adherence to pre-exposure prophylaxis (PrEP) there is approximately a 49% decrease in the rates of HIV among people who inject drugs and the most significant barrier to PrEP among this population is a lack of awareness and knowledge.

Objective: The purpose of this study was to determine participants’ of a needle and syringe exchange site knowledge, awareness and attitudes of PrEP after reviewing an educational handout about PrEP.

Methods: A quasi …

Identification Of Novel Biosynthetic Gene Clusters Encoding For Polyketide/Nrps-Producing Chemotherapeutic Compounds From Marine-Derived Streptomyces Hygroscopicus From A Marine Sanctuary, Hannah Ruth Flaherty

Honors Theses and Capstones

Nearly one out of six deaths in 2020, around ten million people, were caused by cancer, making it a leading cause of death worldwide (WHO, 2022). This major public health issue, in addition to the rise of multidrug-resistant (MDR) pathogens, provides a high demand for the discovery of new pharmaceutical drugs to be used clinically to treat these conditions. The Streptomyces genus accounts to produce 39% of all microbial metabolites currently approved for human health, indicating its potential as an important species to study for antimicrobial and anticancer agents. The long linear genome of Streptomyces contains specialized sequences known as …