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Vertebral Endplate Structural Defects: Measurement, Prevalence And Associated Factors, Aliyu Lawan
Vertebral Endplate Structural Defects: Measurement, Prevalence And Associated Factors, Aliyu Lawan
Electronic Thesis and Dissertation Repository
Objective: To synthesize current knowledge on the association of endplate structural defects (EPSD) with back pain (BP), improve EPSD measurement, and investigate EPSD prevalence, distribution, and association with age and body mass index (BMI).
Methods: In study 1, a systematic review was conducted on five databases for studies reporting on the association between EPSD and BP. Studies 2 and 3 used CTs and mCTs of 19 embalmed cadavers to examine the diagnostic accuracy of common EPSD assessment methods, and to develop and validate a novel method. Study 4 used the novel method on 200 adult males’ MRI to estimate EPSD …