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Full-Text Articles in Behavior and Behavior Mechanisms

Theta And Learning: Dorsal And Ventral Hippocampal Theta Oscillation Respond Differently To Learning, Gregory N. Newman May 2014

Theta And Learning: Dorsal And Ventral Hippocampal Theta Oscillation Respond Differently To Learning, Gregory N. Newman

Honors Scholar Theses

Rhythmic oscillations within the hippocampus are thought to synchronize various subregions during learning, maximizing efficiency of the neural circuits. In rats, the most prominent oscillation is hippocampal theta. Theta is known to be modulated by an animal’s velocity, but it has also been shown to change in response to cognitive demands. To determine if theta is important for learning and memory, EEG recordings were examined for changes in theta related to the decision point of a spatial or non-spatial T-maze task. Additionally, a straight runway served as a control to verify the consistent relationship between velocity and theta during a …


The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn May 2014

The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn

Honors Scholar Theses

Substantial evidence has shown that dopamine (DA), particularly in the nucleus accumbens (NAc), is involved in behavioral activation and effort-related processes, such as overcoming work related response costs. Interference with accumbens DA transmission through administration of the vesicular monoamine transportor-2 (VMAT-2) inhibitor tetrabenazine (TBZ) produces an alteration of response allocation in the concurrent FR5/chow choice procedure, biasing animals toward the lower effort alternative. It has been suggested that these drug-induced shifts in effort-related choice behavior seen in rodents are analogous to symptoms such as psychomotor retardation, anergia, and fatigue, which can be observed in people with depression and other related …