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Psychiatric and Mental Health Commons™
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Full-Text Articles in Psychiatric and Mental Health
Experimental Pharmacological Research Regarding The Antidepressant Effect Of Associating Doxepin And Selegiline In Normal Mice, Cornel Chiriță, Emil Ștefănescu, Cristina E. Zbârcea, Horațiu Mireșan, Simona Negreș, Diana C. Nuță, Carmen Limban, Rucsandra E. Dănciulescu Miulescu, Cristina D. Marineci
Experimental Pharmacological Research Regarding The Antidepressant Effect Of Associating Doxepin And Selegiline In Normal Mice, Cornel Chiriță, Emil Ștefănescu, Cristina E. Zbârcea, Horațiu Mireșan, Simona Negreș, Diana C. Nuță, Carmen Limban, Rucsandra E. Dănciulescu Miulescu, Cristina D. Marineci
Journal of Mind and Medical Sciences
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a synergism of action between a classical tricyclic antidepressant that inhibits noradrenalin and serotonin reuptake (doxepin), and a modern antidepressant that inhibits type-B monoamine oxidase (selegiline). We measured the antidepressant effect using the forced swimming test and the tail suspension test. We determined motor activity using the Activity Cage test. Our results have shown that the antidepressant effect intensifies significantly in the …
Comparing Psychiatric Care Experiences Shared Online With Validated Questionnaires; Do They Include The Same Content?, Rebecca Baines, John Donovan, Samantha Regan De Bere, Julian Archer, Ray Jones
Comparing Psychiatric Care Experiences Shared Online With Validated Questionnaires; Do They Include The Same Content?, Rebecca Baines, John Donovan, Samantha Regan De Bere, Julian Archer, Ray Jones
Patient Experience Journal
Patient feedback is considered integral to patient safety and quality of care. However, limited research has compared the content of validated questionnaires with subjective patient experiences shared online. The aim of this study was to therefore identify and compare the content of psychiatric care experiences shared online with validated questionnaires. All research was conducted in co-production with a volunteer mental-health-patient-research-partner. We analysed all reviews published on the United Kingdom’s leading health and social care feedback platform Care Opinion, between 2005-2017 that discussed adult psychiatric care and compared findings with two validated questionnaires (ACP360 and General Medical Council patient feedback questionnaire). …