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Four Potential Criteria For Deciding When To Use Antidepressants Or Psychotherapy For Unipolar Depression: A Literature Review, Christopher Sharpley, Vicki Bitsika Sep 2012

Four Potential Criteria For Deciding When To Use Antidepressants Or Psychotherapy For Unipolar Depression: A Literature Review, Christopher Sharpley, Vicki Bitsika

Vicki Bitsika

Objective: To evaluate the literature supporting four potential criteria for deciding whether to use psychotherapy or pharmacology when treating depression.

Method: Literature review of the evidence from the last 10 years on presenting patient’s demographics, aetiology, comorbidity, and genetic factors, as predictors of treatment outcome efficacy.

Results: Demographic information has little support as a potential criteria for decision-making; aetiology (melancholic vs. non-melancholic) has significant support; presence of personality disorder comorbidity is unproven as a criterion but may have some value; genetic predisposition has the strongest evidence supporting it as a criteria for treatment decision-making.

Conclusion: Although some presenting cases will …


Variability In Anxiety And Depression Over Time Following Diagnosis In Patients With Prostate Cancer, Christoper Sharpley, David Christie, Vicki Bitsika Sep 2012

Variability In Anxiety And Depression Over Time Following Diagnosis In Patients With Prostate Cancer, Christoper Sharpley, David Christie, Vicki Bitsika

Vicki Bitsika

To determine the presence and nature of variability in anxiety and depression in patients with prostate cancer (PCa) over 3 years following diagnosis, 442 patients with PCa completed standardized anxiety and depression inventories via survey between 1 and 36 months after receiving their initial diagnosis. Data were analyzed from a series of 3-month cohorts, and results indicated that total scores and incidence of clinically significant anxiety and depression varied over time, but that this variability was restricted to specific subfactors of anxiety and depression. Provision of effective psychological treatment to patients with PCa is discussed.