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Full-Text Articles in Behavior and Behavior Mechanisms

Dietary Probiotic Supplement Attenuates Methamphetamine-Induced Conditioned Place Preference In Female Sprague-Dawley Rats, Kristen Powell Jun 2024

Dietary Probiotic Supplement Attenuates Methamphetamine-Induced Conditioned Place Preference In Female Sprague-Dawley Rats, Kristen Powell

Masters Theses

Substance use disorders (SUD) represent a global public health crisis with limited effective treatment options. Recent findings implicate the gut microbiome and gut/brain axis in the pathophysiology of SUDs. Several preclinical studies have established that psychostimulants alter gut microbiome composition, but no published studies have assessed behavioral effects of dietary probiotic supplements on drug-induced behavioral changes. This study utilized rodent conditioned place preference (CPP) as a behavioral index of conditioned drug reward to determine if a dietary probiotic supplement alters the behavioral effects of (+)-methamphetamine (METH). Fifty-four adult female Sprague-Dawley rats were randomly assigned to receive either a standard rodent …


Addressing Common Mental Health Issues Prevalent Among Honors College Students, Steven Pham Aug 2017

Addressing Common Mental Health Issues Prevalent Among Honors College Students, Steven Pham

Honors Theses

The prevalence and severity of mental health disorders on college campuses has been increasing nationwide. This review aims to address some of the prevalent mental health issues that continuously plague college students today. Recent trends in college student mental health are analyzed as well as literature regarding common disorders including depression, anxiety, and bipolar disorder. A comparison of honors and non-honors students is provided to contribute to an otherwise lacking area of research surrounding honors student populations. Effective practices and policies for colleges and universities to incorporate into their counseling services are also considered, with viable goals centering on the …


Effects Of Low Dose Mixtures Of 3,4-Methylenedioxypyrovalerone And Cocaine On Locomotor Activity And Brain Monoamine Content In Sprague-Dawley Rats, Robert J. Kohler Jun 2017

Effects Of Low Dose Mixtures Of 3,4-Methylenedioxypyrovalerone And Cocaine On Locomotor Activity And Brain Monoamine Content In Sprague-Dawley Rats, Robert J. Kohler

Masters Theses

Synthetic cathinones, known as “bath salts” on the illicit drug market, pose a significant and growing public health concern. 3,4-Methylenedioxypyrovalerone (MDPV), one of several popular constituents of the illicit bath salts, produces similar pharmacological actions to cocaine, albeit with greater potency. The present study sought to characterize behavioral and neurochemical effects of repeated exposure to MDPV alone and in combination with cocaine. Male Sprague-Dawley rats were randomly assigned to one of four treatments: 1 mg/kg MDPV, 5 mg/kg cocaine, 1 mg/kg MDPV + 5 mg/kg cocaine, or saline. Locomotor activity was assessed for one hour immediately before and one hour …


Piloting A Screening Tool For Eating And Eating-Related Behavior, Michael N. Reynolds Jun 2016

Piloting A Screening Tool For Eating And Eating-Related Behavior, Michael N. Reynolds

Dissertations

Obesity is a common medical condition associated with negative health and social outcomes. Obesity has a primary malleable behavioral cause, eating more calories than are metabolized. While metabolic rate is malleable with exercise, eating can more quickly add calories than exercising can subtract them. In the past, behavioral weight-loss treatment studies relied on multi-component package interventions that have shown reliable patterns of participant weight-loss during treatment and weight-regain in follow-up. Those findings could be conceptualized as an ABA withdrawal design, eating behavior returns to baseline after the prosthetic contingencies of the treatment study are withdrawn. We must develop ways to …


Impulsive Choice In Unmedicated And Medicated Children Diagnosed With Adhd: Examining The Variables Of Reward Type And Adhd Subtype, Nicole Henriksen Apr 2014

Impulsive Choice In Unmedicated And Medicated Children Diagnosed With Adhd: Examining The Variables Of Reward Type And Adhd Subtype, Nicole Henriksen

Dissertations

Developmentally inappropriate and impairing impulsive behaviors are often seen in attention-deficit/hyperactivity disorder (ADHD). One method for objectively assessing impulsivity is the Choice-Delay Task (C-DT) which presents repeated opportunities to choose between a smaller, sooner (SS) or larger, later (LL) reward. A preference for the SS reward that results in less total reward is considered impulsive. Many studies have found that participants diagnosed with ADHD choose the SS reward more than typical controls. However, less is known about the effects of different types of rewards, or the comparative performance of certain subgroups, such as children diagnosed with ADHD Predominantly Inattentive Type …


The Acute Effects Of Cocaine In Pigeons Performing Under A Progressive-Ratio Schedule, Claudia Ann Jones Aug 1993

The Acute Effects Of Cocaine In Pigeons Performing Under A Progressive-Ratio Schedule, Claudia Ann Jones

Masters Theses

Although the progressive-ratio (PR) schedule has been used frequently to quantify the reinforcing effectiveness of self-administered drugs, it has seldom been used to examine the effects of drugs on food-maintained behavior and has never been used to evaluate the effects of cocaine on such behavior. In the present study, the effects of acute administrations of cocaine were evaluated in pigeons responding under a PR schedule of food delivery. Overall, cocaine produced a dose-dependent effect on food-maintained behavior. In general, acute administrations of cocaine at 0.56 to 3.2 mg/kg increased breaking points, whereas doses above 5.6 mg/kg decreased breaking points. Low …