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Dentistry Commons

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School of Dentistry Faculty Research and Publications

2021

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Full-Text Articles in Dentistry

Oral Manifestations Of Syphilis: A Review Of The Clinical And Histopathologic Characteristics Of A Reemerging Entity With Report Of 19 New Cases, Molly Housley Smith, Richard J. Vargo, Elizabeth Ann Bilodeau, K. Mark Anderson, Anna Trzcinska, Carleigh R. Canterbury, John E. Fantasia, Yeshwant B. Rawal Sep 2021

Oral Manifestations Of Syphilis: A Review Of The Clinical And Histopathologic Characteristics Of A Reemerging Entity With Report Of 19 New Cases, Molly Housley Smith, Richard J. Vargo, Elizabeth Ann Bilodeau, K. Mark Anderson, Anna Trzcinska, Carleigh R. Canterbury, John E. Fantasia, Yeshwant B. Rawal

School of Dentistry Faculty Research and Publications

Background

Syphilis is a sexually-transmitted infectious disease caused by Treponema pallidum. Cases of primary and secondary syphilis are on the rise in the United States, with a 14.4% increase in new cases noted from 2017 to 2018 and an escalation of 71% between the years 2014 and 2018. Fulfilling its nickname of “the great imitator,” oral manifestations of syphilis may mimic a variety of infectious, neoplastic, or immune-mediated processes, both clinically and histopathologically. This large spectrum of appearances can create a diagnostic challenge to the clinician and/or pathologist, leading to delay in diagnosis or misdiagnosis.

Methods

A database of …