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Articles 1 - 6 of 6
Full-Text Articles in Organisms
Evaluation Of Tumor Necrosis Factor Alpha In Sleep-Deprived Menopausal- Induced Rats And The Impact On Bone Health, Nicole Ellsworth, Dwight Curry Iii, Cj Deleon, Frank Frisch
Evaluation Of Tumor Necrosis Factor Alpha In Sleep-Deprived Menopausal- Induced Rats And The Impact On Bone Health, Nicole Ellsworth, Dwight Curry Iii, Cj Deleon, Frank Frisch
Student Scholar Symposium Abstracts and Posters
Post-menopausal osteoporosis as a consequence of estrogen depletion is a growing concern for women in the United States. As more women take on executive positions and experience sleep deprivation, there is the potential for up regulation of pro-inflammatory cytokines, such as tumor necrosis factor alpha. It follows that the homeostatic imbalance of osteoclastic and osteoblastic activity leads to a greater risk of disease. Bisphosphonates generally, and Zolendronate specifically works by decreasing the number of osteoclasts. This current study investigated the impact of Zolendronate on the concentrations of tumor necrosis factor alpha-type (TNFɑ) in 32 ovariectomized Wistar rats. Throughout a five …
Coccidioidomycosis: Medical And Spatio-Temporal Perspectives, Nikias Sarafoglou, Rafael Laniado-Laborin, Menas Kafatos
Coccidioidomycosis: Medical And Spatio-Temporal Perspectives, Nikias Sarafoglou, Rafael Laniado-Laborin, Menas Kafatos
Mathematics, Physics, and Computer Science Faculty Articles and Research
Coccidioidomycosis (CM) is a disease of major public health importance due to the challenges in its diagnosis and treatment. To understand CM requires the attributes of a multidisciplinary network analysis to appreciate the complexity of the medical, the environmental and the social issues involved: public health, public policy, geology, atmospheric science, agronomy, social sciences and finally humanities, all which provide insight into this population transformation.
In section 1 of this paper, we describe the CM-epidemiology, the clinical features, the diagnosis and finally the treatment.
In section 2, we highlight the most important contributions and controversies in the history of the …
Determining Remote Sensing Spatial Resolution Requirements For The Monitoring Of Harmful Algal Blooms In The Great Lakes, John Lekki, Eric Deutsch, Michael Sayers, Karl Bosse, Robert Anderson, Roger Tokars, Reid W. Sawtell
Determining Remote Sensing Spatial Resolution Requirements For The Monitoring Of Harmful Algal Blooms In The Great Lakes, John Lekki, Eric Deutsch, Michael Sayers, Karl Bosse, Robert Anderson, Roger Tokars, Reid W. Sawtell
Michigan Tech Publications
Harmful algal blooms (HABs) have become a major health and environmental concern in the Great Lakes. In 2014, severe HABs prompted the State of Ohio to request NASA Glenn Research Center (GRC) to assist with monitoring algal blooms in Lake Erie. The most notable species of HAB is Microcystis aeruginosa, a hepatotoxin producing cyanobacteria that is responsible for liver complications for humans and other fauna that come in contact with these blooms. NASA GRC conducts semiweekly flights in order to gather up-to-date imagery regarding the blooms' spatial extents and concentrations. Airborne hyperspectral imagery is collected using two hyperspectral imagers, HSI-2 …
Network Analyses Of Glomerular Capillaries, Jason Cory Brunson, Justin Sardi, Mark Terasaki
Network Analyses Of Glomerular Capillaries, Jason Cory Brunson, Justin Sardi, Mark Terasaki
Biology and Medicine Through Mathematics Conference
No abstract provided.
Spatial-Temporal Variability Of In Situ Cyanobacteria Vertical Structure In Western Lake Erie: Implications For Remote Sensing Observations, Karl Bosse, Michael Sayers, Robert Shuchman, Gary L. Fahnenstiel, Steven A. Ruberg, David L. Fanslow, Dack G. Stuart, Thomas H. Johengen, Ashley M. Burtner
Spatial-Temporal Variability Of In Situ Cyanobacteria Vertical Structure In Western Lake Erie: Implications For Remote Sensing Observations, Karl Bosse, Michael Sayers, Robert Shuchman, Gary L. Fahnenstiel, Steven A. Ruberg, David L. Fanslow, Dack G. Stuart, Thomas H. Johengen, Ashley M. Burtner
Michigan Tech Publications
Remote sensing has provided expanded temporal and spatial range to the study of harmful algal blooms (cyanoHABs) in western Lake Erie, allowing for a greater understanding of bloom dynamics than is possible through in situ sampling. However, satellites are limited in their ability to specifically target cyanobacteria and can only observe the water within the first optical depth. This limits the ability of remote sensing to make conclusions about full water column cyanoHAB biomass if cyanobacteria are vertically stratified. FluoroProbe data were collected at nine stations across western Lake Erie in 2015 and 2016 and analyzed to characterize spatio-temporal variability …
Conformational Flexibility In The Enterovirus Rna Replication Platform, Meghan S. Warden, Kai Cai, Gabriel Cornilescu, Jordan E. Burke, Komala Ponniah, Samuel E. Butcher, Steven M. Pascal
Conformational Flexibility In The Enterovirus Rna Replication Platform, Meghan S. Warden, Kai Cai, Gabriel Cornilescu, Jordan E. Burke, Komala Ponniah, Samuel E. Butcher, Steven M. Pascal
Chemistry & Biochemistry Faculty Publications
A presumed RNA cloverleaf (5′CL), located at the 5′-most end of the noncoding region of the enterovirus genome, is the primary established site for initiation of genomic replication. Stem–loop B (SLB) and stem–loop D (SLD), the two largest stem–loops within the 5′CL, serve as recognition sites for protein interactions that are essential for replication. Here we present the solution structure of rhinovirus serotype 14 5′CL using a combination of nuclear magnetic resonance spectroscopy and small-angle X-ray scattering. In the absence of magnesium, the structure adopts an open, somewhat extended conformation. In the presence of magnesium, the structure compacts, bringing SLB …