Behavior and Behavior Mechanisms Commons^™

Development Of A Binge-Like Eating Animal Model Using Foods Of Varying Palatability: Effects Of The Catecholamine Uptake Blocker Lisdexamfetamine, Ariba Memon

Honors Scholar Theses

Binge Eating Disorder (BED) is a psychiatric disorder that is characterized by the consumption of an excessive amount of food in a short period of time despite not being hungry. Numerous animal models have been developed that can induce binge-like eating behavior through limited access to a highly palatable food. One such model utilizes Cadbury’s milk chocolate that is very successful in inducing binge-like eating behavior in both male and female rats. Lisdexamfetamine (LDX), a d-amphetamine prodrug and the only FDA approved pharmaceutical treatment for BED, has been shown to significantly reduce chocolate consumption in the chocolate binge-like animal model. …