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0482: Dr. Walter Freeman's Papers From Huntington State Hospital, 1897-1984, Marshall University Special Collections

Guides to Manuscript Collections

Please note: this collection does not contain individual patient hospital records or records about individuals who stayed here. The items in this collection come from a specific doctor who worked here and his research.

This collection consists of historical materials from the Huntington State Hospital during the period 1897 through 1984. The collection includes correspondence of hospital personnel and patients, administrative records, newspaper clippings, and a large number of photographs. Significant to the collection are files relating to transorbital lobotomies performed by Dr. Walter Freeman in the early 1950's as part of a larger lobotomy project in West Virginia. The …

Norm-Of-Reaction: Definition And Misinterpretation Of Animal Research, Steve A. Platt, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

The development of a phenotype is due to an interaction of the genotype with the environment. Two terms have been used to describe the outcome of this interaction, the norm-of-reaction and the reaction range. The first represents the theoretically limitless distribution of the phenotypes that may be expressed by a given genotype. The reaction range implies an upper and lower limit for phenotype expression possible from a given genotype. A critical distinction between the reaction range and the norm-of-reaction is that the norm-of-reaction is a statement of the conceivable interactions found but does not imply any predictability other than that …