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Maternal and Child Health

Pregnancy

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Full-Text Articles in Public Health

The Association Between Maternal Obesity And Fetal Size For Gestational Age In Singletons And Twins, Shohi Prajapati Jul 2019

The Association Between Maternal Obesity And Fetal Size For Gestational Age In Singletons And Twins, Shohi Prajapati

Electronic Thesis and Dissertation Repository

Maternal obesity and multiple births have adverse effects on fetal growth; prevalence of both are increasing in Canada. We explored associations between maternal obesity and infant size for gestational age using data from a London perinatal database. Birthweight for gestational age was assessed using standards published by Robertson (2002) to classify Small for Gestational Age (SGA) and Large for Gestational Age (LGA) in 30396 singletons and 1346 twins. Associations were estimated using logistic regression for singletons and the GEE extension of logistic regression for twins. Increased maternal pre-pregnancy BMI was statistically significantly associated with decreased odds of SGA in singletons …


Antenatal Depressive Symptoms And Antidepressant Use In Pregnancy, Jerry Yu-Hsiang Chen Feb 2016

Antenatal Depressive Symptoms And Antidepressant Use In Pregnancy, Jerry Yu-Hsiang Chen

Electronic Thesis and Dissertation Repository

Review of the current literature reveals inconsistent findings on potential associations between antidepressant use during pregnancy and adverse fetal and child health and development. This study aims to examine the effect of antenatal SSRI exposure on several neonatal (preterm birth, small- and large-for-gestational age, Apgar score, and neonatal intensive care unit admission) and child developmental outcomes (measured by Ages and Stages Questionnaire) while controlling for confounding by indication. Data were obtained from the Prenatal Health Project, a longitudinal cohort study of 2,357 women in London, Ontario. Results from univariable analysis discovered that infants exposed to in utero SSRIs were more …


Population-Based Placental Weight Ratio Distributions And Determinants Of Placental Weight Ratios, Erin M. Macdonald Jul 2012

Population-Based Placental Weight Ratio Distributions And Determinants Of Placental Weight Ratios, Erin M. Macdonald

Electronic Thesis and Dissertation Repository

The placental weight ratio (PWR) is a common proxy for the balance between fetal and placental growth, and is defined as the placental weight over the birth weight. The objectives were (1a) to establish PWR distributions by gestational age for the overall population and (1b) for small, average and large for gestational age infants (SGA, AGA, LGA) and (2) to determine what pregnancy related conditions were associated with the PWR. The data were obtained using a hospital based retrospective cohort. Nonparametric quantile regression was used for the first and multinomial logistic regression for the second objective. The results show how …