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Mental and Social Health Commons

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Full-Text Articles in Mental and Social Health

Assessing A Two-Hit Model Of Schizophrenia: Prenatal Choline Deficiency And Induced Hypofunction Of Nmda Receptors In Male And Female Long Evans Rats, Samuel Gray, Samuel W. Gray Jan 2020

Assessing A Two-Hit Model Of Schizophrenia: Prenatal Choline Deficiency And Induced Hypofunction Of Nmda Receptors In Male And Female Long Evans Rats, Samuel Gray, Samuel W. Gray

Honors Theses

Choline is an essential dietary nutrient essential to the development and function of the central nervous system. Prenatal choline deficiency alters hippocampal development as well as acetylcholine metabolism, leading to cognitive impairments and attentional and sensory processing deficits into adulthood. MK-801 is an NMDA receptor antagonist frequently used in rodent models of neuropsychiatric conditions, particularly schizophrenia. Acutely and sub- chronically, it causes hyperlocomotion and social withdrawal. One primary goal of the present study were to investigate prenatal choline deficiency induces a biological vulnerability to the motor deficits, anhedonia, and social impairment precipitated by low-dose sub-chronic MK-801 administration in adulthood. Another …


Health Care Agency: Statewide Awareness Of Patient-Centered Care In Maine’S Mental Health Care Facilities, Holly Hogan A Jan 2016

Health Care Agency: Statewide Awareness Of Patient-Centered Care In Maine’S Mental Health Care Facilities, Holly Hogan A

Honors Theses

This research project focuses on patient-centered care (PCC) in the context of inpatient acute psychiatric units. Hospitals have been claiming their renewed outlooks on health-care via PCC. It has become an increasingly popular term to use on hospital websites and in presidential statements. The technologies and practices surrounding psychiatric care have evolved in such a way that patients are more welcomed to have an input in their care. This project discusses the discourse around PCC at Mental Health Care Facilities in Maine. There is no consensus on the definition; the meanings ascribed to it are derived from the individual institutions. …


The Growing Crisis In Maine: Neonatal Abstinence Syndrome, Olivia Avidan Jan 2015

The Growing Crisis In Maine: Neonatal Abstinence Syndrome, Olivia Avidan

Honors Theses

Neonatal Abstinence Syndrome (NAS) is a Maine epidemic. In addition to having medical repercussions, NAS is intrinsically linked to social, political and economic factors. NAS is a conglomeration of symptoms, short-term and long-term, that affect a child that has been exposed to opioids in utero. These factors that impact NAS are interdependent. The past decade is characterized by a dramatic rise in NAS cases in Maine. This paper explores the social, political and economic landscape surrounding NAS in an effort to describe fully the syndrome’s effect on both individuals and the community as a whole.