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Full-Text Articles in Mental and Social Health

Understanding The Information Needs Of Clients And Caregivers Regarding Early Psychosis: A Conventional Content Analysis, Tanvin K. Juneja Aug 2023

Understanding The Information Needs Of Clients And Caregivers Regarding Early Psychosis: A Conventional Content Analysis, Tanvin K. Juneja

Electronic Thesis and Dissertation Repository

A first episode of psychosis is defined by the first presentation of psychotic symptoms that have gone untreated, characterized by a loss of contact with reality and significant declines in functioning. Low psychosis literacy among clients and caregivers can result in a delay in receiving treatment. This study sought to understand the information needs of clients and caregivers regarding early psychosis. Using a conventional content analysis, we conducted a secondary analysis of 64 transcripts from clients, caregivers, family physicians, and early psychosis intervention clinicians. Clients and caregivers often described having difficulties recognizing symptoms of early psychosis until they became overt …


Data-Driven Neuroanatomical Subtypes In Various Stages Of Schizophrenia: Linking Cortical Thickness, Glutamate, And Language Functioning, Liangbing Liang Dec 2022

Data-Driven Neuroanatomical Subtypes In Various Stages Of Schizophrenia: Linking Cortical Thickness, Glutamate, And Language Functioning, Liangbing Liang

Electronic Thesis and Dissertation Repository

The considerable variation in the spatial distribution of cortical thickness changes has been used to parse heterogeneity in schizophrenia. We aimed to recover a ‘cortical impoverishment’ subgroup with widespread cortical thinning. We applied hierarchical cluster analysis to cortical thickness data of three datasets in different stages of psychosis and studied the cognitive, functional, neurochemical, language and symptom profiles of the observed subgroups. Our consensus-based clustering procedure consistently produced a subgroup characterized by significantly lower cortical thickness. This ‘cortical impoverishment’ subgroup was associated with a higher symptom burden in a clinically stable sample and higher glutamate levels with language impairments in …


Sex Differences In The Clinical Presentation Of Early Psychosis In A Primary Care Setting, Brooke Carter Jun 2022

Sex Differences In The Clinical Presentation Of Early Psychosis In A Primary Care Setting, Brooke Carter

Electronic Thesis and Dissertation Repository

Psychotic disorders can be variable in clinical presentation, and there may be differences by sex. The objective of this thesis was to explore sex differences in the clinical presentation of early psychosis in the context of primary care. Our systematic review and meta-analysis found that men experienced more negative symptoms and had a higher prevalence of substance use issues, whereas women experienced more depressive symptoms and had higher functioning. Our electronic medical record analysis from primary care found that positive symptoms and substance use were less prevalent in the medical records of women. We also found that visits by women …


Long-Term Patterns Of Acute Mental Health Service Use After A First Episode Of Psychosis: Examining Ongoing Psychiatric Care Beyond The Critical Period, Eugene Law Mar 2021

Long-Term Patterns Of Acute Mental Health Service Use After A First Episode Of Psychosis: Examining Ongoing Psychiatric Care Beyond The Critical Period, Eugene Law

Electronic Thesis and Dissertation Repository

The long-term patterns of acute mental health service use after treatment in an early psychosis intervention (EPI) program are not well known. The objective of this thesis was to investigate the long-term patterns of acute mental health service use. We used health administrative data to examine the patterns and risk factors associated with acute mental health service use over the of 5- to 10-year period post-EPI admission. Between years 5 to 10 post-EPI admission, approximately one quarter of people contacted acute mental health services. Factors associated with acute mental health service use during this period included younger age at admission, …