Health and Medical Administration Commons^™

Ferric Gluconate Yields Cost-Savings In Hemodialysis Patients With High Ferritin And Low Tsat: Results From The Drive Studies, Laura T. Pizzi, Thomas J. Bunz, David S. Goldfarb, Daniel W. Coyne, Ajay K. Singh

College of Population Health Lectures, Presentations, Workshops

Purpose: One third of hemodialysis patients have high serum ferritin levels and low transferrin saturation (TSAT). The purpose of this analysis was to determine the cost effectiveness of administering 1g of sodium ferric gluconate complex (SFGC: also referred to as ferric gluconate) to patients with serum ferritin >500ng/mL and TSAT ≤25% based on the Dialysis Patients Response to IV Iron with Elevated Ferritin (DRIVE) study and its 6-week observational extension (DRIVE-II). In these studies, IV iron administration resulted in reduced epoetin requirements.

Methods: Decision analysis was performed using a time horizon of 12 weeks, consistent with the combined duration of …