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Role Of The Serotonin Transporter Gene In Resilience To Stress And Trauma: An Integrative Review, Kosuke Niitsu
Role Of The Serotonin Transporter Gene In Resilience To Stress And Trauma: An Integrative Review, Kosuke Niitsu
Posters and Presentations: College of Nursing
Resilience is defined as a multi-dimensional dynamic concept of positive adaptation to stress and trauma. It is estimated that 38 - 52% of phenotypic variation in resilience among Americans is due to genetic variance. Among nine candidate genes associated with resilience, the promoter region of serotonin transporter gene (5- HTTLPR) is of increasing clinical interest. Accumulating evidence suggests those who carry the Short (S) allele of 5-HTTLPR may be at increased risk of developing psychopathology such as Post-Traumatic Stress Disorder (PTSD). However, little is known about whether S allele carriers are less resilient to stress and trauma compared to Long …
Five Dimensions Of Wellness And Predictors Of Cognitive Health Protection In Community Dwelling Older Adults: A Historical Collage Cohort Study, Kelley A. Strout Dr
Five Dimensions Of Wellness And Predictors Of Cognitive Health Protection In Community Dwelling Older Adults: A Historical Collage Cohort Study, Kelley A. Strout Dr
Nursing Faculty Scholarship
Wellness is associated with cognitive health protection; however, findings are limited because they only examine variable(s) within one dimension of wellness. This research examined the association between multiple dimensions of wellness and cognition among aging adults. The sample included 5,605 male and female community-dwelling adults 60 years and older. Four dimensions of wellness demonstrated a statistically significant higher mean difference in cognitively healthy older adults compared to cognitively impaired older adults, F(4, 5,595) = 47.57, p < .001. Emotional wellness demonstrated the strongest association with cognitive health, followed by physical and spiritual wellness, F(5, 5,372) = 50.35, p < .001. Future research is needed to examine the cognitive protective benefits of wellness using longitudinal, prospective designs that control for the potential temporal relationship between wellness and cognition.DOI: 10.1177/0898010114540322