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Full-Text Articles in Behavior and Behavior Mechanisms

Development Of A Binge-Like Eating Animal Model Using Foods Of Varying Palatability: Effects Of The Catecholamine Uptake Blocker Lisdexamfetamine, Ariba Memon May 2021

Development Of A Binge-Like Eating Animal Model Using Foods Of Varying Palatability: Effects Of The Catecholamine Uptake Blocker Lisdexamfetamine, Ariba Memon

Honors Scholar Theses

Binge Eating Disorder (BED) is a psychiatric disorder that is characterized by the consumption of an excessive amount of food in a short period of time despite not being hungry. Numerous animal models have been developed that can induce binge-like eating behavior through limited access to a highly palatable food. One such model utilizes Cadbury’s milk chocolate that is very successful in inducing binge-like eating behavior in both male and female rats. Lisdexamfetamine (LDX), a d-amphetamine prodrug and the only FDA approved pharmaceutical treatment for BED, has been shown to significantly reduce chocolate consumption in the chocolate binge-like animal model. …


Assessing Rat Behavioral Response To Novelty, Neha Mathew Apr 2021

Assessing Rat Behavioral Response To Novelty, Neha Mathew

Honors Scholar Theses

The hippocampus is the part of the brain that is involved in memory and navigation. Neurons in the hippocampus, known as place cells, fire in specific locations within this region of the brain as the subject navigates through their environment. As these cells fire, they create a map-like representation of this environment. However if the environment is altered in any way, the place cell firing pattern is adjusted to incorporate this new information. This adjustment will inevitably cause subjects to take more time to complete their task. The goal of our testing was to assess how various manipulations, both spatial …