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The Dogma Of Tissue Ischemia With Local Anesthetic And Epinephrine Use, Laura Morrissey

Capstone Showcase

Epinephrine is often combined with Lidocaine for local anesthetic use as it improves the duration and quality of Lidocaine and promotes wound hemostasis.^1-2 Despite these benefits, epinephrine has been historically contraindicated from being injected into fingers, toes, ears and the nose due to concern over the vasoconstrictive properties of epinephrine leading to ischemia in these end-arteriole areas.^3-7 However, there is very little documented evidence of this happening with epinephrine use.^5-13 An exhaustive review done by Denkler in 2001 reviewed 21 cases between 1889-2001 that involve epinephrine local injection prior to digit ischemia. However, none of these cases …