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Inflammation And Acute Traffic-Related Air Pollution Exposures Among A Cohort Of Youth With Type 1 Diabetes, Robin C. Puett, Jeff D. Yanosky, Murray A. Mittleman, Jessica Montresor-Lopez, Ronny A. Bell, Tessa L. Crumee, Dana Dabeleae, Lawrence M. Dolan, Ralph B. D'Agostino Jr, Santica M. Marcovina, Catherine Pihokeri, Kristi Reynolds, Elaine Urbina, Angela D. Liese
Inflammation And Acute Traffic-Related Air Pollution Exposures Among A Cohort Of Youth With Type 1 Diabetes, Robin C. Puett, Jeff D. Yanosky, Murray A. Mittleman, Jessica Montresor-Lopez, Ronny A. Bell, Tessa L. Crumee, Dana Dabeleae, Lawrence M. Dolan, Ralph B. D'Agostino Jr, Santica M. Marcovina, Catherine Pihokeri, Kristi Reynolds, Elaine Urbina, Angela D. Liese
Faculty Publications
Background: Evidence remains equivocal regarding the association of inflammation, a precursor to cardiovascular disease, and acute exposures to ambient air pollution from traffic-related particulate matter. Though youth with type 1 diabetes are at higher risk for cardiovascular disease, the relationship of inflammation and ambient air pollution exposures in this population has received little attention.
Objectives: Using five geographically diverse US sites from the racially- and ethnically-diverse SEARCH for Diabetes in Youth Cohort, we examined the relationship of acute exposures to PM2.5 mass, Atmospheric Dispersion Modeling System (ADMS)-Roads traffic-related PM concentrations near roadways, and elemental carbon (EC) with biomarkers of inflammation …