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Geriatric Nursing Commons

Open Access. Powered by Scholars. Published by Universities.®

2013

Cohort Studies

Articles 1 - 2 of 2

Full-Text Articles in Geriatric Nursing

Efficacy Of A Vitamin/Nutriceutical Formulation For Moderate To Late Alzheimer’S Disease: A Placebo-Controlled Pilot Study, Ruth Remington, A Chan, Thomas Shea Feb 2013

Efficacy Of A Vitamin/Nutriceutical Formulation For Moderate To Late Alzheimer’S Disease: A Placebo-Controlled Pilot Study, Ruth Remington, A Chan, Thomas Shea

Ruth Remington

Recent studies demonstrated efficacy of a vitamin/ nutriceutical formulation (folate, vitamin B12, alpha-tocopherol, S-adenosyl methionine, N-acetyl cysteine, and acetyl-L-carnitine) for mild to moderate Alzheimer's disease. Herein, we tested the efficacy of this formulation in a small cohort of 12 institutionalized patients diagnosed with moderate-stage to later-stage Alzheimer's disease. Participants were randomly separated into treatment of placebo groups. Participants receiving the formulation demonstrated a clinically significant delay in decline in the Dementia Rating Scale and clock-drawing test as compared to those receiving placebo. Institutional caregivers reported approximately 30% improvement in the Neuropyschiatric Inventory and maintenance of performance in the Alzheimer's Disease …


The Clock-Drawing Test: Time For A Change?, A Chan, Ruth Remington, J Paskavitz, Thomas Shea Feb 2013

The Clock-Drawing Test: Time For A Change?, A Chan, Ruth Remington, J Paskavitz, Thomas Shea

Ruth Remington

Clock-drawing tests are simple and rapid screening devices for dementia. It was observed that individuals (" . . .make the clock read 12:45") or an analog prompt (" . . .quarter to 1"), whereas individuals >70 years of age showed improved performance with an analog prompt. The digital prompt has routinely been used to force participants to recode the prompt via conceptualization. Differential scoring across a range of ages has likely derived from the advent and increase of digital clocks with the younger segment of the population. This implies the need for as-yet undetermined alteration in the nature of prompts …