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Clinical Epidemiology Commons

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Full-Text Articles in Clinical Epidemiology

Circulating Calcium, Phosphorus, And Parathyroid Hormone And Aggressive Prostate Cancer In The North Carolina-Louisiana Prostate Cancer Project, Brittany Crawford Apr 2020

Circulating Calcium, Phosphorus, And Parathyroid Hormone And Aggressive Prostate Cancer In The North Carolina-Louisiana Prostate Cancer Project, Brittany Crawford

Theses and Dissertations

Prostate cancer is the most commonly diagnosed cancer among men in the United States. Despite improvements in screening, diagnostic methods, and treatment, African-American men have an increased risk of total and aggressive prostate cancer. In recent years, a growing body of evidence linking biomarkers of calcium and parathyroid hormone (PTH) to prostate cancer development has emerged. Circulating calcium, phosphorus, and PTH are homeostatically related. Prior studies linking prostate cancer and circulating calcium and PTH have produced inconclusive results, and no studies have examined the association between serum phosphorus and prostate cancer. The present study examined the relationship between circulating calcium, …


The Impact Of Psychosocial, Clinical, And Neighborhood Factors On Inflammatory Outcomes Among African American Women, Malcolm Seth Bevel Apr 2020

The Impact Of Psychosocial, Clinical, And Neighborhood Factors On Inflammatory Outcomes Among African American Women, Malcolm Seth Bevel

Theses and Dissertations

Inflammatory-related chronic diseases are disparagingly prevalent among African Americans in the United States, particularly in the Southeastern region. Access to community gardens shows promise in mitigating chronic disease outcomes, despite multiple barriers to physical activity and diet among underserved populations. We seek to determine if psychosocial or clinical factors mediate the association between the treatment effect of a healthy lifestyle intervention and inflammatory biomarker levels among African American women, respectively. We also seek to analyze the relationship between residing in a food desert/swamp and inflammatory biomarker levels, while gaining a qualitative perspective about community garden access among African American women. …


The Interaction Between Caffeine Consumption, Alcohol Use, And Amount Of Sleep On Bone Health, Haley Davis-Martin Apr 2020

The Interaction Between Caffeine Consumption, Alcohol Use, And Amount Of Sleep On Bone Health, Haley Davis-Martin

Theses and Dissertations

Using cross-sectional data from the 2009-2010 and 2013-2014 NHANES surveys we examined potential interaction between caffeine consumption, alcohol use, and sleep and its relation to bone health, measured using bone mineral density (BMD). The study population consisted of 2,405 individuals at least 40 years old who were not taking any medications or hormones that would affect bone mineral density. Several factors such as smoking status, exercise, dietary intake of calcium, dietary intake of vitamin D, dietary intake of phosphorus, presence of arthritis, age, gender and race were considered in this project. We found a statistically significant negative linear relationships between …


Surveying Tuberculosis Screening Practices Of South Carolina Hospital Employees, Tamara T. Carree Apr 2020

Surveying Tuberculosis Screening Practices Of South Carolina Hospital Employees, Tamara T. Carree

Theses and Dissertations

BACKGROUND: Every year tuberculosis (TB) causes over 10 millions of people globally and in recent years has caused over 9,000 cases annually in the United States. TB can be transmitted in hospital settings, and South Carolina hospitals, like hospitals elsewhere in the country maintain a responsibility to test their employees for this disease. Nosocomial infections of active TB among patients and healthcare workers can be burdensome on hospital resources. Testing healthcare workers and implementing prevention strategies are examples of administrative controls provided in the 2005 guidelines by the Centers for Disease Control and Prevention (CDC). Implementation of administrative controls are …


An Examination Between Neighborhood Characteristics And Alzheimer’S Disease And Related Dementias And Caregiver Mental Health In South Carolina, Dana Mahmoud Alhasan Apr 2020

An Examination Between Neighborhood Characteristics And Alzheimer’S Disease And Related Dementias And Caregiver Mental Health In South Carolina, Dana Mahmoud Alhasan

Theses and Dissertations

Research has examined the relationship between neighborhood environments and cognitive decline, yet few have investigated the role of neighborhood characteristics specifically on incident Alzheimer’s disease and related dementias (ADRD), on severity of Alzheimer’s disease (AD) including neuropsychiatric symptoms (NPS), and on caregiver mental health including depressive symptoms. This dissertation aimed to 1) ecologically examine the geographic distribution of ADRD and investigate ecologic associations between census-tract neighborhood characteristics and diagnosed ADRD case incidence from 2010-2014 in the South Carolina (SC) Alzheimer’s Disease Registry; 2) estimate the cross-sectional association between neighborhood characteristics and NPS among those with AD in 2010 in SC; …