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Novel Protective Salivary Peptides And The Chitosan Nanoparticles Delivery System, Flavia Zaidan Cardoso Salina Jul 2015

Novel Protective Salivary Peptides And The Chitosan Nanoparticles Delivery System, Flavia Zaidan Cardoso Salina

Electronic Thesis and Dissertation Repository

As a result of its protein composition, saliva performs many essential functions that contribute to oral homeostasis. However, salivary proteins suffer quick degradation in the oral cavity, which decreases the protective potential of that fluid (Chapter 2). Using scanning electron microscopy (SEM), we evaluated the effect of our novel salivary peptides DR9, DR9-DR9, DR9-RR14 and RR14 on the crystallization of calcium oxalate (CaOx). All peptides containing DR9 showed significant inhibitory effect on the crystallization of CaOx, whereas RR14 showed no effect (Chapter 3). Next, we tested the adsorption behavior of our chitosan nanoparticles (CHNP) delivery system to hydroxyapatite (HA) surface …


The Effective Dose Of Different Scanning Protocols Using The Sirona Galileos® Comfort Cbct Scanner, David R. Chambers Dec 2013

The Effective Dose Of Different Scanning Protocols Using The Sirona Galileos® Comfort Cbct Scanner, David R. Chambers

Electronic Thesis and Dissertation Repository

Introduction: Cone Beam CT imaging is prevalent in dentistry yet much is unknown with regard to how radiation dose to the patient varies between different CBCT scanners and imaging protocols. Scanner and protocol specific effective dose calculations will aid in optimizing individualized protocols for clinical applications.

Purpose: To determine the effective dose for a range of imaging protocols using the Sirona GALILEOS Comfort CBCT scanner.

Materials and Methods: Calibrated InLight nanoDot OSL dosimeters (Landauer, Glenwood, Ill) were placed at 26 select sites in the head and neck of a modified, human tissue-equivalent RANDO phantom. Effective dose was calculated using …