Psychiatric and Mental Health Commons^™

Safety And Efficacy Of 112 Mg Intranasal Esketamine In Patients With Treatment-Resistant Depression: A Retrospective Observational Study From Outpatient Community Clinics, Kirsten Brinkmeier, Michael Kritzer, Brandon Doan, Cecilia Li, Nicholas Mischel

Medical Student Research Symposium

This retrospective study examined the safety and efficacy of 56, 84, and 112 mg intranasal (IN) esketamine via medical record review of 24 patients with treatment resistant depression (TRD). Doses ranged from 56 mg to 112 mg and were titrated across sessions to maximize individual response while considering tolerability. Treatment response was defined by reduction in average Patient Health Questionnaire-9 (PHQ-9) scores. Tolerability was defined by blood pressures at baseline, 40 minutes after, and 2 hours after drug administration. Patients ranged from 19 to 60 years old (average 38.87), and 15 (62.5%) were female. Patients received an average of 1 …

Examining The Adjustment, Acculturation, And Well-Being Of International Arab Students In The United States: Implications For Policy And Practice, Hassan A A Kh A A Arab

Wayne State University Dissertations

This paper explored Arab international students studying in the United States to see whether they face acculturation stress, adjustment, or well-being issues. I found that my sample (N=95) experienced moderately high well-being distress and acculturative stress. However, the sample showed resilience and positive adjustment in all aspects, psychological (M=34.7), social (M=38.5), and academic (M=37.4). Moreover, well-being score from a modified GHQ survey came with high SD, indicating some students were dealing with serious mental issues, while others were doing well (M=42.92, SD=5.52). The majority of my participants were males (74.7%), single (75.8%), and graduate students (50.5%). Chi-square analysis found a …

The Category Is: Body: A Pcsim Approach To Culture-Specific Bid Healing Programming For Bgcm, Gabriel A. Delong

Wayne State University Dissertations

Black gay cismen (BGCM) are among the highest population demographics to experience body image dissatisfaction (BID) and among the least likely to seek healing programming. Culture-specific experiences such as sexual racism have been linked to body image dissatisfaction among BGCM. While the harmful experiences of sexual racism have been studied among BGCM, body image healing programming continues to address the needs of predominantly White straight ciswomen. Additionally, medical mistrust, identity preservation, and culturally incongruent healing practices have been linked to reasons BGCM are reluctant to seek healing practices. This dissertation aims to address the gap in existing literature by employing …

A Systematic Review Of Digital Technology Use For The Treatment And Management Of Ptsd, Liam Browning, Arash Javanbakht, Imran Rashid

Medical Student Research Symposium

The COVID-19 pandemic led to rapid growth in telemental health services and investment in digital mental health technologies. Digital mental health technologies could expand access to mental health care in a time of increasing provider deficit by providing tools for expedited psychiatric symptom assessment and management. This systematic review explores the current evidence for the use of scalable digital treatment modalities, including virtual reality (VR), machine learning, wearables, mobile apps, and neurofeedback training in the diagnosis and treatment of PTSD. Our findings support the current literature suggesting VR interventions are efficacious for combat-related PTSD treatment and that conclusions of studies …

Why We Come: Investigating Virtual Clubhouse Engagement, Megan H. Price

Wayne State University Dissertations

Only a fraction of individuals living with serious mental illness (SMI) receive adequatetreatment. This study investigates members’ experiences of a virtual adaptation of the Clubhouse model, a psychosocial rehabilitation program. During the COVID-19 lockdowns, the virtual Clubhouse, referred to as virtual programming, was established to provide an alternative to the traditional brick-and-mortar Clubhouse. This qualitative inquiry utilizes a phenomenological approach to understand participant experiences of the virtual model, including factors related to motivation, recovery, and impact. Data was collected through semi-structured interviews with 15 members of a Clubhouse located in a large metropolitan city in the U.S. The interviews sought …

Slow Surgical Correction Affects More Than Just The Bowels, Emilia M. Clementi

Clinical Research in Practice: The Journal of Team Hippocrates

Reflection on how delayed colostomy reversal affects a patient's mental and physical well-being.

Demographic And Psychosocial Factors Associated With Suicide Mortality Among Childbearing-Aged Individuals: A Case-Control Study, Katerina A. Furman, Amy Loree Phd, Lyuba Gavrilova Bs, Leah Hecht Phd, Hsueh-Han Yeh, Frances Lynch, Brian Ahmedani, Rebecca Rossom, Anne Beck Phd, Yihe Daida Phd, Gregory Simon Md, Christine Lu Phd, Joslyn Westphal Mph, Ashii Owen-Smith Phd, Stephen Waring, Cathrine Frank Md

Medical Student Research Symposium

Objective: Examine pregnancy-related, demographic, psychosocial and healthcare utilization factors associated with suicide mortality among childbearing-aged women. Methods: Data from nine health care systems in the Mental Health Research Network were included. A case-control study design was used in which 290 childbearing-age women who died by suicide (cases) from 2000-2015 were matched with 2,900 childbearing-age women from the same healthcare system and enrolled during the same time period who did not die by suicide. Conditional logistic regression was used to analyze associations between patient characteristics and suicide. Results: Women who died by suicide were more likely to have mental health or …

Childhood-Onset Attention-Deficit/Hyperactivity Disorder Exacerbates Opioid Use Disorder Consequences: Mediation By Impulsive Phenotypes, Liam R. Browning, Ciara Cannoy, Tabitha E. H. Moses, Leslie H. Lundahl Phd, David M. Ledgerwood Phd, Mark K. Greenwald Phd

Medical Student Research Symposium

Background: Attention deficit hyperactivity disorder (ADHD) is highly prevalent and associated with opioid use disorder (OUD). Yet, little is known about the mechanisms by which ADHD (which is a heterogeneous construct/diagnosis) might alter the trajectory of OUD outcomes.

Aim: This cross-sectional study examines relationships between childhood ADHD (inferred as predating substance use) and the extent to which the effects of ADHD on lifetime heroin-use consequences are mediated by foreshortened time perspective and drug-use impulsivity.

Methods: Individuals who report heroin use (N=214) were screened using the Assessment of Hyperactivity and Attention (AHA), Impulsive Relapse Questionnaire (IRQ), Stanford Time Perception Inventory (STPI), …

Discharged Against Medical Advice In The Postpartum Period: Why Should We Care?, Gurbani Bedi Bs, Mariam Ayyash Md, Mscr, Monique Swain Md

Medical Student Research Symposium

Objective: To understand reasons and events surrounding postpartum discharges against medical advice (AMA) in an urban population in Detroit, Michigan.

Methods: A retrospective chart review was conducted looking at women who left AMA in the postpartum period from Henry Ford Hospital in Detroit, Michigan between 2013 and 2021.

Results: 111 women (0.18%) left AMA in the postpartum period between 2013 and 2021. 35.1% of women were Black, 53% were White, 11.7% were of other races. 4.5% of women had home births and were brought in by EMS shortly after delivery. 44.1% of women had preterm births. 35.1% delivered via cesarean …

The Biopsychosocial Model And Clinical Decision Science In The Age Of Black Lives Matter: A Clinical Reflection, Abdul-Rahman M. Suleiman, Samer Ilayan

Clinical Research in Practice: The Journal of Team Hippocrates

The author reflects on the biopsychosocial considerations of elevated blood pressure in teenage African American youth during the era of Black Lives Matter (BLM). Parallels are drawn between Dr. Engel’s biopsychosocial model and clinical decision science.

Chronic Use Of Non-Medical Abdominal Compressors: Medical And Psychological Implications, Sawsan Edriss, Bushra Azom, Manar Edriss, Mustafa Edriss, Ann-Cathrin Guertler, Eva Waineo Md, Diane L. Levine Md

Medical Student Research Symposium

The popularity of waist cinchers, shapewear, abdominal binders, corsets, and waist trainers has increased in the population. Although corsets have been part of western fashion since the 18th century, abdominal compressors remain in style even today. In 2018, sales for shapewear worldwide were estimated at 2.26 billion USD. 1 Despite its popularity, shapewear safety and medical effects have not been widely studied.

In 1968, “Pantygirdle Syndrome” was described, attributing vulvitis, urethritis, and urinary tract infections to materials used from the “pantygirdle”. 2 The article describes that the girdle caused gastrointestinal symptoms with diaphragmatic and stomach displacement causing gastro-esophageal reflux disease …

Mindfulness Therapy Is An Effective Adjunctive Treatment For Adolescents Living With Hiv, Samantha Rea

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising Webb L, Perry-Parrish C, Ellen J, Sibinga E. Mindfulness instruction for HIV-infected youth: a randomized controlled trial. AIDS Care. 2018;30(6):688–695. https://doi.org/10.1080/09540121.2017.1394434

Mental Health Service Utilization Among Urban Adolescents: The Roles Of Perceived Mental Health Problems, Attitudes Towards Professional Help, And Stigma, Yi Tak Tsang

Wayne State University Dissertations

Mental health among adolescents is widely acknowledged as a significant concern in the United States. Based on a national survey, Merikangas et al. (2010) found that among 13-17 year olds, 42% to 48% reported experiencing mental health concerns. It is estimated that only half of adolescents with mental health problems utilize mental health services (Costello et al., 2014). An initial study found that caregivers of disadvantaged youth appeared to function as the “gatekeepers” to mental health services (Tsang et al., 2020). Also, the results suggested that positive attitude towards professional psychological help, but not stigma, predicted service enrollment. The current …

Reflection: Reducing Long-Term Mortality In Suicidal Adolescents, Nina R. Bihani

Clinical Research in Practice: The Journal of Team Hippocrates

A transformative method to reducing mortality in suicidal adolescents involves a novel approach of educating and empowering their loved ones.

The Effects Of Exercise On Mental Health: A Research Review, Kaylani Benson

Honors College Theses

This research review looks at the effects exercise and physical activity have on mental health. The results of this review are based upon the results of the formal studies that have been included. These studies are Benefits of Exercise on Physical and Mental Health in Rheumatoid Arthritis Patients, Exercise Effects on Mental Health of Preschool Children, The Effect of Morning Exercise on Mental Health of Female Police Employees, Exercise and Mental Health of People Living with HIV: A Systemic Review, Exercise Improves Physical Function and Mental Health of Brain Cancer Survivors: Two Exploratory Case Studies, Effect of Yogic and Physical …

Preparing To Parent: Mindfulness In Expectant Parents Exposed To Adversity, Laurel Marie Hicks

Wayne State University Dissertations

Expectant parents who have been exposed to psychosocial risk encounter deleterious psychological (Ashley et al., 2016), and physiological (V. H. Pereira, Campos, & Sousa, 2017) effects. This not only affects the parent-to-be, but also may affect the developing fetus (E. P. Davis et al., 2011) and is linked to poorer infant development (Lefmann & Combs-Orme, 2014). However, not all risk-exposed individuals experience this, many are resilient and still thrive in the face of adversity. Understanding potential risk and resiliency factors in expectant parents is advantageous, so tailored interventions can be devised to improve outcomes. One potential resiliency factor, mindfulness, is …

This Is Us Saying Who We Are: Speaking The Rhetoric Of Mental Disability, Renuka Uthappa

Wayne State University Dissertations

People with mental disabilities, or what are sometimes referred to as “mental illnesses,” face stigma when they interact with the public. To fight this stigma, the members of a small, grassroots, advocacy organization known as the Speakers Bureau travel to high school and college classrooms narrating their experiences with mental disability. They do so to replace culturally circulating stereotypes regarding such disability with more accurate and positive images. This dissertation is an auto-ethnographic exploration of the rhetoric of the Speakers Bureau. Through rhetorical analysis of members’ classroom speeches, of interviews with each speaker, and of the speaker’s self- assessment of …

Recovery Experiences Amongst Arab American Clubhouse Members: Examining The Effects Of Acculturation, Perceived Family Support, Stigma And Gender On Mental Health Recovery., Layla Habhab

Wayne State University Dissertations

ABSTRACT

RECOVERY EXPERIENCES AMONGST ARAB AMERICAN CLUBHOUSE MEMBERS: EXAMINING THE EFFECTS OF ACCULTURATION, PERCEIVED FAMILY SUPPORT, STIGMA AND GENDER ON MENTAL HEALTH RECOVERY

by

LAYLA HABHAB

August 2016

Advisor: Dr. Francesca Pernice –Duca

Major: Educational Psychology

Degree: Doctor of Philosophy

Recovery from serious mental illness has been conceptualized throughout much of the recent literature as being a multidimensional continuum that is influenced by multiple factors. This notion of recovery has mostly been defined by the personal narratives of survivors, ex –patients and mental health consumers with serious mental illness, who have identified specific factors that have either enhanced or hindered …

Diabetes Interaction Study: Communicating Understanding And Social Support, Dana K. May

Wayne State University Dissertations

The current study evaluated a brief individualized feedback intervention developed to improve communication style of parents with an adolescent with type 1 diabetes. Seventy-nine parent-adolescent dyads (13-18 years) were randomized to receive a single session of brief feedback to target parental person-centered communication skills (n = 39) or to receive an educational comparison group (n = 40). Families were asked to discuss a diabetes related problem. A clinician concurrently rated the parent’s communication skills to identify communication strengths and weaknesses. Parents in the feedback group received feedback on their use of person-centered communication during the conversation using motivational interviewing techniques. …

Evidence Of Distinctive Structural Alterations That Differentiate Adhd Boys With And Without A Comorbid Reading Disability, Dhruman Dilip Goradia

Wayne State University Dissertations

Attention deficit hyperactivity disorder (ADHD) and reading disability (RD) are neurodevelopmental disorders that often co-occur. Children with ADHD and co-occurring RD (ADHD/+RD) tend to show greater cognitive deficits than children with ADHD alone (ADHD/-RD). However, the extents to which comorbid RD impact structural alteration in children with ADHD have never been investigated. The overall goal of this study was to assess structural alterations in the subcortical, cortical and white matter that may differentiate ADHD/-RD from ADHD/+RD. The general hypothesis was that ADHD/+RD would show extensive alterations in regions implicated in ADHD than ADHD/-RD as well as show additional abnormalities in …

Using A Novel Optogenetic Approach To Directly Assess 5-Ht1a Somatodendritic Autoreceptor Function In Response To Chronic Selective Serotonin Reuptake Inhibitor Treatment, Kelly Marie Mcgregor

Wayne State University Dissertations

Antidepressant drugs are widely used but their mechanism of action remains only partially understood. One leading hypothesis holds that a key effect of chronic treatment with a Selective Serotonin Reuptake Inhibitor (SSRI) is loss of somatodendritic 5-HT1A receptor-mediated autoinhibition in serotonergic neurons of the dorsal raphe nucleus (DRN). However, technical limitations have prevented direct testing of this hypothesis. In the current study we took advantage of optogenetic strategies to assess the effects of the classic SSRI fluoxetine on 5-HT1A receptor-mediated autoinhibition. We conducted these experiments in mice expressing the light-sensitive ion channel Channelrhodopsin (ChR) in 5-HT neurons to facilitate their …

Coping Similarity And Psychosocial Risk Factors In Couples With Chronic Pain, Amy M. Williams

Wayne State University Dissertations

Chronic pain is an important public health problem that is associated with a host of negative individual and relationship outcomes. Chronic pain is a chronic stressor that both the individual in pain and their spouse must cope with. The current study examined how pain coping similarity within the couple predicted not only patient adjustment, but also spouse adjustment in a longitudinal study. Participants were 108 heterosexual couples in which one partner had chronic pain. The participants completed measures at 3 time points at 6 month intervals. Both the patient and spouse individually completed questionnaires pertaining to their marriage, mood, pain …

Present Futures: Possibilities For Selfhood At A Community Mental Health Center In Detroit, Michigan, Talia Gordon

Wayne State University Theses

Since the 1990s, recovery-oriented approaches to mental illness have become the dominant paradigm in contemporary U.S. non-clinical institutional settings. Central to the recovery paradigm is a discourse of self-determination that separates psychiatric pathology from personhood and expects those diagnosed to enact and manage themselves as autonomous subjects - as empowered, responsible, independent, and transformable. For many individuals, however, everyday experiences of illness are at odds with expectations for recovery, defined as a "process of change" through which the self is continuously worked upon and improved (SAMHSA 2011). One particularly popular non-clinical recovery modality is the Clubhouse model of psychosocial rehabilitation …

Proximate And Evolutionary Insights Into The Epigenetics Of Posttraumatic Stress Disorder, Levent Sipahi

Wayne State University Dissertations

Posttraumatic stress disorder (PTSD) is an important medical and social condition. Although the vast majority of individuals are exposed to traumatic events within their lifetime, a minority subsequently develop diagnosable PTSD. What underlies differential risk and resiliency in the face of trauma is an ongoing research and clinical question with implications for prevention and treatment. Recent work has revealed a putative role of epigenetic variation and modification - most notably DNA methylation - in the etiology of PTSD. That DNA methylation is stable, yet modifiable in response to lived experiences, makes it a strong candidate to mechanistically explain the ontogeny …

The Relationship Of Rehabilitation Counselors' Knowledge Of The Americans With Disabilities Act 1990, Attitudes Toward Reasonable Accommodation, And Job Development Efficacy, Joy Elizabeth Inniss-Johnson

Wayne State University Dissertations

The purpose of this research was to evaluate the relationship between the rehabilitation counselors' level of knowledge, attitudes towards reasonable accommodations and job development efficacy. The more knowledgeable rehabilitation counselors are about ADA, reasonable accommodations, and their attitude toward job development, the less likely their attitudes will be expected to fluctuate. In addition, there has been very little research in terms of evaluating rehabilitation counselor's level of job placement efficacy. A survey-based design was utilized to create both a quantitative description of knowledge of the ADA, beliefs about reasonable accommodations and job placement efficacy and qualitative information concerning the barriers …

Likelihood Of Asking For Help In Caregivers Of Women With Substance Use Or Co-Occurring Substance Use And Mental Disorders, Suzanne Brown, David E. Biegel, Elizabeth M. Tracy

Social Work Faculty Publications

Family members are important to the well-being of their relatives with substance use disorders or cooccurring substance use and mental disorders. Many caregivers experience high levels of burden, negatively impacting their capacity to provide support to their ill family member. The Andersen health care utilization model (Andersen & Newman, 1973, 2005) was used to identify the impact of predisposing, enabling, and need factors hypothesized to predict caregivers’ likelihood of asking for help and support with their caregiving role. The sample include 82 women recruited from outpatient or inpatient substance abuse treatment centers and 82 family caregivers nominated by these women. …

Social Workers' Knowledge And Attitudes About Treating Children With Attention Deficit Hyperactivity Disorder, Angelah Dawn Gomez

Wayne State University Theses

The current research seeks to understand how social work students and social work professionals increase their knowledge about AD/HD and how they formulate their attitudes about the disorder. The literature provided illustrates the many components of AD/HD risks, etiology, treatments, and professional opinions about the disorder. AD/HD is one of the most studied childhood mental health disorders in the nation. However, there is little research providing insight to social workers' knowledge and attitudes about the disorder. This is especially alarming because social workers are one of the largest professional populations to provide mental health services to children and their families. …

Predictors Of Depressive Symptomatology In Family Caregivers Of Wom-En With Substance Use Disorders Or Co-Occurring Substance Use And Mental Disorders, David E. Biegel, Shari Katz-Saltzman, David Meeks, Suzanne Brown, Elizabeth M. Tracy

Social Work Faculty Publications

This study utilized a stress-process model to examine the impact of having a female family member with substance use or co-occurring substance use and mental disorders on family caregivers' depressive symptomatology. Participants were 82 women receiving substance abuse treatment and the family member providing the most social support for each woman. Greater caregiver depressive symptomatology was predicted by greater care recipient emotional problems, less care recipient social support, and poor caregiver health. Implications of findings for treatment and future research are discussed

A Vignette Study Examining The Accuracy Of Diagnosis: The Role Of Patient And Practitioner Gender And Race Match, Kevin Johnson

Wayne State University Dissertations

ABSTRACT

DIAGNOSING MENTAL ILLNESS

By

KEVIN JOHNSON

2010

Advisor: Dr. Janet R. Hankin

Major: Medical Sociology

Degree: Doctor of Philosophy in Sociology

A convenience snowball sample of 228 mental health practitioners were surveyed and administered two vignettes of persons with mental illness and a 12-question survey that included occupational background and attitudinal questions about diagnosing mental illness. The gender and race of the patients were randomly altered, while the symptoms and characteristics of mental illness remained constant for each vignette. Each practitioner assigned a DSM-IV diagnostic label for axis I and axis II on both vignettes. The surveys were coded …

The Relationships Between Depression And Other Outcomes Of Chronic Illness Caregiving, Pao-Feng Tsai, Mary M. Jirovec

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Many caregivers with chronically ill relatives suffer from depression. However, the relationship of depression to other outcomes of chronic caregiving remains unclear. This study tested a hypothesized model which proposed that hours of care, stressful life events, social support, age and gender would predict caregivers' outcomes through perceived caregiver stress. Depression was expected to mediate the relationship between perceived stress and outcomes of chronic caregiving (physical function, self-esteem, and marital satisfaction).

Methods

The sample for this secondary data analysis consisted of 236 and 271 subjects from the Americans' Changing Lives, Wave 1, 1986, and Wave 2, 1989, data …