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James Madison University

Mec

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Full-Text Articles in Organisms

Identification Of The Staphylococcal Cassette Chromosome Mec (Sccmec) Element In Viral Fractions From Environmental Samples, Emily M. Pelto May 2015

Identification Of The Staphylococcal Cassette Chromosome Mec (Sccmec) Element In Viral Fractions From Environmental Samples, Emily M. Pelto

Senior Honors Projects, 2010-2019

Antibiotic resistance attributed to methicillin-resistant Staphylococcus aureus (MRSA) has become a growing concern over the last decade in both the healthcare and agricultural environment. This resistance is encoded by the gene mecA that is located on a mosaic, mobile genetic element called the Staphylococcal Cassette Chromosome mec (SCCmec) element. It is proposed that the transfer of the SCCmec element and resulting spread of resistance occur by transduction, the transfer of genetic material from bacterium to bacterium by a bacteriophage. Specifically, it is hypothesized that the transduction of this resistance is occurring in the agricultural setting. To test …