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Full-Text Articles in Diseases

Associations Among Psychosocial Factors, Health-Related Quality Of Life, And Adherence In Pediatric Inflammatory Bowel Disease, Cecelia I. Nelson Jan 2024

Associations Among Psychosocial Factors, Health-Related Quality Of Life, And Adherence In Pediatric Inflammatory Bowel Disease, Cecelia I. Nelson

Graduate Theses, Dissertations, and Problem Reports

Inflammatory Bowel Disease (IBD) is a prevalent disorder among youth in the United States. IBD is one of the leading causes of chronic pain in adolescence and symptoms can lead to reduced quality of life, social embarrassment, and lower self-esteem. Adherence to medical regimens for IBD is incredibly important to prevent morbidity, mortality, and impaired health-related quality of life (HRQOL). However, adolescents struggle generally with adherence and the regimen for IBD can be complicated and include aversive side effects. Psychological factors, such as depressive symptoms, are key factors associated with non-adherence. Nevertheless, gut-specific anxiety (GSA) is a psychological factor that …


A Role For Endothelial Tissue-Nonspecific Alkaline Phosphatase In Blood-Tissue Barrier Health And Disease, Allison L. Brichacek Jan 2021

A Role For Endothelial Tissue-Nonspecific Alkaline Phosphatase In Blood-Tissue Barrier Health And Disease, Allison L. Brichacek

Graduate Theses, Dissertations, and Problem Reports

Sepsis is a disorder that targets the microcirculation with significant effects at blood-tissue barriers such as the blood-brain barrier (BBB) and gut-vascular barrier (GVB). Intestinal barrier dysfunction is thought to be one of the most important contributors to multi-organ dysfunction in sepsis. As a common site of infection, the impaired gut allows the dissemination of bacteria, which exacerbates the disease pathophysiology, and can lead to long-term morbidity and mortality. The mechanisms that influence altered barrier permeability in the GVB in sepsis and other inflammatory disorders are not well understood. Tissue-nonspecific alkaline phosphatase (TNAP) enzyme activity, which has been shown to …


Esophageal Crohn's Disease Unresponsive To Glucocorticoids, Tanureet Kochar, Matthew Krafft, Swapna Gayam Jan 2019

Esophageal Crohn's Disease Unresponsive To Glucocorticoids, Tanureet Kochar, Matthew Krafft, Swapna Gayam

Faculty & Staff Scholarship

No abstract provided.


Analysis Of The Patient Information Quality And Readability On Esophagogastroduodenoscopy (Egd) On The Internet, P. Priyanka, Yousaf B. Hadi, G.J. Reynolds Jan 2018

Analysis Of The Patient Information Quality And Readability On Esophagogastroduodenoscopy (Egd) On The Internet, P. Priyanka, Yousaf B. Hadi, G.J. Reynolds

Faculty & Staff Scholarship

Objective. Patients are increasingly using the Internet to inform themselves of health-related topics and procedures, including EGD. We analyzed the quality of information and readability of websites after a search on 3 different search engines. Methods. We used an assessment tool for website quality analysis that we developed in addition to using validated instruments for website quality, Global Quality Score (GQS) and Health on Net (HON) certification. The readability was assessed using Flesch-Kincaid Reading Ease (FRE) and Flesch-Kincaid Grade level (FKG). 30 results of each search terms ‘EGD’ and ‘Upper Endoscopy’ from Google and 15 each from Bing and Yahoo …


Endoscopic And Pathologic Resolution Of Chronic Nonsteroidal Anti-Inflammatory Drug-Induced Diaphragm-Like Colonic Strictures And Ulceration, Behdod Poushanchi, Hiren Vallabh, Justin Kupec Jan 2018

Endoscopic And Pathologic Resolution Of Chronic Nonsteroidal Anti-Inflammatory Drug-Induced Diaphragm-Like Colonic Strictures And Ulceration, Behdod Poushanchi, Hiren Vallabh, Justin Kupec

Faculty & Staff Scholarship

The chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) has steadily increased and, as a result, adverse effects have become more common. Isolated case reports have documented diaphragm-like colonic strictures and ulceration as the result of NSAID use. We report a unique case of this rare side effect with documented endoscopic and histologic healing of multiple proximal diaphragm-like colonic strictures and ulceration months after simple discontinuation of NSAID therapy.


Hepatology Mentorship: A Bold Idea, Christina C. Lindenmeyer, Elizabeth May Jan 2018

Hepatology Mentorship: A Bold Idea, Christina C. Lindenmeyer, Elizabeth May

Faculty & Staff Scholarship

No abstract provided.