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Sexual Dimorphism Of Glomerular Capillary Morphology In Rats, Zackarias Coker
Sexual Dimorphism Of Glomerular Capillary Morphology In Rats, Zackarias Coker
Undergraduate Honors Theses
Chronic kidney disease (CKD) progresses faster in males than females; however, the underlying mechanisms remain poorly understood. Sex differences in glomerular capillary morphology has been hypothesized to contribute, in part, to the increased susceptibility to hypertension-induced renal injury and CKD progression in males, but this has not been investigated. The goal of the present study was to assess glomerular capillary morphology in male vs. female rats with intact kidneys and after uninephrectomy (UNX). We hypothesized that glomerular capillary radii (RCAP) and length (LCAP) would be greater in male rats.
Male (n=4) and female (n=4) with intact …