Psychiatry and Psychology Commons^™

Depression And Its Associated Factors: Perceived Stress, Social Support, Substance Use And Related Sociodemographic Risk Factors In Medical School Residents In Nairobi, Kenya, Sayed Shah Nur Hussein Shah, Ahmed Laving, Violet Caroline Okech-Helu, Manasi Kumar

Brain and Mind Institute

Abstract: Background: Little data exists regarding depression and its associated factors in medical residents and doctors in Sub-Saharan Africa. Residents are at high risk of developing depression owing to the stressful nature of their medical practice and academic training. Depression in medical residents leads to decreased clinical efficiency, and poor academic performance; it can also lead to substance abuse and suicide. Our primary aim was to measure depression prevalence among medical residents in Kenya’s largest national teaching and referral hospital. Secondary aims were to describe how depression was associated with perceived stress, perceived social support, substance use, and educational environment. …

Mapping Services At Two Nairobi County Primary Health Facilities: Identifying Challenges And Opportunities In Integrated Mental Health Care As A Universal Health Coverage (Uhc) Priority, Manasi Kumar, Vincent Nyongesa, Martha Kagoya, Byamah B. Mutamba,, Beatrice Amugune, Neha S. Krishnam, Grace Nduku Wambua, Inge Petersen, Onesmus Gachuno, Shekhar Saxena

Brain and Mind Institute

Abstract: Introduction There is a need to scale-up mental health service provision in primary health care. The current extent of integration of mental health in primary care is pertinent to promoting and augmenting mental health at this level. We describe a facility mapping exercise conducted in two low-income/primary health facilities in Kenya to identify existing barriers and facilitators in the delivery of mental health services in general and specifically for peripartum adolescents in primary health care as well as available service resources, cadres, and developmental partners on the ground.

Method and measures This study utilized a qualitative evidence synthesis through …

Routine Outcome Measurement In Adolescents Seeking Mental Health Services: Standardization Of Honosca In Kenyan Sample, Grace Nduku Wambua, Manasi Kumar, Fredrik Falkenström, Pim Cuijpers

Brain and Mind Institute

Abstract: Background The evaluation of treatment outcomes is important for service providers to assess if there is improvement or not. The Health of the Nation Outcome Scales for Children and Adolescents (HoNOSCA) was developed for this use in child and adolescent mental health services. Outcome measurement in routine mental health services is limited. This paper evaluates the psychometric properties of the self and clinician rated versions of the HoNOSCA for routine use in child and adolescent mental health services in Kenya.

Methods Using a prospective design, the clinician- and self-rated versions of the HoNOSCA and the Paediatric Symptom Checklist (PSC) …

Mental Health Service Preferences Of Patients And Providers: A Scoping Review Of Conjoint Analysis And Discrete Choice Experiments From Global Public Health Literature Over The Last 20 Years (1999–2019), Anna Larsen, Albert Tele, Manasi Kumar

Brain and Mind Institute

Abstract: Background: In designing, adapting, and integrating mental health interventions, it is pertinent to understand patients’ needs and their own perceptions and values in receiving care. Conjoint analysis (CA) and discrete choice experiments (DCEs) are survey-based preference-elicitation approaches that, when applied to healthcare settings, offer opportunities to quantify and rank the healthcare-related choices of patients, providers, and other stakeholders. However, a knowledge gap exists in characterizing the extent to which DCEs/CA have been used in designing mental health services for patients and providers. Methods: We performed a scoping review from the past 20 years (2009–2019) to identify and describe applications …

Is There An Optimal Screening Tool For Identifying Perinatal Depression Within Clinical Settings Of Sub-Saharan Africa?, Anna Larsen, Jillian Pintye, Amritha Bhat, Manasi Kumar, John Kinuthia, Pamela Y. Collins, Grace John Stewart

Brain and Mind Institute

Abstract: Depression is a leading cause of maternal morbidity and mortality worldwide and the most common complication of the perinatal period. Women in sub-Saharan Africa (SSA) are disproportionately impacted by perinatal depression. Maternal and child health (MCH) clinics are widely attended in SSA, offering a potential access point for depression screening. Yet, selection of optimal depression screening instruments for use within MCH clinics in SSA remains unclear. We synthesized evidence depicting relative strength of perinatal depression screening scales for use among African perinatal women within four evaluation domains: 1) diagnostic performance, 2) cultural adaptation, 3) feasibility and ease of implementation, …

Use Of Multidimensional Item Response Theory Methods For Dementia Prevalence Prediction: An Example Using The Health And Retirement Survey And The Aging, Demographics, And Memory Study, Manasi Kumar, Gbd 2019 Dementia Collaborators

Brain and Mind Institute

Abstract: Background: Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic evaluations of dementia prevalence are prohibitively resource-intensive in many settings. However, validation samples from nationally representative surveys allow for the development of algorithms for the prediction of dementia prevalence nationally. Methods: Using cognitive testing data and data on functional limitations from Wave A (2001–2003) of the ADAMS study (n=744) and the 2000 wave of the HRS study (n=6358) we estimated a two-dimensional item response theory model to calculate cognition and function scores for all individuals over 70. Based on diagnostic information …

Psychosocial Risk Factors And Cardiovascular Disease And Death In A Population-Based Cohort From 21 Low-, Middle-, And High-Income Countries, Ailiana Santosa, Annika Rosengren, Chinthanie Ramasundarahettige, Sumathy Rangarajan, Jephat Chifamba, Scott A. Lear, Paul Poirier, Karen E. Yeates, Rita Yusuf, Romaina Iqbal

Community Health Sciences

Importance: Stress may increase the risk of cardiovascular disease (CVD). Most studies on stress and CVD have been conducted in high-income Western countries, but whether stress is associated with CVD in other settings has been less well studied.
Objective: To investigate the association of a composite measure of psychosocial stress and the development of CVD events and mortality in a large prospective study involving populations from 21 high-, middle-, and low-income countries across 5 continents.
Design, setting, and participants: This population-based cohort study used data from the Prospective Urban Rural Epidemiology study, collected between January 2003 and March 2021. Participants …

Search For Dark Matter Produced In Association With A Standard Model Higgs Boson Decaying Into B-Quarks Using The Full Run 2 Dataset From The Atlas Detector, Georges Aad, B Abbott, Dc Abbott, A Abed Abud, Kira Abeling, Deshan Kavishka Abhayasinghe, Sh Abidi, Os Abouzeid, Halina Abramowic, Manasi Kumar

Brain and Mind Institute

Abstract: The production of dark matter in association with Higgs bosons is predicted in several extensions of the Standard Model. An exploration of such scenarios is presented, considering final states with missing transverse momentum and b-tagged jets consistent with a Higgs boson. The analysis uses proton-proton collision data at a centre-of-mass energy of 13 TeV recorded by the ATLAS experiment at the LHC during Run 2, amounting to an integrated luminosity of 139 fb−1 . The analysis, when compared with previous searches, benefits from a larger dataset, but also has further improvements providing sensitivity to a wider spectrum of signal …

The Path To Global Equity In Mental Health Care In The Context Of Covid-19, Lola Kola, Brandon A. Kohrt, Bibhav Acharya, Byamah B. Mutamba, Christian Kieling, Manasi Kumar, Charlene Sunkel, Wufang Zhang, Charlotte Hanlon

Brain and Mind Institute

The theme of the 2021 World Mental Health Day is “Mental Health in an Unequal World”, highlighting unequal access to mental health care across the world. This situation has been further worsened by governmental and public responses to the COVID-19 pandemic. The response of many high-income countries (HICs) and institutions to the pandemic has been the reverse of equity, exemplified by inequitable access to COVID-19 vaccines and widening inequities in wealth.1 A crucial consideration in this context is the imbalance in social and economic factors that shape onset and outcomes of mental health across communities and countries.2 Looking through a …

Psychological Autopsy Study And Risk Factors For Suicide In Muslim Countries, S M Yasir Arafat, Murad M. Khan, Vikas Menon, Syeda Ayat-E-Zainab Ali, Mohsen Rezaeian, Sheikh Shoib

Department of Psychiatry

Background: Suicide and risk factors have been poorly studied in the Muslim-majority countries that hinder the formulation of prevention strategies and affect suicide prevention eventually.
Objectives: We aimed at identifying and analyzing the psychological autopsy studies assessing the risk factors for suicide conducted in Muslim-majority countries.
Methods: We did a search to trace all the available psychological autopsy studies in the Muslim countries with the search term "psychological autopsy study in Muslim countries." We also checked the available bibliographies to identify the psychological autopsy studies in the Muslim countries so that all the possible studies could be included.
Results: Out …

Global, Regional, And National Mortality Among Young People Aged 10–24 Years, 1950–2019: A Systematic Analysis For The Global Burden Of Disease Study 2019, Joseph L. Ward, Peter S S. Azzopardi, Kate Louise Francis, John S S. Santelli, Vegard Skirbekk, Susan M. Sawyer, Nicholas J. Kassebaum, Ali H. Mokdad, Simon I. Hay, Manasi Kumar

Brain and Mind Institute

Summary: Background Documentation of patterns and long-term trends in mortality in young people, which reflect huge changes in demographic and social determinants of adolescent health, enables identification of global investment priorities for this age group. We aimed to analyse data on the number of deaths, years of life lost, and mortality rates by sex and age group in people aged 10–24 years in 204 countries and territories from 1950 to 2019 by use of estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods We report trends in estimated total numbers of deaths and mortality …

Fears And Barriers: Problems In Breast Cancer Diagnosis And Treatment In Pakistan, Sidra Saeed, Muhammad Asim, Malik Muhammad Sohail

Community Health Sciences

Background: Women in Pakistan lack appropriate awareness about diagnosis and treatment for breast cancer due to a range of multifaceted barriers. There is a dearth of literature examining the socio-cultural factors that inhibit women from breast cancer screening, diagnosis and treatment in Punjab, Pakistan. Addressing this gap, this qualitative study sought to identify and explore the barriers that hinder women from seeking timely screening and treatment.
Methods: In this process 45 women (age = 18-50 years) with breast cancer were purposively sampled and interviewed from the Punjab Institute of Nuclear Medicine (PINUM) hospital, Faisalabad, Pakistan.
Results: An inductive approach was …

Sexual Violence And Suicide In Bangladesh, S M Yasir Arafat, Murad M. Khan

Department of Psychiatry

No abstract provided.

Peer Victimization And Experiences Of Violence At School And At Home Among School Age Children With Disabilities In Pakistan And Afghanistan, Rozina Somani, Julienne Corboz, Rozina Karmaliani, Esnat D. Chirwa, Judith Mcfarlane, Hussain Maqbool Ahmed Khuwaja, Nargis Asad, Yasmeen Hassan Somani, Ingrid Van Der Heijden, Rachel Jewke

School of Nursing & Midwifery

Background: Children with disabilities are more likely to experience violence or injury at school and at home, but there is little evidence from Central Asia.
Objective: To describe the prevalence of disability and associations with peer violence perpetration and victimization, depression, corporal punishment, school performance and school attendance, among middle school children in Pakistan and Afghanistan.
Method: This is a secondary analysis of data gathered in the course of evaluations of interventions to prevent peer violence conducted in Pakistan and Afghanistan as part of the 'What Works to Prevent Violence against Women and Girls Global Programme'. In …

Risk Factors For Suicide In Bangladesh: Case-Control Psychological Autopsy Study, S M Yasir Arafat, M A. Mohit, Mohammad S I. Mullick, Russell Kabir, Murad M. Khan

Department of Psychiatry

Background: Suicide is an important, understudied public health problem in Bangladesh, where risk factors for suicide have not been investigated by case-control psychological autopsy study.
Aims: To identify the major risk factors for suicide in Dhaka, Bangladesh.
Methods: We designed a matched case-control psychological autopsy study. We conducted a semi-structured interview with the next-of-kin of 100 individuals who died by suicide and 100 living controls, matched for age, gender and area of residence. The study was conducted from July 2019 to July 2020.
Results: The odds ratios for the risk factors were 15.33 (95% CI, 4.76-49.30) for the presence of …